Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN4168 |
Grifolin
|
Others | Others |
Grifolin has anti-cancer effects, it induces apoptosis and promotes cell cycle arrest in the A2780 human ovarian cancer cell line via inactivation of the ERK1/2 and Akt pathways; it enhances the differentiation and proliferation of oligodendrocyte precurs | |||
TN4169 | Grifolin monomethyl ether | Others | Others |
Grifolin monomethyl ether 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4169,CAS号为 64432-04-8。 | |||
TN3743 |
Cyclogrifolin
|
Others | Others |
Cyclogrifolin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3743,CAS号为 1660156-04-6。 | |||
TN2654 | 17-Hydroxy-18-dehydroneogrifolin | Others | Others |
17-Hydroxy-18-dehydroneogrifolin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2654,CAS号为 1630936-42-3。 | |||
TN4637 |
Neogrifolin
|
PARP; GSK-3; Akt; Caspase | Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling; Proteases/Proteasome; Stem Cells |
Neogrifolin is a potential candidate for osteosarcoma, it can induce concentration- and time-dependent suppression of proliferation and induce apoptosis in U2OS and MG63 osteosarcoma cell lines; it exhibits inhibitory activity against nitric oxide (NO) production stimulated by lipopolysaccharide (LPS) in RAW 264.7 cells with the IC50value of 23.3 microM. Neogrifolin possesses antimicrobial activities against Bacillus cereus and Enterococcus faecalis, the MIC values of 20 and 0.5 microg/mL, respe... |