21
33
17
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T27420 |
GMA-839
|
||
GMA-839 is a selective modulator of gamma-aminobutyric acid(A) receptors. | |||
T13510 |
Sigma-LIGAND-1
|
Sigma receptor | GPCR/G Protein |
Sigma-LIGAND-1 是一种选择性 sigma 受体配体,在 DTG 和 PPP 位点的 IC50 分别为 16 nM,19 nM。Sigma-LIGAND-1 对多巴胺 D2 受体的 Ki 为 4000 nM。 | |||
T84308 |
(24R)-Stigmastane-3β,5α,6α-triol
|
||
T12910 |
Sigma-1 receptor antagonist 1
|
Sigma receptor | GPCR/G Protein |
Sigma-1 receptor antagonist 1 是一种有效、特异性的 sigma-1 受体拮抗剂。 Sigma-1 receptor antagonist 1 具有抗神经性疼痛活性,可用于治疗神经性疼痛研究。 | |||
T12911 |
Sigma-1 receptor antagonist 2
|
Sigma receptor | GPCR/G Protein |
Sigma-1 receptor antagonist 2 是有效的sigma 1受体选择性拮抗剂,与 σ1 和 σ2 受体结合的Ki 分别为 3.88 和 1288 nM。 | |||
T12912 |
Sigma-1 receptor antagonist 3
|
Sigma receptor; HER | Angiogenesis; GPCR/G Protein; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Sigma-1 receptor antagonist 3 是 Sigma-1受体选择性拮抗剂,Ki 为 1.14 nM。它抑制 hERG,IC50为 1.54μM。它在神经性疼痛方面有研究的价值。 | |||
T125511 |
Stigmast-7-en-3-ol
|
||
Stigmast-7-en-3-ol 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125511。 | |||
T124943 |
6-Hydroxystigmasta-4,22-dien-3-one
|
||
6-Hydroxystigmasta-4,22-dien-3-one 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124943。 | |||
T71495 |
Monofluoromethylagmatine
|
||
Monofluoromethylagmatine is an arginine decarboxylase inhibitor. | |||
T125112 |
Stigmalactam
|
||
Stigmalactam 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125112。 | |||
T22077 |
Eggmanone
|
||
Eggmanone (EGM1) 是一种有效的、选择性的磷酸二酯酶 4(PDE4)拮抗剂,对 PDE4D3 的 IC50为 72 nM。Eggmanone 对 PDE4D3 的选择性大约是其他 PDE 的 40-50 倍。Eggmanone 通过选择性拮抗 PDE4 发挥 Hh 抑制作用,导致蛋白激酶 A 激活和随后的 Hh 阻断。 | |||
T124527 |
23-O-Acetylshengmanol 3-O-beta-D-xyloside
|
||
23-O-Acetylshengmanol 3-O-beta-D-xyloside 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124527。 | |||
T79149 |
Magmas-IN-1
|
Others | Others |
Magmas-IN-1(compound 9)为针对Magmas的小分子抑制剂(SMMI),后者是线粒体相关粒细胞-巨噬细胞集落刺激因子(GM-CSF)的信号分子,并参与骨髓细胞的GM-CSF诱导基因表达。Magmas-IN-1作用于Magmas,进而调控线粒体功能,并在4 μM浓度下可显著抑制酵母细胞的增殖。 | |||
T78734 |
Sigma-1 receptor antagonist 5
|
Sigma receptor | GPCR/G Protein |
Sigma-1 receptor antagonist 5 (compound 12) 是一种 4-吡啶衍生物,既有镇痛活性也是 sigma 受体 (Ki=4.5 nM (σ1R),10 nM (σ2R)) 及组胺 H3 (hH3R,Ki=7.7 nM,IC50=215 nM) 的拮抗剂。它能够抑制辣椒素引起的痛觉,并展现出对伤害性和神经性疼痛模型的显著疗效。 | |||
T124674 |
3β,5α-Dihydroxystigmastan-6-one
|
||
3β,5α-Dihydroxystigmastan-6-one 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124674。 | |||
T16883 |
Sigma-2 receptor antagonist 1
|
Others | Others |
Sigma-2 receptor antagonist 1 is an antagonist of the sigma-2 (σ-2) receptor. | |||
T124266 |
6α-Hydroxystigmast-4-en-3-one
|
||
6α-Hydroxystigmast-4-en-3-one 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124266。 | |||
T63048 |
Sigma-LIGAND-1 hydrochloride
|
||
Sigma-LIGAND-1 hydrochloride 是一种选择性 sigma 受体配体,能够作用于 DTG (IC50: 16 nM) 和 PPP (IC50: 19 nM) 位点。Sigma-LIGAND-1 hydrochloride 能够作用于多巴胺 D2受体 (Ki: 4000 nM)。 | |||
T33026 |
Lycophlegmarine
|
||
Lycophlegmarine is a bioactive chemical. | |||
T4808L |
Agmatine
NSC 56332,NSC56332,NSC-56332 |
||
Agmatine is decarboxylated arginine. | |||
T74813 |
Sigma-1 receptor antagonist 4
|
Sigma receptor | GPCR/G Protein |
Sigma-1 receptor antagonist 4 (Compound 32) 是一种σ1R拮抗剂,能显著提升吗啡的镇痛效果并逆转吗啡引起的镇痛耐药性,显示出防止吗啡耐药性发展的潜能。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN7150 |
Pygmaniline B
1,3-Bis-(2,4-dimethoxy-phenyl)-urea,1,3-bis(2,4-dimethoxyphenyl)urea,N,N'-bis(2,4-dimethoxyphenyl)urea |
Others | Others |
