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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T6858 Hydroxyprogesterone caproate

Primolut Depot,Delalutin,Hormofort,己酸孕酮,17α-Hydroxyprogesterone hexanoate,17α-Hydroxyprogesterone caproate

Autophagy Autophagy
Hydroxyprogesterone caproate (Delalutin) 是一种甾体,是一种人工合成的孕激素。
T40380 17α-Hydroxyprogesterone acetate

Others Others
17α-Hydroxyprogesterone acetate 具有孕激素活性和抗炎活性。
T0977 Medrysone

Gimeracil,6α-Methyl-11β-hydroxyprogesterone,6A-甲基-11B-羟孕酮,甲羟松

Glucocorticoid Receptor; Others Endocrinology/Hormones; Others
Medrysone (6α-Methyl-11β-hydroxyprogesterone) 是局部合成的糖皮质激素,具有代谢、抗炎和抗过敏特性,有潜力用于眼科的眼炎症研究。
T35665 Pregnanetriol

Pregnanetriol is a metabolite of 17α-hydroxyprogesterone .1,2It is formed from 17α-hydroxyprogesterone by reduction of the C-20 ketone.2Urinary levels of pregnanetriol are elevated in patients with 21-hydroxylase deficiency and congenital adrenal hyperplasia.3,4 1.Kamrath, C., Hartmann, M.F., Boettcher, C., et al.Diagnosis of 21-hydroxylase deficiency by urinary metabolite ratios using gas chromatography-mass spectrometry analysis: Reference values for neonates and infantsJ. Steroid Biochem. Mol...
T31924 Gestonorone

17alpha-Hydroxy-19-norprogesterone

Gestonorone is steroid progesterone in the 19-nometroprogesterone and 17α -hydroxyprogesterone groups.
T71142 Tebuconazole-d9

Tebuconazole-d9 is intended for use as an internal standard for the quantification of tebuconazole by GC- or LC-MS. Tebuconazole is a triazole fungicide that is active against both seed and foliar fungi. It inhibits 14α-demethylase isolated from U. maydis and S. bicolor with IC50 values of 0.05 and 0.16 nM, respectively. It inhibits the androgenic effect of the androgen receptor agonist DHT (IC20 = 2.89 µM) and is cytotoxic (EC20 = 38.9 µM) in an MDA-kb2 assay. Tebuconazole (50 and 100 mg/kg per...

化合物

Hydroxyprogesterone caproate
Cat.No: T6858
Synonym: Primolut Depot,Delalutin,Hormofort,己酸孕酮,17α-Hydroxyprogesterone hexanoate,17α-Hydroxyprogesterone caproate
Target: Autophagy
17α-Hydroxyprogesterone acetate
Cat.No: T40380
Synonym:
Target: Others
Medrysone
Cat.No: T0977
Synonym: Gimeracil,6α-Methyl-11β-hydroxyprogesterone,6A-甲基-11B-羟孕酮,甲羟松
Target: Glucocorticoid Receptor, Others
Pregnanetriol
Cat.No: T35665
Synonym:
Target:
Gestonorone
Cat.No: T31924
Synonym: 17alpha-Hydroxy-19-norprogesterone
Target:
Tebuconazole-d9
Cat.No: T71142
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T1429 17α-Hydroxyprogesterone

Hydroxyprogesterone,17-OHP,羟孕酮,17-Hydroxyprogesterone,17α-羟孕酮

Estrogen/progestogen Receptor; Progesterone Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism; Others
17α-Hydroxyprogesterone (17-OHP) 是一种内源性孕激素,其他类固醇激素(包括糖皮质激素,雌激素,和雄激素)生物合成的化学中间体。
TCA2511 11Beta-hydroxyprogesterone

Sodium Channel Membrane transporter/Ion channel
The progesterone derivatives 11 alpha- and 11 beta-hydroxyprogesterone are potent inhibitors of 11 beta-hydroxysteroid dehydrogenase (isoforms 1 and 2) in vitro and can confer mineralocorticoid activity on corticosterone in the rat in vivo. 11beta-Hydroxyprogesterone acts as a mineralocorticoid agonist in stimulating Na+ absorption in mammalian principal cortical collecting duct cells.
T1261 Medroxyprogesterone Acetate

Medroxyprogesterone 17-acetate,Provera,Metigestrona,NSC-26386,醋酸甲羟孕酮,Farlutin,安宫黄体酮,Medroxyprogesterone (acetate)

Glucocorticoid Receptor; Estrogen/progestogen Receptor; Progesterone Receptor; Androgen Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism; Others
Medroxyprogesterone Acetate (Farlutin) 是广泛使用的合成类固醇,与雄激素,孕酮及糖皮质激素受体均有作用。
T36915 21-Deoxycortisol

21-Deoxycortisol is a corticosteroid metabolite of 17-hydroxyprogesterone produced in the adrenal glandvia11-hydroxylation by 11β-hydroxylase.1,2Serum levels of 21-deoxycortisol are elevated in patients with congenital adrenal hyperplasia that are heterozygous for mutations inCYP2A21, the gene encoding steroid 21-hydroxylase, and have been used as a biomarker for the detection of 21-hydroxylase deficiencies. 1.Fiet, J., Villette, J.-M., Galons, H., et al.The application of a new highly-sensitive...

天然产物

17α-Hydroxyprogesterone
Cat.No: T1429
Synonym: Hydroxyprogesterone,17-OHP,羟孕酮,17-Hydroxyprogesterone,17α-羟孕酮
Target: Estrogen/progestogen Receptor, Progesterone Receptor, Endogenous Metabolite
11Beta-hydroxyprogesterone
Cat.No: TCA2511
Synonym:
Target: Sodium Channel
Medroxyprogesterone Acetate
Cat.No: T1261
Synonym: Medroxyprogesterone 17-acetate,Provera,Metigestrona,NSC-26386,醋酸甲羟孕酮,Farlutin,安宫黄体酮,Medroxyprogesterone (acetate)
Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, Androgen Receptor, Endogenous Metabolite
21-Deoxycortisol
Cat.No: T36915
Synonym:
Target:
TargetMol Loading
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