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20

抑制剂 & 化合物

16

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T20154	Geranyl butyrate NSC 46146,NSC46146,NSC-46146
	Geranyl butyrate is an agent of biochemical.
T35589	Geranyl pyrophosphate triammonium
	Geranyl pyrophosphate is an intermediate in the mevalonate pathway. It is formed from dimethylallyl pyrophosphate and isopentenyl pyrophosphate by geranyl pyrophosphate synthase. Geranyl pyrophosphate is used in the biosynthesis of farnesyl pyrophosphate , geranylgeranyl pyrophosphate , cholesterol, terpenes, and terpenoids.
T73807	Geranyl diphosphate
	Geranyl diphosphate 是IBP(类异戊二烯生物合成途径)的关键中间体，在细胞代谢中扮演至关重要的角色，主要负责甾醇和非甾醇类异戊二烯的生成。
T125251	8-Geranyl-7-hydroxycoumarin
	8-Geranyl-7-hydroxycoumarin 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125251，CAS号为 23660-05-1。
T126191	5'-Geranyl-5,7,2',4'-tetrahydroxyflavone
	5'-Geranyl-5,7,2',4'-tetrahydroxyflavone 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T126191。
T125994	3-Geranyl-4-hydroxy-5-prenylbenzoic acid
	3-Geranyl-4-hydroxy-5-prenylbenzoic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125994，CAS号为 135743-12-3。
T12452	Digeranyl bisphosphonate DGBP	Rho; Ras	Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
	Digeranyl bisphosphonate (DGBP) 是一种有效的香叶基焦磷酸香叶酯 (GGPP) 合酶抑制剂，对 Rac1 的香叶基焦磷酸化有抑制作用。Digeranyl bisphosphonate 诱导细胞发生自噬却不诱导细胞凋亡。
T40781L	Geranylgeranyl pyrophosphate tetrabutylammonium(1:1.5)	Others	Others
	(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-yl dihydrogen diphosphate,tetrabutylammonium(1:1.5) 是紫杉二烯，如紫杉醇，的常见前体。
T40781L1	Geranylgeranyl pyrophosphate tetrabutylammonium(1：2) Geranylgeranyl pyrophosphate tetrabutylammonium（1：2）(6699-20-3 Free base)	Others	Others
	Geranylgeranyl pyrophosphate tetrabutylammonium(1：2)是甲羟戊酸途径产生内源性胆固醇和中间体之一。Geranylgeranyl pyrophosphate tetrabutylammonium(1：2) 香叶基香叶基焦磷酸三铵是二萜类化合物的常见前体，例如紫杉醇，可用于癌症研究。
T8368	Geranylacetone(Z/E) 6,10-二甲基-5,9-十一双烯-2-酮,Dihydropseudoionone	Others	Others
	Geranylacetone(Z/E) (Dihydropseudoionone) 是一种天然存在的化合物，存在于许多植物的精油中，包括迷迭香、薰衣草和茉莉花。它具有抗氧化、抗炎和抗微生物的特性。
T40781	Geranylgeranyl pyrophosphate
	Geranylgeranyl pyrophosphate, a key metabolite in protein geranylgeranylation, serves as the universal precursor for diterpenoids, such as Paclitaxel. Its role in cancer research stems from this critical function.
T129912	7-Geranyloxy-1,3-dihydroxyxanthone
	7-Geranyloxy-1,3-dihydroxyxanthone 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T129912。
T36668	Geranylgeranoic Acid
