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Targets Recommended: VEGFR FGFR FLT PDGFR c-Kit

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抑制剂 & 化合物

2

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Cat. No. Product Name Target Signaling Pathways
T6479 Dovitinib lactate hydrate

Dovitinib (TKI258) Lactate,多韦替尼,Dovitinib Lactate,TKI258

VEGFR; FGFR; FLT; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Dovitinib lactate hydrate (TKI258) 是一种多靶点的酪氨酸激酶抑制剂,抑制 FLT3,c-Kit,FGFR1/3,VEGFR1/2/3和 PDGFRα/β的 IC50值分别为 1,2,8/9,10/13/8,27/210 nM。
T6193 Dovitinib Dilactic Acid

Dovitinib (TKI-258) Dilactic Acid,TKI258 Dilactic acid

VEGFR; FGFR; FLT; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Dovitinib Dilactic Acid (Dovitinib(TKI-258) Dilactic Acid) 是 Dovitinib 的双乳酸,是一种多靶点 RTK 抑制剂,主要用于 III 类 (FLT3/c-Kit),IC50 为 1 nM/2 nM,对 IV 类 (FGFR1/ 3) 和 V 类 (VEGFR1-4) RTK,IC50 为 8-13 nM,对 InsR、EGFR、c-Met、EphA2、Tie2、IGFR1 和 HER2 的效力较低。

化合物

Dovitinib lactate hydrate
Cat.No: T6479
Synonym: Dovitinib (TKI258) Lactate,多韦替尼,Dovitinib Lactate,TKI258
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
Dovitinib Dilactic Acid
Cat.No: T6193
Synonym: Dovitinib (TKI-258) Dilactic Acid,TKI258 Dilactic acid
Target: VEGFR, FGFR, FLT, c-Kit
Cat. No. Product Name Species Expression System
TMPK-00240 Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi)

FcgRI,IGFR1,FCE1A,FCGR1A...

Human HEK293 Cells
The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma  RI (also known as CD64), Fc gamma  RII (CD32), and Fc gamma  RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type. Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 33.5 kDa and...
TMPK-00241 Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi), Biotinylated

FcERI,CD64,FLJ18345,IGFR1,Fc gamm...

Human HEK293 Cells
The Fc gamma Rs have been divided into three classes based on close relationships in their extracellular domains; these groups are designated Fc gamma  RI (also known as CD64), Fc gamma  RII (CD32), and Fc gamma  RIII (CD16). Each group may be encoded by multiple genes and exist in different isoforms depending on species and cell type. Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight i...

重组蛋白

Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00240
Species: Human
Expression System: HEK293 Cells
Fc gamma RI/CD64 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00241
Species: Human
Expression System: HEK293 Cells
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