Pygmaniline B (1,3-bis(2,4-dimethoxyphenyl)urea) 是一种海洋来源的天然产物,存在于Lichina pygmaea。 | |||
T4808 |
Agmatine sulfate
Agmatine sulfate salt,硫酸胍基丁胺 |
Endogenous Metabolite; NO Synthase; Imidazoline Receptor | Immunology/Inflammation; Metabolism; Neuroscience |
Agmatine sulfate (Agmatine sulfate salt) 是咪唑啉受体的内源性激动剂和一氧化氮合酶抑制剂。它靶向神经递质系统,离子通道和一氧化氮合成。 | |||
T5S1679 |
Acetylshengmanol Arabinoside
乙酰升麻醇-3-O-α-L-阿拉伯糖苷,Acetylcimigenol 3-O-alpha-L-arabinopyran |
Others | Others |
Acetylcimigenol 3-O-alpha-L-arabinopyran 是一种升麻提取物。 | |||
T16943 |
Stigmastanol
|
Endogenous Metabolite | Metabolism |
Stigmastanol 是分离自Hypericum riparium 的 6-氨基衍生物。Hypericum riparium 是属于杜仲科的药用植物。 | |||
T2967 |
Stigmasterol
Stigmasterin,beta-Stigmasterol,豆甾醇 |
MMP; Endogenous Metabolite | Metabolism; Proteases/Proteasome |
Stigmasterol (Stigmasterin) 是一种植物性甾醇,具有抑制胆固醇的特性,此外在风湿性疾病的研究中被评价为抗硬化因子。 | |||
TN5064 |
Stigmasta-4,22-dien-3-one
|
Others | Others |
Stigmasta-4,22-dien-3-one has antioxidant activity. | |||
T83259 |
6β-Hydroxystigmasta-4,22-dien-3-one
|
||
6β-Hydroxystigmasta-4,22-dien-3-one为一类固醇化合物,可从Hedychium coronarium中提取。 | |||
T81608 |
O-Methylsterigmatocystin
|
||
O-Methylsterigmatocystin 为黄曲霉菌及寄生曲霉菌的代谢产物。 | |||
TN5069 |
(5α)-Stigmastane-3,6-dione
Stigmastane-3,6-dione,豆甾烷-3,6-二酮 |
||
Stigmastane-3,6-dione has anti-inflammatory activity. 5 alpha-Stigmastane-3,6-dione shows antifeedant activity against bell weevils. | |||
TN5067 |
Stigmastane-3,5,6-triol
|
Antifection | Microbiology/Virology |
Stigmastane-3,5,6-triol and derivatives could be used for preparing antiviral medicine. | |||
T83398 |
23-Acetylshengmanol 3-O-β-D-xylopyranoside
Acetylshengmanol xyloside |
||
23-Acetylshengmanol 3-O-β-D-xylopyranoside(Acetylshengmanol xyloside)为9,19-cyclolanostane型三萜化合物,可自Actaea pachypoda根中分离提取。 | |||
TN2908 |
3,7,16-Trihydroxystigmast-5-ene
|
Others | Others |
3,7,16-Trihydroxystigmast-5-ene 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2908,CAS号为 289056-24-2。 | |||
TN5065 |
Stigmasta-4,25-dien-3-one
|
Others | Others |
Stigmasta-4,25-dien-3-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5065,CAS号为 848669-08-9。 | |||
T81085 |
Stigmasta-3,5-dien-7-one
|
||
Stigmasta-3,5-dien-7-one为源自Harrisonia abyssinica之甾体化合物。 | |||
TN5068 |
Stigmastane-3,6-diol
|
Others | Others |
Stigmastane-3 beta, 6 alpha-diol and stigmastane-3 beta, 6 beta-diol possess marked inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice, the 50% inhibitory dose is 0.5--1.0 mg/ear. | |||
TN5062 | Stigmast-4-ene-3,6-dione | ||
Stigmast-4-ene-3,6-dione has anti-inflammatory and anti-allergic properties. | |||
TN5063 |
Stigmasta-4,22,25-trien-3-one
|
Others | Others |
Stigmasta-4,22,25-trien-3-one is a natural product from Callicarpa giraldiana. | |||
TN1337 |
7Z-Trifostigmanoside I
7-Z-Trifostigmanoside I |
Others | Others |
7-Z-Trifostigmanoside I is a natural product from Polygala hongkongensis Hemsl. | |||
TN5285 |
Stigmast-4-ene-3β,6β-diol
|
||
Stigmast-4-ene-3beta,6beta-diol possesses marked inhibitory activity against 12-O- -tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice. | |||
TN5332 |
Cucumegastigmane I
|
||
Cucumegastigmane I是一种天然产物,属于葫芦科栝楼属,其产品编号为 TN5332,CAS号为 929881-46-9。Cucumegastigmane I可用作对照参考。 | |||
TN5066 | Stigmasta-5,8-dien-3-ol | Others | Others |
Stigmasta-5,8-dien-3-ol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5066,CAS号为 570-72-9。 | |||
T73201 | Stigmane B | ||
Stigmane B 是一个核因子 E2 相关因子 (Nrf2) 激活剂。Stigmane B 抑制细胞凋亡 (apoptosis) 和活性氧 (ROS) 生成,提高抗氧化酶活性。Stigmane B 具有神经保护效果。 | |||