	Geranylgeranoic acid (GGA) is an isoprenoid that has been found inS. chinensisand has anticancer activity.1It induces apoptosis in Huh7 and PLC/PRF/5 human hepatoma cells and MLE-10 transformed mouse hepatocytes, but not primary mouse hepatocytes, when used at concentrations ranging from 1 to 20 μM. GGA (10 μM) induces apoptosis in Huh7 cellsvialoss of the mitochondrial membrane potential and activation of interleukin-1β-converting enzyme (ICE) and cysteine protease precursor 32 (CPP32).2It also...
T124933	5,7,2',4'-Tetrahydroxy-3-geranylflavone
	5,7,2',4'-Tetrahydroxy-3-geranylflavone 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124933。
T83926	S-Geranylgeranyl-L-glutathione GGG
	S-Geranylgeranyl-L-glutathione是孤儿G蛋白偶联受体（GPCR）P2RY8的配体。该化合物在100 nM浓度下，选择性地诱导P2RY8而非鞘氨醇-1-磷酸受体2（S1P2）、GPR55、半胱氨酸白三烯受体1（CysLT1 receptor）以及CysLT2 receptor的内吞作用。在10 nM浓度下，S-Geranylgeranyl-L-glutathione抑制了表达P2RY8的WEHI-231 B细胞淋巴瘤细胞和分离的人扁桃体生发中心B细胞由趋化因子（C-X-C motif）配体12（CXCL12）诱导的迁移。
T37693	N-acetyl-S-geranylgeranyl-L-Cysteine
	N-acetyl-S-geranylgeranyl-L-Cysteine is a synthetic substrate for the isoprenylated protein methyltransferase (also known as S-adenosylmethionine-dependent methyltransferase). Because it is able to serve as a substrate for the methyltransferase, it effectively functions as an inhibitor of methylation of endogenous isoprenylated proteins.
T36863	Geranylgeranyl Pyrophosphate (ammonium salt) Geranylgeranyl Pyrophosphate (ammonium salt),GGPP
	Geranylgeranyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway derived directly from farnesyl pyrophosphate and used in the biosynthesis of terpenes and terpenoids.[1] It is also serves as a substrate in the prenylation of a variety of critical intracellular proteins including small GTPases.[2] This post-translational modification is necessary for correct localization of proteins to intracellular membranes for proper functionality and has become a focus of anticancer drug disco...
T78081	Farnesyl Pyrophosphate ammonium Farnesyl diphosphate ammonium
	Farnesyl pyrophosphate ammonium salt为15碳类异戊二烯代谢中间体，源自MVA途径，兼具TRPM2激动剂功能，能够触发TRPM2通道开放并促进离子流入细胞。它亦是胆固醇合成、泛醌合成、蛋白质法尼基化修饰以及GGPP合成的关键底物。
T61945	hGGPPS-IN-1
	hGGPPS-IN-1 是 C-2 取代的噻吩并嘧啶基双膦酸盐 (C2-ThP-BPs) 的类似物，对人类香叶基香叶基焦磷酸合成酶 (hGGPPS) 具有有效的抑制作用。hGGPPS-IN-1 可选择性诱导多发性骨髓瘤 (MM) 细胞凋亡 (apoptosis)。hGGPPS-IN-1在体内表现出抗骨髓瘤活性。
T73755	Farnesyl pyrophosphate
	Farnesyl pyrophosphate (Farnesyl diphosphate) 是一种由15个碳原子组成的异戊二烯类化合物，作为甲羟戊酸 (MVA) 途径的关键代谢中间体。它充当TRPM2 (TRP Channel) 的激动剂，通过激活并打开TRPM2通道，促使离子流入细胞。此外，Farnesyl pyrophosphate 在胆固醇合成、泛醌合成、蛋白质法尼基化修饰以及香叶基-香叶基焦磷酸 (GGPP) 合成过程中扮演着至关重要的底物角色。

