Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03361 |
Pleiotrophin/PTN Protein, Human, Recombinant
HBNF,HBGF8,pleiotrophin,HARP,NEGF1 |
Human | Baculovirus-Insect Cells |
HB-GAM belongs to the pleiotrophin family. During embryonic and early postnatal development, HB-GAM is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, gut and bone. While in the adult central nervous system, it is expressed in an activity-dependent manner in the hippocampus where it can suppress long term potentiation induction. HB-GAM has a low expression in other areas of the adult brain, but it can be induced by ischemic ins... | |||
TMPY-03577 |
Pleiotrophin/PTN Protein, Mouse, Recombinant
HBGF-8,HBBN,HBNF,HB-GAM,pleiotrophin,Osf-1... |
Mouse | Baculovirus-Insect Cells |
HB-GAM belongs to the pleiotrophin family. During embryonic and early postnatal development, HB-GAM is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, gut and bone. While in the adult central nervous system, it is expressed in an activity-dependent manner in the hippocampus where it can suppress long term potentiation induction. HB-GAM has a low expression in other areas of the adult brain, but it can be induced by ischemic ins... | |||
TMPY-00005 |
FGF-8a Protein, Human, Recombinant
fibroblast growth factor 8 (androgen-induced),FGF-<... |
Human | E. coli |
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac... | |||
TMPY-06986 |
FGF-8b Protein, Human, Recombinant
NEWENTRY,fibroblast growth factor 8 (androgen-induc... |
Human | E. coli |
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac... | |||
TMPY-02850 |
Pleiotrophin/PTN Protein, Mouse, Recombinant (hFc)
Osf-1,HB-GAM,HBGF-8,HBBN,pleiotrophin,OSF,... |
Mouse | HEK293 |
HB-GAM belongs to the pleiotrophin family. During embryonic and early postnatal development, HB-GAM is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, gut and bone. While in the adult central nervous system, it is expressed in an activity-dependent manner in the hippocampus where it can suppress long term potentiation induction. HB-GAM has a low expression in other areas of the adult brain, but it can be induced by ischemic ins... | |||
TMPJ-01051 |
Pleiotrophin/PTN Protein, Mouse, Recombinant (His)
HBGF-8,OSF-1,PTN,HBBM,Pleiotrophin,Heparin... |
Mouse | Human Cells |
Pleiotrophin (PTN) is a secreted, strongly heparinbinding, developmentally regulated cytokine. PTN is a highly conserved protein,Human, mouse, rat, canine, porcine, equine and bovine PTN share 98% aa sequence identity or greater. PTN and midkine share 50% amino acid (aa) sequence identity, share some functions, and constitute a family. During development, PTN is involved in development of brain, bone, and organs undergoing branching morphogenesis. PTN causes PTPRB dimerization and inactivates it... |