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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T70484 AD-35

AD-35 is a neuroprotectant for treating Alzheimer’s diseases by significantly inhibiting the production and release of proinflammatory cytokines TNF-α and IL-1β.
T78688 HPK1-IN-35

HPK1-IN-35，作为一种选择性的HPK1抑制剂，表现出了3.5 nM的强效IC50。该化合物能够抑制p-SLP76的表达并增强IL-2的分泌。
T37590 ML 3403

p38 MAPK inhibitor (IC50 = 0.38 μM). Inhibits the release of IL-1β and TNF-α in a peripheral blood mononuclear cell (PBMC) assay (IC50 values are 0.039 and 0.16 μM respectively). Laufer et al (2003) Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes. J.Med.Chem. 46 3230 PMID:12852754 |Kammerer et al (2007) Pharmacokinetics of ML3403 ({4-[5-(4-fluorophenyl)-2-methylsulfanyl-3H-imidazol-4-yl]-pyridin-2-yl}-(1-phenylethyl)-...
T38106 JC-171

JC-171 is a selective NLRP3 inflammasome inhibitor, with an IC50 of 8.45 μM for inhibiting LPS/ATP-induced interleukin-1β (IL-1β) release from J774A.1 macrophages[1]. JC-171 (0-100 μM) blocks NLRP3 inflammasome activation and IL-1β production in primary macrophages dose dependently[1]. ...

化合物

AD-35
Cat.No: T70484
Synonym:
Target:
HPK1-IN-35
Cat.No: T78688
Synonym:
Target:
ML 3403
Cat.No: T37590
Synonym:
Target:
JC-171
Cat.No: T38106
Synonym:
Target:
Species：
Human (13)
Mouse (3)
Rat (2)
Marmoset (1)
Rabbit (1)
Rhesus (1)
Expression System：
HEK293 (20)
Human Cells (1)
Tag：
His (7)
hFc (7)
Tag Free (3)
Fc-Flag,Fc-His (1)
Flag,His (1)
None (1)
mFc (1)
Cat. No. Product Name Species Expression System
TMPY-04793 IL-35 Protein, Human, Recombinant (Flag & His)

NKSF1,P35,白介素,Interleukin-35,CLMF,白细胞介素,NF...

 Human HEK293
IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. IL12A, together with IL27B, form a disulfide-linked heterodimer: IL12A&IL27B. IL12A&IL27B is required for the T-cell-independent induction of IFN-gamma and is important for the differentiation of both Th1 and T...
TMPY-03879 IL-35 Protein, Human, Recombinant

白介素,P35,NFSK,NKSF1,IL-12A,Interleukin-...

 Human HEK293
IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. IL12A, together with IL27B, form a disulfide-linked heterodimer: IL12A&IL27B. IL12A&IL27B is required for the T-cell-independent induction of IFN-gamma and is important for the differentiation of both Th1 and T...
TMPY-06105 IL-35 Protein, Human, Recombinant (Fc-Flag & Fc-His)

P35,interleukin 12A,IL-35,NFSK,

Human HEK293
IL12A is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. IL12A, together with IL27B, form a disulfide-linked heterodimer: IL12A&IL27B. IL12A&IL27B is required for the T-cell-independent induction of IFN-gamma and is important for the differentiation of both Th1 and T...
TMPY-04863 IL-12 Protein, Human, Recombinant

IMD29,CLMF,IL12,NFSK,白细胞介素,IL-12A,interleu...