化合物

Geranyl butyrate

Cat.No: T20154

Synonym: NSC 46146,NSC46146,NSC-46146

Geranyl pyrophosphate triammonium

Cat.No: T35589

Geranyl diphosphate

Cat.No: T73807

8-Geranyl-7-hydroxycoumarin

Cat.No: T125251

5'-Geranyl-5,7,2',4'-tetrahydroxyflavone

Cat.No: T126191

3-Geranyl-4-hydroxy-5-prenylbenzoic acid

Cat.No: T125994

Digeranyl bisphosphonate

Cat.No: T12452

Synonym: DGBP

Target: Rho, Ras

Geranylgeranyl pyrophosphate tetrabutylammonium(1:1.5)

Cat.No: T40781L

Target: Others

Geranylgeranyl pyrophosphate tetrabutylammonium(1：2)

Cat.No: T40781L1

Synonym: Geranylgeranyl pyrophosphate tetrabutylammonium（1：2）(6699-20-3 Free base)

Target: Others

Geranylacetone(Z/E)

Cat.No: T8368

Synonym: 6,10-二甲基-5,9-十一双烯-2-酮,Dihydropseudoionone

Target: Others

Geranylgeranyl pyrophosphate

Cat.No: T40781

7-Geranyloxy-1,3-dihydroxyxanthone

Cat.No: T129912

Geranylgeranoic Acid

Cat.No: T36668

5,7,2',4'-Tetrahydroxy-3-geranylflavone

Cat.No: T124933

S-Geranylgeranyl-L-glutathione

Cat.No: T83926

Synonym: GGG

N-acetyl-S-geranylgeranyl-L-Cysteine

Cat.No: T37693

Geranylgeranyl Pyrophosphate (ammonium salt)

Cat.No: T36863

Synonym: Geranylgeranyl Pyrophosphate (ammonium salt),GGPP

Farnesyl Pyrophosphate ammonium

Cat.No: T78081

Synonym: Farnesyl diphosphate ammonium

Cat.No: T61945

Farnesyl pyrophosphate

Cat.No: T73755

Cat. No.	Product Name	Target	Signaling Pathways
T3239	Geranyl Tiglate Geranium oil,tiglic acid geranyl ester,洋绣球,天竺葵油	Others	Others
	Geranyl Tiglate (tiglic acid geranyl ester) 是最重要的天然香料之一。
T5607	Geranyl acetate	Apoptosis; Others	Apoptosis; Others
	Geranyl acetate 是一种由香叶醇衍生而来的无环单萜烯酯，可诱导细胞凋亡。它具有香味，被广泛用于化妆品行业。
TN1252	3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone	Others	Others
	3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone is a natural product from Morus alba.
TN4129	Geranyl ferulate	Others	Others
	Geranyl ferulate 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4129，CAS号为 1206615-69-1。
TCP2830	Neryl acetate Nerol acetate,Acetic acid neryl ester,(Z)-3,7-二甲基-2,6-辛二烯-1-醇乙酸酯,cis-Geranyl acetate	Others	Others
	Neryl acetate (Acetic acid neryl ester) 是一种分离自柑桔油中的物质。
TN2759	2-Geranyl-4-isobutyrylphloroglucinol	Others	Others
	2-Geranyl-4-isobutyrylphloroglucinol 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN2759，CAS号为 72008-03-8。
TN2935	3-Geranyl-4-methoxybenzoic acid	Others	Others
	3-Geranyl-4-methoxybenzoic acid exhibits stronger inhibition effect on the activation of hyaluronidase than that of tranilast.
TN1343	8-Geranyloxypsoralen 8-香叶草氧基补骨脂素	Anti-infection; P450; BACE	Metabolism; Microbiology/Virology; Neuroscience
	8-Geranyloxypsoralen 是一种呋喃香豆素，分离自葡萄柚，是 P450 3A4 的有效抑制剂(IC50:3.93 μM)。
TN6714	Geranylgeraniol FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,香叶基香叶醇,CJ-24095	Apoptosis	Apoptosis
	Geranylgeraniol (FT0626663) 是一种类异戊二烯，存在于水果、蔬菜和谷物中，包括大米。 Geranylgeraniol (FT0626663) 抑制生长并诱导各种肿瘤细胞的凋亡。 Geranylgeraniol (FT0626663) 保护单核细胞免受他汀类药物诱导的细胞毒性并抑制分枝杆菌的生长。
TN3170	6-Geranylnaringenin	Others	Others
	6-Geranylnaringenin is a natural product from Humulus lupulus.
T10195	7-O-Geranylscopoletin 7-Geranyloxy-6-methoxycoumarin	Others	Others
	7-O-Geranylscopoletin is a natural coumarin from the root of Atalantia monophylla. Various parts of this plant have been used for folk medicine for several purposes such as the treatment of chronic rheumatism, antispasmodic, paralysis, hemiplegia, and sti
T7920	Geranylacetone	Others	Others
	Geranylacetone 具有锥虫抑制活性，可以通过抑制唾液酸酶和/或保护寄生虫引起的肝脾肿大来保护动物免受刚果锥虫引起的贫血。
TN3277	8-Geranyloxy-5,7-dimethoxycoumarin	Others	Others
	8-Geranyloxy-5,7-dimethoxycoumarin是一种天然产物，属于芸香科飞龙掌血属，其产品编号为 TN3277，CAS号为 1228175-65-2。8-Geranyloxy-5,7-dimethoxycoumarin可用作对照参考。
TN3085	5,7,3',4'-Tetrahydroxy-3-methoxy-8-geranylflavone	Others	Others
	5,7,3',4'-Tetrahydroxy-3-methoxy-8-geranylflavone is a natural product from Broussonetia papyrifera.
TN3225	7-Geranyloxy-5-methoxycoumarin	Others	Others
	7-Geranyloxy-5-methoxycoumarin 是一种天然存在的化合物，存在于许多植物中，包括红枫树的树皮。它已被证明具有抗炎、抗氧化和抗肿瘤的特性。
TN4687	O-Geranylconiferyl alcohol	Others	Others
	O-Geranylconiferyl alcohol是一种天然产物，属于芸香科花椒属，其产品编号为 TN4687，CAS号为 129350-09-0。O-Geranylconiferyl alcohol可用作对照参考。

