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Cat. No. | Product Name | Target | Signaling Pathways |
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T6858 |
Hydroxyprogesterone caproate
Primolut Depot,Delalutin,Hormofort,己酸孕酮,17α-Hydroxyprogesterone hexanoate,17α-Hydroxyprogesterone caproate |
Autophagy | Autophagy |
Hydroxyprogesterone caproate (Delalutin) 是一种甾体,是一种人工合成的孕激素。 | |||
T40380 |
17α-Hydroxyprogesterone acetate
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Others | Others |
17α-Hydroxyprogesterone acetate 具有孕激素活性和抗炎活性。 | |||
T0977 |
Medrysone
Gimeracil,6α-Methyl-11β-hydroxyprogesterone,6A-甲基-11B-羟孕酮,甲羟松 |
Glucocorticoid Receptor; Others | Endocrinology/Hormones; Others |
Medrysone (6α-Methyl-11β-hydroxyprogesterone) 是局部合成的糖皮质激素,具有代谢、抗炎和抗过敏特性,有潜力用于眼科的眼炎症研究。 | |||
T35665 |
Pregnanetriol
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Pregnanetriol is a metabolite of 17α-hydroxyprogesterone .1,2It is formed from 17α-hydroxyprogesterone by reduction of the C-20 ketone.2Urinary levels of pregnanetriol are elevated in patients with 21-hydroxylase deficiency and congenital adrenal hyperplasia.3,4 1.Kamrath, C., Hartmann, M.F., Boettcher, C., et al.Diagnosis of 21-hydroxylase deficiency by urinary metabolite ratios using gas chromatography-mass spectrometry analysis: Reference values for neonates and infantsJ. Steroid Biochem. Mol... | |||
T31924 |
Gestonorone
17alpha-Hydroxy-19-norprogesterone |
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Gestonorone is steroid progesterone in the 19-nometroprogesterone and 17α -hydroxyprogesterone groups. | |||
T71142 |
Tebuconazole-d9
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Tebuconazole-d9 is intended for use as an internal standard for the quantification of tebuconazole by GC- or LC-MS. Tebuconazole is a triazole fungicide that is active against both seed and foliar fungi. It inhibits 14α-demethylase isolated from U. maydis and S. bicolor with IC50 values of 0.05 and 0.16 nM, respectively. It inhibits the androgenic effect of the androgen receptor agonist DHT (IC20 = 2.89 µM) and is cytotoxic (EC20 = 38.9 µM) in an MDA-kb2 assay. Tebuconazole (50 and 100 mg/kg per... |
Cat. No. | Product Name | Target | Signaling Pathways |
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T1429 |
17α-Hydroxyprogesterone
Hydroxyprogesterone,17-OHP,羟孕酮,17-Hydroxyprogesterone,17α-羟孕酮 |
Estrogen/progestogen Receptor; Progesterone Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism; Others |
17α-Hydroxyprogesterone (17-OHP) 是一种内源性孕激素,其他类固醇激素(包括糖皮质激素,雌激素,和雄激素)生物合成的化学中间体。 | |||
TCA2511 |
11Beta-hydroxyprogesterone
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Sodium Channel | Membrane transporter/Ion channel |
The progesterone derivatives 11 alpha- and 11 beta-hydroxyprogesterone are potent inhibitors of 11 beta-hydroxysteroid dehydrogenase (isoforms 1 and 2) in vitro and can confer mineralocorticoid activity on corticosterone in the rat in vivo. 11beta-Hydroxyprogesterone acts as a mineralocorticoid agonist in stimulating Na+ absorption in mammalian principal cortical collecting duct cells. | |||
T1261 |
Medroxyprogesterone Acetate
Medroxyprogesterone 17-acetate,Provera,Metigestrona,NSC-26386,醋酸甲羟孕酮,Farlutin,安宫黄体酮,Medroxyprogesterone (acetate) |
Glucocorticoid Receptor; Estrogen/progestogen Receptor; Progesterone Receptor; Androgen Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism; Others |
Medroxyprogesterone Acetate (Farlutin) 是广泛使用的合成类固醇,与雄激素,孕酮及糖皮质激素受体均有作用。 | |||
T36915 |
21-Deoxycortisol
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21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11β-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital adrenal hyperplasia that are heterozygous for mutations inCYP2A21, the gene encoding steroid 21-hydroxylase, and have been used as a biomarker for the detection of 21-hydroxylase deficiencies. 1.Fiet, J., Villette, J.-M., Galons, H., et al.The application of a new highly-sensitive... |