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Targets Recommended: HIF

2

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T36711 FM19G11

FM19G11,HIF-1alpha/2alpha Inhibitor

HIF Angiogenesis; Chromatin/Epigenetic
FM19G11 是一种低氧诱导因子 (HIF) α-亚基抑制剂(在低氧诱导的荧光素酶试验中 IC50 为 80 nM)。
T3494 LW6

HIF-1α inhibitor,CAY10585,LW8

Apoptosis; Dehydrogenase; HIF/HIF Prolyl-Hydroxylase; HIF Angiogenesis; Apoptosis; Chromatin/Epigenetic; Metabolism
LW6 (HIF-1α inhibitor) 是一种新型 HIF-1抑制剂,IC50值为 4.4 μM。它降低 HIF-1α蛋白表达,但不影响 HIF-1β 表达。

化合物

FM19G11
Cat.No: T36711
Synonym: FM19G11,HIF-1alpha/2alpha Inhibitor
Target: HIF
LW6
Cat.No: T3494
Synonym: HIF-1α inhibitor,CAY10585,LW8
Target: Apoptosis, Dehydrogenase, HIF/HIF Prolyl-Hydroxylase, HIF
Cat. No. Product Name Species Expression System
TMPY-01709 HIF-1 alpha Protein, Human, Recombinant (His)

bHLHe78,HIF-1 α,hypoxia inducible factor 1, alpha s...

Human E. coli
HIF-1 alpha, also known as HIF1A, contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. It is one of the two subunits of Hypoxia-inducible factor-1 (HIF1). HIF1 is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has...

重组蛋白

HIF-1 alpha Protein, Human, Recombinant (His)
Cat.No: TMPY-01709
Species: Human
Expression System: E. coli
TargetMol Loading
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