天然产物

Geranyl Tiglate

Cat.No: T3239

Synonym: Geranium oil,tiglic acid geranyl ester,洋绣球,天竺葵油

Target: Others

Geranyl acetate

Cat.No: T5607

Target: Apoptosis, Others

3'-Geranyl-3-prenyl-2',4',5,7-tetrahydroxyflavone

Cat.No: TN1252

Target: Others

Geranyl ferulate

Cat.No: TN4129

Target: Others

Cat.No: TCP2830

Synonym: Nerol acetate,Acetic acid neryl ester,(Z)-3,7-二甲基-2,6-辛二烯-1-醇乙酸酯,cis-Geranyl acetate

Target: Others

2-Geranyl-4-isobutyrylphloroglucinol

Cat.No: TN2759

Target: Others

3-Geranyl-4-methoxybenzoic acid

Cat.No: TN2935

Target: Others

8-Geranyloxypsoralen

Cat.No: TN1343

Synonym: 8-香叶草氧基补骨脂素

Target: Anti-infection, P450, BACE

Geranylgeraniol

Cat.No: TN6714

Synonym: FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,香叶基香叶醇,CJ-24095

Target: Apoptosis

6-Geranylnaringenin

Cat.No: TN3170

Target: Others

7-O-Geranylscopoletin

Cat.No: T10195

Synonym: 7-Geranyloxy-6-methoxycoumarin

Target: Others

Geranylacetone

Cat.No: T7920

Target: Others

8-Geranyloxy-5,7-dimethoxycoumarin

Cat.No: TN3277

Target: Others

5,7,3',4'-Tetrahydroxy-3-methoxy-8-geranylflavone

Cat.No: TN3085

Target: Others

7-Geranyloxy-5-methoxycoumarin

Cat.No: TN3225

Target: Others

O-Geranylconiferyl alcohol

Cat.No: TN4687

Target: Others

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