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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T5523 |
Imidazole ketone erastin
IKE |
Ferroptosis | Apoptosis |
Imidazole ketone erastin (IKE) 是一种铁死亡诱导剂,对 system Xc-胱氨酸/谷氨酸转运蛋白具有抑制作用。Imidazole ketone erastin 具有抗肿瘤活性,可以诱导谷胱甘肽耗竭和脂质过氧化。 | |||
T10389L |
Aspartyl-alanyl-diketopiperazine acetate
DA-DKP,Aspartyl-alanyl-diketopiperazine acetate(110954-19-3 Free base) |
Others | Others |
Aspartyl-alanyl-diketopiperazine acetate (DA-DKP) 可以通过与 T 淋巴细胞无反应有关的分子途径调节炎症免疫反应。 | |||
T25956 |
Piketoprofen
Calmatel |
Others | Others |
Piketoprofen (Calmatel) 是一种局部非甾体抗炎药。 | |||
TP1057L |
Phe-Met-Arg-Phe Like Peptide acetate
Pqdpflrfamide acetate,Phe-Met-Arg-Phe Like Peptide acetate(98495-35-3 free base) |
Others | Others |
Phe-Met-Arg-Phe Like Peptide acetate (Pqdpflrfamide acetate)(98495-35-3 free base) 是一种来自蜗牛 Helix aspersa 的内脏和躯体肌肉的 FMRF 样肽。 FMRF (Phe-Met-Arg-Phe) 是一种由 4 个氨基酸残基组成的神经肽肽。 | |||
T10389 |
Aspartyl-alanyl-diketopiperazine
DA-DKP |
Interleukin | Immunology/Inflammation |
Aspartyl-alanyl-diketopiperazine (DA-DKP) 是一种由人血白蛋白的 N 端裂解和环化产生的免疫调节分子,通过与 T 淋巴细胞无反应相关的分子途径调节炎症免疫反应。 | |||
TP2501 |
Difelikefalin acetate
Difelikefalin acetate(1024828-77-0 free base),CR 845 acetate,Difelikefalin醋酸盐,FE 202845 acetate |
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
Difelikefalin acetate (CR 845 acetate) 是一种外周受限的 kappa 阿片受体激动剂。CR845 表现出低 P450 CYP 抑制和对大脑的低渗透性。 | |||
TP2485 |
difelikefalin acetate(1024828-77-0 Free base)
|
Opioid Receptor | Endocrinology/Hormones; GPCR/G Protein; Neuroscience |
difelikefalin acetate 是酮体和砌块。 | |||
T69537 | Difelikefalin HCl | ||
Difelikefalin is a κ-opioid receptor (KOR) agonist. It activates KOR in HEK293 cells expressing the human receptor (EC50 = 0.16 nM in a transactivation assay) and inhibits forskolin-induced cAMP production in R1.G1 mouse thyoma cells (EC50 = 0.048 nM). Difelikefalin is selective for KOR over the μ-opioid receptor (MOR; EC50 = >1 µM in a transactivation assay). It reduces acetic acid-induced writhing, as well as scratching behavior induced by the KOR antagonist GNTI, in mice (ED50s = 0.07 and 0.0... | |||
T34138 |
Prolyldiketopiperazine B
Homoleucyl-D-proline lactam, L-,L-Homoleucyl-D-proline lactam |
||
Prolyldiketopiperazine B is a proline-based diketopiperazine. | |||
T13182 | Toll-like receptor modulator | TLR | Immunology/Inflammation |
Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function. | |||
T73339 |
Anrikefon
HSK21542 |
||
Anrikefon (HSK21542) 为 kappa 阿片受体(kappa opioid receptor)激动剂,具缓解疼痛作用。 | |||
T75116 | COVID-19 Spike Protein mRNA-LNP | ||
COVID-19 Spike Protein mRNA-LNP 是一种RNA传递系统,利用脂质纳米粒(LNP)封装COVID-19 Spike Protein mRNA,提高翻译效率与细胞活性。COVID-19 Spike Protein,位于新冠病毒膜表面,负责与宿主细胞受体结合和膜融合,是病毒进入细胞的关键因素,同时也是疫苗设计与宿主中和抗体生成的核心靶点。 | |||
T82832 |
Bombinin-like peptide 3
BLP-3 |
||
Bombinin-like peptide 3,亚洲蟾蜍Bombina orientalis皮肤分泌物中的一种抗菌肽。 | |||
T82831 |
Bombinin-like peptide 4
BLP-4 |
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Bombinin-like peptide 4为源自亚洲蟾蜍Bombina orientalis皮肤分泌物的抗菌肽。 | |||
TP1148L |
Glucagon-like peptide 1 (1-37), human acetate
|
Glucagon Receptor | GPCR/G Protein |
Glucagon-like peptide 1 (1-37), human acetate 是一种高效的 GLP-1 受体激动剂。 | |||
T17827 |
Diketone-PEG12-DBCO
|
Others | Others |
Diketone-PEG12-DBCO is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T36724 |
6,15-diketo-13,14-dihydro Prostaglandin F1α
6,15-diketo-13,14-dihydro Prostaglandin F1α |
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6,15-diketo-13,14-dihydro PGF1α is a metabolite of PGI2. It was shown to enhance intracellular cAMP and cholesterol catabolism in bovine arterial smooth muscle cells. | |||