 Human HEK293
IL-12 Protein, Human, Recombinant is expressed in HEK293. The predicted molecular weight is 57.2 kDa. Accession number: P29459-1&NP_002178.2
TMPY-00838 IL-12A Protein, Human, Recombinant (hFc)

IL-12A,NKSF1,NFSK,CLMF,P35,interleukin 12A

 Human HEK293
Interleukin-12 subunit alpha (IL12A/IL-12p35) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit, cytotoxic lymphocyte maturation factor 1, p35, NK cell stimulatory factor chain 1, and interleukin-12 alpha chain. IL12A/IL-12p35 is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member o...
TMPY-01409 IL-12A Protein, Human, Recombinant (His)

NKSF1,P35,NFSK,IL-12A,interleukin 12A,CLMF

 Human HEK293
Interleukin-12 subunit alpha (IL12A/IL-12p35) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit, cytotoxic lymphocyte maturation factor 1, p35, NK cell stimulatory factor chain 1, and interleukin-12 alpha chain. IL12A/IL-12p35 is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member o...
TMPY-02109 IL-12 Protein, Human, Recombinant (His)

IL12,NKSF1,IMD28,CLMF2,白细胞介素,NKSF2,NKSF,CLMF,IMD29,...

 Human HEK293
IL-12 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 60.13 kDa. Accession number: P29459-1&NP_002178.2
TMPY-05458 IL-12 Protein, Human, Recombinant (His), Biotinylated

NKSF,IL-12A,白细胞介素,白介素,interleukin 12A,IMD29,NFSK,NK...

 Human HEK293
IL-12 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 with His tag. The predicted molecular weight is 60.13 kDa. Accession number: P29459.2&NP_002178.2
TMPY-04874 IL-23 P19/IL23A Protein, Human, Recombinant (hFc)

IL-23A,IL-23,interleukin 23, alpha subunit...

 Human HEK293
IL-23, which is mainly secreted by antigen-presenting cells, is a member of the IL-12 family, which includes IL-12, IL-27, and IL-35. IL-23 is a heterodimeric cytokine, comprised of a unique p19 subunit and p4 subunit, the latter of which is shared with IL-12. The receptor for IL-23 consists of IL-23R and IL-12Rβ1, the latter of which is also characteristic of IL-12. IL-23 is essential for Th17 differentiation, expansion, and survival by binding to its receptor, thereby activating the signaling ...
TMPY-03516 IL-12B Protein, Mouse, Recombinant

Il-12p40,interleukin 12B,Il-12b,Il

Mouse HEK293
Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts on T and natural killer cells and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B/IL-12B is expressed by activated ...
TMPY-01045 IL-12B Protein, Human, Recombinant (His)

IL-12B,IMD28,CLMF,CLMF2,NKSF2,IL12 p40,IMD...

 Human HEK293
Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts on T and natural killer cells and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B/IL-12B is expressed by activated ...
TMPY-03198 IL-12B Protein, Mouse, Recombinant (His)

Il-12p40,p40,interleukin 12B,Il12p40,I...

 Mouse HEK293
Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts on T and natural killer cells and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B/IL-12B is expressed by activated ...
TMPY-04987 IL-23 P19/IL23A Protein, Human, Recombinant (mFc)

IL-23,interleukin 23, alpha subunit p19,SGRF,IL...

 Human HEK293
IL-23, which is mainly secreted by antigen-presenting cells, is a member of the IL-12 family, which includes IL-12, IL-27, and IL-35. IL-23 is a heterodimeric cytokine, comprised of a unique p19 subunit and p4 subunit, the latter of which is shared with IL-12. The receptor for IL-23 consists of IL-23R and IL-12Rβ1, the latter of which is also characteristic of IL-12. IL-23 is essential for Th17 differentiation, expansion, and survival by binding to its receptor, thereby activating the signaling ...
TMPY-04105 IL-12A Protein, Rhesus, Recombinant (hFc)

interleukin 12A

 Rhesus HEK293
Interleukin-12 subunit alpha (IL12A/IL-12p35) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit, cytotoxic lymphocyte maturation factor 1, p35, NK cell stimulatory factor chain 1, and interleukin-12 alpha chain. IL12A/IL-12p35 is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member o...
TMPJ-00216 IL-12B Protein, Human, Recombinant

Interleukin-12 subunit beta,IL-12B,CLMF p40,NKSF2,I...

