Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0702 |
Gabapentin
Neurontin,Gabapentine,加巴喷丁,Aclonium |
Calcium Channel; GABA Receptor | Membrane transporter/Ion channel; Metabolism; Neuroscience |
Gabapentin (Neurontin) 是GABA 类似物,是一种抗癫痫药,可用于缓解神经性疼痛。 | |||
T6507 |
Gabapentin hydrochloride
加巴喷丁盐酸盐,Neurontin HCl,Gabapentin HCl |
Calcium Channel; GABA Receptor | Membrane transporter/Ion channel; Metabolism; Neuroscience |
Gabapentin hydrochloride (Neurontin HCl) 是GABA 类似物,可用于缓解神经性疼痛。 | |||
T15366 |
Gabapentin enacarbil
XP-13512,加巴喷丁酯 |
Others; Calcium Channel | Membrane transporter/Ion channel; Metabolism; Others |
Gabapentin enacarbil (XP-13512) 是抗惊厥和镇痛药物加巴喷丁的前药。Gabapentin enacarbil 提供持续剂量比例的 Gabapentin 暴露和可预测的生物利用度。 | |||
T30188 |
Atagabalin
PD 0200390,PD-0200390,PD0200390 |
||
Atagabalin, also known as PD 0200390, is a gabamimetic agent under development for the treatment for insomnia. Atagabalin is related to gabapentin, which similarly binds to the α2δ calcium channels (1 and 2). It was discontinued following unsatisfactory t | |||
T28346 |
PD-217014 HCl
PD 217014,PD217014,PD-217,014,PD-217014 |
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PD-217014 is a GABA analog. It inhibits (3)H-gabapentin binding to alpha(2)delta subunit of voltage-gated calcium channels in a concentration-dependent manner (K(i) = 18 nmol/l). PD-217014 possesses visceral analgesic activity. | |||
T71206 |
Tiagabine-d6 hydrochloride
|
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Tiagabine-d6 is intended for use as an internal standard for the quantification of tiagabine by GC- or LC-MS. Tiagabine is an inhibitor of GABA transporter 1. It inhibits seizures induced by DMCM in mice. Tiagabine reduces allodynia in a rodent model of neuropathic pain when used at a dose of 72.8 µmol/kg, and it acts synergistically with gabapentin to delay pain responses in mice in the hot plate test. Formulations containing tiagabine have been used as adjunctive therapies in the treatment of ... |