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Search Results for " glutamate decarboxylase "

Targets Recommended: GluR

抑制剂 & 化合物

天然产物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T5884	Chelidamic acid 4-氧代-1,4-二氢-2,6-吡啶二甲酸,白屈氨酸	GluR	Neuroscience
	Chelidamic acid 是一种有效的谷氨酸脱羧酶抑制剂(Ki:33 μM)，也是含有吡喃骨架的杂环有机酸，与金属离子有良好的配位能力。
T37190	L-Allylglycine	Dehydrogenase; GABA Receptor	Membrane transporter/Ion channel; Metabolism; Neuroscience
	L-Allylglycine 是 GABA 合成酶（谷氨酸脱羧酶）的有效抑制剂。
T7622L	Gabazine free base Chebi:34968,SR95531,C13796,J331.170H,SR 95531
	Gabazine free base is a specific antagonist of the GABA receptor. It does not affect GABA-transaminase or glutamate-decarboxylase activities.
T25052	Allylglycine
	Allylglycine is a glutamate decarboxylase inhibitor and a GAMMA-AMINOBUTYRIC ACID antagonist. It is used to induce convulsions in experimental animals.
T80218	GAD65(247-266) epitope TFA	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	GAD65(247-266) epitope TFA 为T细胞表位，与I-Ag7（I型糖尿病相关分子）竞争性结合，亲和力较低。该表位源自胰岛抗原，GAD65 是谷氨酸脱羧酶 65，涉及将谷氨酸转换为γ-氨基丁酸（GABA）。

化合物

Chelidamic acid

Cat.No: T5884

Synonym: 4-氧代-1,4-二氢-2,6-吡啶二甲酸,白屈氨酸

Target: Dehydrogenase, GABA Receptor

Gabazine free base

Cat.No: T7622L

Synonym: Chebi:34968,SR95531,C13796,J331.170H,SR 95531

GAD65(247-266) epitope TFA

Cat.No: T80218

Synonym:

Target: GABA Receptor

Cat. No.	Product Name	Target	Signaling Pathways
T4913	Maleic acid	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	Maleic Acid 是大肠杆菌和单核细胞增生李斯特菌的谷氨酸脱羧酶抑制剂。
T5558	Chelidonic acid Jervaic acid,Jerva acid,白屈菜酸,γ-Pyrone-2,6-dicarboxylic acid	NF-κB; Caspase	Apoptosis; NF-κB; Proteases/Proteasome
	Chelidonic acid (Jervaic acid) 是从白屈菜中分到的酸类物质，用作温和的镇痛剂、抗菌剂和中枢神经系统镇静剂。它是谷氨酸脱羧酶抑制剂，Ki 值为 1.2 μM。它可能通过抑制 NF-κB 和caspase-1来降低 IL-6 的产生抗炎作用。

天然产物

Maleic acid

Cat.No: T4913

Synonym:

Target: Endogenous Metabolite, Antibacterial

Chelidonic acid

Cat.No: T5558

Synonym: Jervaic acid,Jerva acid,白屈菜酸,γ-Pyrone-2,6-dicarboxylic acid

Target: NF-κB, Caspase

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04699	GAD65 Protein, Human, Recombinant (GST) glutamate decarboxylase 2 (pancreatic isle...	Human	Baculovirus Insect Cells
	GAD65 Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 92.6 kDa and the accession number is Q05329.
TMPJ-00855	GLUL Protein, Human, Recombinant (His) GLUL,GS,Glutamine Synthetase,Glutamate-Ammonia Liga...	Human	E. coli
	Glutamine Synthetase reglutes intracellular concentration of glutamate. Glutamine Synthetase catalyzes the synthesis of glutamine from glutamate and ammonia. Glutamine is an important source of energy and that takes part in cell prolifetation, inhibition of apoptosis, and cell signaling. Glutamine Synthetase is expressed during early fetal stages, and has a role in maintaining body PH by removing ammonia from circulation. Mutations in the GLUL gene are related to congenital glutamine deficiency.
TMPY-02091	GAD67 Protein, Human, Recombinant (His) SCP,CPSQ1,glutamate decarboxylase 1 (brain...	Human	Baculovirus Insect Cells
	Glutamate decarboxylase 1, also known as 67 kDa glutamic acid decarboxylase, Glutamate decarboxylase 67 kDa isoform and GAD1, is a member of thegroup II decarboxylase family. GAD1 is expressed in benign and malignant prostatic tissue and may serve as a highly prostate-specific tissue biomarker. GAD1 isoform3 is expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain. Tissue-specific markers are useful for identification of tumour type ...
TMPY-03515	GAD65 Protein, Mouse, Recombinant glutamate decarboxylase 2 (pancreatic isle...	Mouse	Baculovirus Insect Cells
	GAD65 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 65.4 kDa and the accession number is P48320.
TMPY-01590	GAD65 Protein, Mouse, Recombinant (His & GST) glutamate decarboxylase 2 (pancreatic isle...	Mouse	Baculovirus Insect Cells
	GAD65 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 93 kDa and the accession number is P48320.