T125229 |
Yashabushiketol
|
||
Yashabushiketol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125229,CAS号为 24192-00-5。 | |||
T32790 |
Lisinopril R,S,S-diketopiperazine
Lisinopril specified impurity D |
||
Lisinopril R,S,S-diketopiperazine is a bioactive chemical. | |||
T75102 | COVID-19 Spike Protein mRNA(N1-Me-Pseudo UTP) | ||
COVID-19 Spike Protein mRNA 用于表达新型冠状病毒肺炎刺突蛋白,关键于 RNA 传递、翻译效率与细胞活力的检测。该蛋白定位于病毒膜表面,主导病毒与宿主细胞膜受体的结合及膜融合,促使 COVID-19 病毒入侵细胞。同时,它是宿主中和抗体作用的主要位点与疫苗开发的核心靶标。 | |||
T36654 |
Anti-SARS-CoV-2 Spike mAb (CR3022)
Anti-SARS-CoV-2 Spike mAb (CR3022) |
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Anti-SARS-CoV-2 Spike mAb (CR3022) is a human monoclonal IgG1 antibody derived from CHO cells. It specifically targets the S1 domain of the Spike protein in both SARS-CoV and SARS-CoV-2. | |||
T76330 |
Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide
|
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Human glucagon-like peptide-1-(7-36)-Lys(Biotin) amide 是一种带有生物素标签的Glucagon-like peptide-1-(7-36),后者为一种具备提升胰岛素释放功能,从而表现出抗糖尿病活性的胃肠道肽。 | |||
T80145 |
Galanin-Like Peptide (porcine)
|
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
Galanin-Like Peptide (porcine) 是由60个氨基酸组成的神经肽,原始分离自猪下丘脑。这一肽类对GALR2受体表现出高度亲和力(IC50为0.24 nM),而对GALR1受体则表现出较低的亲和性(IC50为4.3 nM)。 | |||
T82830 |
Bombinin-like peptide 7
BLP-7,Maximin 6 |
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Bombinin-like peptide 7为来源于东方铃蟾的抗菌肽。 | |||
T76539 |
Insulin-like growth factor II
|
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Insulin-like growth factor II (IGF-2)为人血清中主要生长激素,对神经突生长具有许可性和直接作用,同时增强交感与感觉神经元的生存能力。 | |||
T17825 |
Diketone-PEG11-PFP ester
|
Others | Others |
Diketone-PEG11-PFP ester serves as a PEG-based PROTAC linker for PROTAC synthesis[1]. | |||
T76085 |
Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human
|
||
Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human 是一种被 C 端标记的生物素化 GLP-1(7-36) 酰胺。 | |||
T80144 |
Galanin-Like Peptide (human)
|
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
Galanin-Like Peptide (human) 是由60个氨基酸组成的神经肽,在调节摄食、体重和能量代谢方面具有重要功能。 | |||
TP1487 |
Glucagon-Like Peptide (GLP) II, human
|
||
Glucagon-like peptide 2 (GLP-2) is a recently identified intestinal epithelium-specific growth factor that has been shown to reduce the severity of inflammatory disorders of the intestine in rodent models. Currently Glucagon-Like Peptide 2 is used as a po | |||
T82833 |
Bombinin-like peptide 2
BLP-2 |
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Bombinin-like peptide 2, 源自亚洲蟾蜍Bombina orientalis的皮肤分泌物,为一种具有抗菌功能的肽。 | |||
T17828 |
Diketone-PEG4-Biotin
|
Others | Others |
Diketone-PEG4-Biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T37483 | Difelikefalin (trifluoroacetate salt) | ||
Difelikefalin is a κ-opioid receptor (KOR) agonist.1It activates KOR in HEK293 cells expressing the human receptor (EC50= 0.16 nM in a transactivation assay) and inhibits forskolin-induced cAMP production in R1.G1 mouse thyoma cells (EC50= 0.048 nM). Difelikefalin is selective for KOR over the μ-opioid receptor (MOR; EC50= >1 μM in a transactivation assay). It reduces acetic acid-induced writhing, as well as scratching behavior induced by the KOR antagonist GNTI, in mice (ED50s = 0.07 and 0.05 m... | |||
T36656 | Anti-Spike-RBD Single Domain mAb | ||
The Anti-Spike-RBD Single Domain mAb is a monoclonal antibody derived from CHO cells in Alpaca. It is composed of VHH-huFc and exhibits a strong affinity for the SARS-CoV-2 RBD. [1] | |||
T36655 | Anti-Spike-RBD mAb | ||
