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10

抑制剂 & 化合物

1

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Cat. No. Product Name Target Signaling Pathways
T8721L I-37 free base( 2359690-13-2(free base))

Raf MAPK
I-37 free base( 2359690-13-2(free base)) 是一种新型苄氨基取代的吡啶并嘧啶酮,可作为 SOS1 抑制剂。
T8721 I-37

Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-6-(1-methylcyclopropyl)-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-

Raf MAPK
I-37 (Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-6-(1-methylcyclopropyl)-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-) 是一种新型苄氨基取代的吡啶并嘧啶酮,可作为 SOS1 抑制剂。
T67748 ROCK-IN-5

ROCK; ERK Cell Cycle/Checkpoint; Cytoskeletal Signaling; MAPK; Stem Cells
ROCK-IN-5(化合物I-B-37)是一种有效的蛋白激酶抑制剂,包括ROCK、ERK、GSK 和AGC。ROCK-IN-5在心脏病、增殖性疾病和神经退行性疾病研究方面具有潜力。
TP1730L β-catenin peptide acetate(265669-37-2 free base)

Others Others
β-catenin peptide acetate(265669-37-2 free base) 是一种由 Kb 呈递的天然存在的自身肽,可非常有效地介导 OT-I 胸腺细胞的阳性选择。
T81373 Proteasome β2c/i-IN-1

Proteasome Proteases/Proteasome; Ubiquitination
Proteasomeβ2c/i-IN-1(compound 37)为针对β2c和β2i亚基的选择性蛋白酶抑制剂。
T125185 Kudinoside I

Kudinoside I 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125185,CAS号为 258343-37-2。
T79355 PRMT4-IN-3

Histone Methyltransferase Chromatin/Epigenetic
PRMT4-IN-3 (compound 56) 作为一种针对 I 类蛋白质精氨酸甲基转移酶 (PRMT) 的抑制剂,对 PRMT4 具有高效抑制作用,表现出对PRMT4(IC50: 37 nM) 和PRMT6(IC50: 253 nM) 的选择性。
TP1971 Pseudo RACK1

Activator of protein kinase C; attached to cell permeabilization Antennapedia domain vector peptide. Consists of peptide derived from the C2 domain of PKC β linked by a disulfide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide i
T38101 Bisucaberin

Bisucaberin is a siderophore and bacterial metabolite that has been found inA. haloplanktisand has anticancer activity.1,2It inhibits the growth of L1210 and 1MC carcinoma cells (IC50s = 9.7 and 12.7 μM, respectively) and sensitizes fibrosarcoma 1023 cells to macrophage-mediated cytolysis. 1.Hou, Z., Raymond, K.N., O’Sullivan, B., et al.A preorganized siderophore: Thermodynamic and structural characterization of alcaligin and bisucaberin, microbial macrocyclic dihydroxamate chelating agentsInorg...
T35814 Urocortin III (human) (trifluoroacetate salt)

Urocortin III is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin II , frog sauvagine, and piscine urotensin I.1 Human urocortin III shares 90, 40, 37, and 21% identity to mouse urocortin III , mouse urocortin II , human urocortin , and mouse urocortin, respectively. Urocortin III selectively binds to type 2 CRF receptors (Kis = 21.7, 13.5, and >100 nM for rat CRF2α, rat CRF2β, and human CRF1, respectively)....

化合物

I-37 free base( 2359690-13-2(free base))
Cat.No: T8721L
Synonym:
Target: Raf
I-37
Cat.No: T8721
Synonym: Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-6-(1-methylcyclopropyl)-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-
Target: Raf
ROCK-IN-5
Cat.No: T67748
Synonym:
Target: ROCK, ERK
β-catenin peptide acetate(265669-37-2 free base)
Cat.No: TP1730L
Synonym:
Target: Others
Proteasome β2c/i-IN-1
Cat.No: T81373
Synonym:
Target: Proteasome
Kudinoside I
Cat.No: T125185
Synonym:
Target:
PRMT4-IN-3
Cat.No: T79355
Synonym:
Target: Histone Methyltransferase
Pseudo RACK1
Cat.No: TP1971
Synonym:
Target:
Bisucaberin
Cat.No: T38101
Synonym:
Target:
Urocortin III (human) (trifluoroacetate salt)
Cat.No: T35814
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T36417 Nargenicin

Antibiotic 47444

Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S. aureus, methicilin resistant S. aureus (MRSA), and M. luteus (MICs = 0.6, 0.3, and 2.5 μg/ml, respectively) over a panel of 11 Gram-positive and Gram-negative bacteria (MICs = >80 μg/ml). [1] It dose-dependently inhibits S. aureus DnaE in the presence of DNase I-activated DNA and E. coli DnaE when used at concentrations of 0.00001-0.1 and 0.01-100 μg/mL, respectively. [2] In murine BV-2 microglial cells, nargenicin (...

天然产物

Nargenicin
Cat.No: T36417
Synonym: Antibiotic 47444
Target:
TargetMol Loading
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