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Targets Recommended: Platelet aggregation Microtubule Associated NO Synthase

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T62899	Tau-aggregation and neuroinflammation-IN-1	Microtubule Associated; NO Synthase	Cytoskeletal Signaling; Immunology/Inflammation
	Tau-aggregation and neuroinflammation-IN-1 是一种有效的 Tau 蛋白聚集体抑制剂，对 AcPHF6 和全长 tau 蛋白聚集体显示出显著的抑制活性。Tau-aggregation and neuroinflammation-IN-1具有抗炎活性且可减少 NO 释放。Tau-aggregation and neuroinflammation-IN-1 对 LSP 刺激的 BV2 细胞具有低细胞毒性。Tau-aggregation and neuroinflammation-IN-1 可逆转冈田酸诱导的大鼠记忆障碍。
T39781	Aβ/tau aggregation-IN-1
	Aβ/tau aggregation-IN-1 is a potent inhibitor of Aβ 1-42 β-sheet formation and tau aggregation. It exhibits K D values of 160 μM and 337 μM with Aβ 1-42 and tau, respectively. Additionally, Aβ/tau aggregation-IN-1 can penetrate the blood-brain barrier efficiently.
T78173	Aβ/tau aggregation-IN-3
	Aβ/tau aggregation-IN-3为一种高效的抗Aβ聚集剂，经Aβ-硫黄素T (Aβ-ThT) 聚集测定显示，其半抑制浓度(IC50)为0.85 μM，表现出显著的抗淀粉样蛋白活性。
T79038	Tau protein aggregation-IN-1
	Tau protein aggregation-IN-1（化合物 0c）是一种针对Tau protein聚集的抑制剂。该化合物主要应用于研究蛋白质折叠障碍类疾病，包括阿尔茨海默病、痴呆、帕金森病、亨廷顿舞蹈病及基于朊病毒引起的海绵状脑病。
T64238	Aβ1–42 aggregation inhibitor 1
	Aβ1-42 aggregation inhibitor 1 抑制乙酰胆碱酯酶 AChE 和丁酰胆碱酯酶 BuChE 的 IC50值分别为 2.64 μM 和 1.29 μM。Aβ1-42 aggregation inhibitor 1 是一种可以自身介导的Aβ1-42聚集抑制剂，在浓度为 25 μM 抑制 51.29%。Aβ1-42 aggregation inhibitor 1 可用于抗阿尔兹海默症的研究。
T74811	tau/Aβ40 aggregation-IN-1
	tau/Aβ40 aggregation-IN-1 (Compound 20) 是一种tau 和Aβ40聚集抑制剂，其IC50分别为 1.8 μM 和 1.3 μM 。
T63481	Tau-aggregation-IN-1
	Tau-aggregation-IN-1 是一种 dopamine D2和 D3受体激动剂，也是 tau441 蛋白聚合抑制剂 (IC50: 21 μM)。

化合物

Tau-aggregation and neuroinflammation-IN-1

Cat.No: T62899

Synonym:

Target: Microtubule Associated, NO Synthase

Aβ/tau aggregation-IN-1

Cat.No: T39781

Synonym:

Target:

Aβ/tau aggregation-IN-3

Cat.No: T78173

Synonym:

Target:

Tau protein aggregation-IN-1

Cat.No: T79038

Synonym:

Target:

Aβ1–42 aggregation inhibitor 1

Cat.No: T64238

Synonym:

Target:

tau/Aβ40 aggregation-IN-1

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04742	BST2 Protein, Mouse, Recombinant (His) Bst-2,GREG,bone marrow stromal cell antigen 2,C8704...	Mouse	HEK293 Cells
	BST2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.6 kDa and the accession number is Q8R2Q8.
TMPY-02674	BST2 Protein, Mouse, Recombinant (hFc) 2310015I10Rik,bone marrow stromal cell antigen 2,C87040,CD31...	Mouse	HEK293 Cells
	BST2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40 kDa and the accession number is Q8R2Q8.
TMPH-00037	Leukotoxin Protein, Aggregatibacter actinomycetemcomitans, Recombinant (His)	Aggregatibacter actinomycetemcomitans	P. pastoris (Yeast)
	Virulence factor that plays an important role in immune evasion. Lyses human lymphocytes and monocytes. Binds to the LFA-1 integrin on the surface of the host cell and to cholesterol-containing membranes, which probably results in large LtxA-LFA-1 clusters in lipid rafts. Shows also beta-hemolytic activity on certain types of growth media. Leukotoxin Protein, Aggregatibacter actinomycetemcomitans, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 38.3 kD...