Anti-Spike-RBD mAb is a CHO cell derived human monoclonal IgG1 antibody. Blocking the interaction of spike protein and ACE2 is a potential therapeutic approach for SARS-CoV-2 treatment[1]. [1]. Chunyan Wang, et al. A Human Monoclonal Antibody Blocking SARS-CoV-2 Infection. Nat Commun. 2020 May 4;11(1):2251. | |||
TP1057 |
Phe-Met-Arg-Phe Like Peptide, Snail Helix aspersa
Phe-Met-Arg-Phe Like Peptide |
||
Phe-Met-Arg-Phe-like peptide, derived from the visceral and somatic muscles of the snail Helix aspersa, is a neuropeptide known as FMRF (Phe-Met-Arg-Phe). This peptide comprises four amino acid residues[1]. | |||
TP1754 |
Bombinin-Like Peptide (BLP-1)
Bombinin-Like Peptide BLP-1 |
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Bombinin-Like Peptide (BLP-1) is an antimicrobial peptide from Bombina species. | |||
T17824 |
Diketone-PEG11-Diketone
|
Others | Others |
Diketone-PEG11-Diketone is a polyethylene glycol (PEG)-based linker utilized for the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. | |||
T69530 | Difelikefalin TFA | ||
Difelikefalin is a κ-opioid receptor (KOR) agonist. It activates KOR in HEK293 cells expressing the human receptor (EC50 = 0.16 nM in a transactivation assay) and inhibits forskolin-induced cAMP production in R1.G1 mouse thyoma cells (EC50 = 0.048 nM). Difelikefalin is selective for KOR over the μ-opioid receptor (MOR; EC50 = >1 µM in a transactivation assay). It reduces acetic acid-induced writhing, as well as scratching behavior induced by the KOR antagonist GNTI, in mice (ED50s = 0.07 and 0.0... | |||
T34207 |
Pyroglutamylglutamine diketopiperazine
Pglu-glu dkm |
||
Pyroglutamylglutamine diketopiperazine is a bioactive chemical. | |||
T17829 | Diketone-PEG4-PFP ester | Others | Others |
Diketone-PEG4-PFP ester is a polyethylene glycol (PEG) derivative employed as a PROTAC linker in the fabrication of proteolysis-targeting chimeras (PROTACs)[1]. | |||
T38419 |
Difelikefalin
CR-845,FE-202845 |
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Difelikefalin (CR-845; FE-202845) is a peripherally restricted, selective agonist of the kappa opioid receptor (KOR). It exhibits anti-inflammatory properties and holds promise for modulating pruritus in conditions associated with chronic kidney disease. | |||
TP1148 |
Glucagon-like peptide 1 (1-37), human
HuGLP-1 |
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Glucagon-like peptide 1 (1-37), human is a highly potent agonist of the GLP-1 receptor.Pancreatic hormone synthesized by post-translational processing of proglucagon. Unlike truncated forms of GLP-1, it has no effect on food intake in rats and does not en | |||
TP1147 |
Glucagon-like peptide 1 (1-37), human TFA
HuGLP-1 TFA |
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Glucagon-like peptide 1 (1-37), human (TFA) is a highly potent agonist of the GLP-1 receptor, it is a kind of pancreatic hormone synthesized by post-translational processing of proglucagon. | |||
T80146 |
Galanin-Like Peptide (rat)
|
Neuropeptide Y Receptor | GPCR/G Protein; Neuroscience |
Galanin-Like Peptide (rat) 是含60个氨基酸的神经肽,主要功能是调节摄食、体重及能量代谢。 | |||
T17826 |
Diketone-PEG12-Biotin
|
Others | Others |
Diketone-PEG12-Biotin is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T125228 |
Dihydroyashabushiketol
|
||
Dihydroyashabushiketol 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125228,CAS号为 24192-01-6。 |
Cat. No. | Product Name | Target | Signaling Pathways |
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TN5830 |
Campsiketalin
Rengyoxide dimethyl ketal |
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Campsiketalin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5830,CAS号为 93675-96-8。 |