 Human Human Cells
Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells develop...
TMPY-00259 IL-12B Protein, Rabbit, Recombinant (His)

interleukin 12B

 Rabbit HEK293
Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts on T and natural killer cells and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B/IL-12B is expressed by activated ...
TMPY-03309 IL-12B Protein, Rat, Recombinant (His)

interleukin 12B

 Rat HEK293
Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts on T and natural killer cells and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B/IL-12B is expressed by activated ...
TMPY-00839 IL-12B Protein, Human, Recombinant (hFc)

IMD29,IL-12B,interleukin 12B,CLMF2,IL12 p4...

 Human HEK293
Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts on T and natural killer cells and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B/IL-12B is expressed by activated ...
TMPY-00458 IL-12B Protein, Rat, Recombinant (hFc)

interleukin 12B

 Rat HEK293
Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts on T and natural killer cells and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B/IL-12B is expressed by activated ...
TMPY-02366 IL-12B Protein, Mouse, Recombinant (hFc)

Il-12p40,interleukin 12B,Il-12b,p40,Il...

 Mouse HEK293
Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts on T and natural killer cells and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B/IL-12B is expressed by activated ...
TMPY-03671 IL-12B Protein, Marmoset, Recombinant (hFc)

interleukin 12B

 Marmoset HEK293
Subunit beta of interleukin 12 (also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40) (IL12B) is a subunit of human interleukin 12. IL12B/IL-12B is a cytokine that acts on T and natural killer cells and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor-like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. IL12B/IL-12B is expressed by activated ...

重组蛋白

IL-35 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPY-04793
Species: Human
Expression System: HEK293
IL-35 Protein, Human, Recombinant
Cat.No: TMPY-03879
Species: Human
Expression System: HEK293
IL-35 Protein, Human, Recombinant (Fc-Flag & Fc-His)
Cat.No: TMPY-06105
Species: Human
Expression System: HEK293
IL-12 Protein, Human, Recombinant
Cat.No: TMPY-04863
Species: Human
Expression System: HEK293
IL-12A Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00838
Species: Human
Expression System: HEK293
IL-12A Protein, Human, Recombinant (His)
Cat.No: TMPY-01409
Species: Human
Expression System: HEK293
IL-12 Protein, Human, Recombinant (His)
Cat.No: TMPY-02109
Species: Human
Expression System: HEK293
IL-12 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05458
Species: Human
Expression System: HEK293
IL-23 P19/IL23A Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04874
Species: Human
Expression System: HEK293
IL-12B Protein, Mouse, Recombinant
Cat.No: TMPY-03516
Species: Mouse
Expression System: HEK293
IL-12B Protein, Human, Recombinant (His)
Cat.No: TMPY-01045
Species: Human
Expression System: HEK293
IL-12B Protein, Mouse, Recombinant (His)
Cat.No: TMPY-03198
Species: Mouse
Expression System: HEK293
IL-23 P19/IL23A Protein, Human, Recombinant (mFc)
Cat.No: TMPY-04987
Species: Human
Expression System: HEK293
IL-12A Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-04105
Species: Rhesus
Expression System: HEK293
IL-12B Protein, Human, Recombinant
Cat.No: TMPJ-00216
Species: Human
Expression System: Human Cells
IL-12B Protein, Rabbit, Recombinant (His)
Cat.No: TMPY-00259
Species: Rabbit
Expression System: HEK293
IL-12B Protein, Rat, Recombinant (His)
Cat.No: TMPY-03309
Species: Rat
Expression System: HEK293
IL-12B Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00839
Species: Human
Expression System: HEK293
IL-12B Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-00458
Species: Rat
Expression System: HEK293
IL-12B Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02366
Species: Mouse
Expression System: HEK293
IL-12B Protein, Marmoset, Recombinant (hFc)
Cat.No: TMPY-03671
Species: Marmoset
Expression System: HEK293
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