TN2238 |
Stigmasterol glucoside
豆甾醇葡萄糖苷 |
Others | Others |
Stigmasterol glucoside, a constituent of Adenanthera pavonina seed and leaf, may be a plant anticancer agent. | |||
T81086 |
Stigmast-5-ene-3,7-dione
|
||
Stigmast-5-ene-3,7-dione(Compound 10)是一种从Penianthus longifolius的根、叶与细枝中分离得到的化学物质。 | |||
T83339 |
3β-(Acetyloxy)stigmast-5-en-7-one
|
||
3β-(Acetyloxy)stigmast-5-en-7-one 表现出抗补体活性。 | |||
TN3172 |
6beta-Hydroxystigmast-4-en-3-one
|
Others | Others |
6beta-Hydroxystigmast-4-en-3-one 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3172,CAS号为 36450-02-9。 | |||
TN1327 |
7,22,25-Stigmastatrienol
|
Others | Others |
7,22,25-Stigmastatrienol is a natural product | |||
TN5294 |
Stigmasta-4,22-diene-3β,6β-diol
|
||
Stigmasta-4,22-diene-3β,6β-diol 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5294,CAS号为 167958-89-6。 | |||
T16942 |
Sterigmatocystine
|
Others | Others |
Sterigmatocystine is an inhibitor of G1 Phase and DNA synthesis and is used to inhibit p21 activity. Sterigmatocystine is a precursor of aflatoxins and a mycotoxin produced by common mold strains from Aspergillus versicolor. | |||
TN6201 |
(1R,6R,9R)-6,9,11-Trihydroxy-4,7-megastigmadien-3-one 11-O-glucoside
|
||
(1R,6R,9R)-6,9,11-Trihydroxy-4,7-megastigmadien-3-one 11-O-glucoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6201,CAS号为 289914-68-7。 | |||
TN6801 |
Stigmastadienone
|
||
Stigmastadienone is a natural product. | |||
TN4763 |
Phlegmanol C
|
Others | Others |
Phlegmanol C 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4763,CAS号为 1260-05-5。 | |||
TN3254 |
7alpha-Hydroxystigmasterol
|
Others | Others |
7alpha-Hydroxystigmasterol是一种天然产物,属于菊科苍耳属,其产品编号为 TN3254,CAS号为 64998-19-2。7alpha-Hydroxystigmasterol可用作对照参考。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04676 |
MAG Protein, Mouse, Recombinant (His)
myelin associated glycoprotein,siglec-4a,Gma |
Mouse | HEK293 Cells |
MAG Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.3 kDa and the accession number is P20917-2. | |||
TMPY-04662 |
MAG Protein, Mouse, Recombinant (hFc)
myelin associated glycoprotein,Gma,siglec-4a |
Mouse | HEK293 Cells |
MAG Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 81.6 kDa and the accession number is P20917-2. | |||
TMPY-03147 |
MAG Protein, Human, Recombinant (hFc)
S-MAG,SIGLEC4A,myelin associated glycoprotein,SIGLEC-4A,... |
Human | HEK293 Cells |
MAG Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 81.7 kDa and the accession number is P20916-1. | |||
TMPK-00352 |
Siglec-4a/MAG Protein, Human, Recombinant (His & Avi), Biotinylated
S-MAG,MAG,GMA,Siglec-4a,Siglec4a |
Human | HEK293 Cells |
Siglec-4a, also known as Myelin-Associated Glycoprotein (MAG), is a type I transmembrane glycoprotein belonging to the Siglec family, a subgroup of the Ig superfamily. Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (By similarity). | |||
TMPY-02569 |
MAG Protein, Human, Recombinant (His)
SIGLEC4A,myelin associated glycoprotein,SIGLEC-4A,GMA |
Human | HEK293 Cells |
MAG Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56 kDa and the accession number is P20916. | |||
TMPY-02525 |
RGMA Protein, Human, Recombinant (His)
repulsive guidance molecule family member a,RGM |
Human | HEK293 Cells |
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that form... | |||
TMPK-00278 |
RGMA Protein, Human, Recombinant (His & Avi)
RGMA,RGM |
Human | HEK293 Cells |
Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its receptor neogenin regulates axon guidance, neuronal differentiation, and survival during the development of the CNS. RGMa induces T cell activation in experimental autoimmune encephalomyelitis (EAE), which is the animal model of multiple sclerosis (MS). RGM is expressed in pathogenic ... | |||
TMPK-00279 |
RGMA Protein, Human, Recombinant (His & Avi), Biotinylated
RGM,RGMA |
Human | HEK293 Cells |
Repulsive guidance molecule (RGM) is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that has diverse functions in the developing and pathological central nervous system (CNS). The binding of RGM to its receptor neogenin regulates axon guidance, neuronal differentiation, and survival during the development of the CNS. RGMa induces T cell activation in experimental autoimmune encephalomyelitis (EAE), which is the animal model of multiple sclerosis (MS). | |||
TMPH-02996 |
KsdD Protein, Mycobacterium smegmatis, Recombinant (His & Myc)
|
Mycolicibacterium smegmatis | E. coli |
Catalyzes the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids. Is also involved in the formation of 1,4-androstadiene-3,17-dione (ADD) from 4-androstene-3,17-dione (AD) to. KsdD Protein, Mycobacterium smegmatis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 68.9 kDa and the accession number is A0R4S9. | |||
TMPY-01275 |
14-3-3 sigma Protein, Human, Recombinant
stratifin,YWHAS,14-3-3 σ |
Human | E. coli |
14-3-3 sigma Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 28 kDa and the accession number is P31947-1. | |||
TMPH-02997 |
Dps Protein, Mycobacterium smegmatis, Recombinant (His & SUMO)
Neutrophil-activating protein A,NAP A,HP-NAP,Bacterioferriti... |
Mycobacterium smegmatis | E. coli |
Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction. It protects DNA from hydroxyl radical-mediated cleavage. Binds DNA with no apparent sequence specificity without self-aggregation nor promotion of DNA condensation. Is unable to protect DNA from DNase-mediated cleavage. Dps Protein, Mycobacterium sme... | |||
TMPY-02113 |
14-3-3 sigma Protein, Mouse, Recombinant
Mme1,stratifin,Ywhas,Er,14-3-3 σ |
Mouse | E. coli |
14-3-3 sigma Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 27.7 kDa and the accession number is O70456. | |||
TMPH-03148 |
DEFB126 Protein, Pongo pygmaeus, Recombinant (GST)
Defensin, beta 126,DEFB126,Beta-defensin 126 |
Pongo pygmaeus | P. pastoris (Yeast) |
DEFB126 Protein, Pongo pygmaeus, Recombinant (GST) is expressed in yeast with N-GST tag. The predicted molecular weight is 31.9 kDa and the accession number is A4H244. | |||
TMPH-03404 |
Reovirus type 3 (strain Dearing) Outer capsid protein sigma-3 (His)
|
Reo-3 | E. coli |
Stimulates translation by blocking the activation of the dsRNA-dependent protein kinase EIF2AK2/PKR, thereby inhibiting the host interferon response. Sigma3 prevents the activation of EIF2AK2 by competing with the kinase for dsRNA-binding.; The viral outer shell polypeptides, of which sigma-3 is one, impose structural constraints that prevent elongation of nascent transcripts by the RNA-dependent RNA polymerase lambda-3. Reovirus type 3 (strain Dearing) Outer capsid protein sigma-3 (His) is expr... | |||
TMPH-02998 |
Porin MspA Protein, Mycobacterium smegmatis, Recombinant (His)
|
Mycobacterium smegmatis | E. coli |
Porin MspA Protein, Mycobacterium smegmatis, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 25.4 kDa and the accession number is A0QR29. | |||
TMPY-01263 |
14-3-3 sigma Protein, Human, Recombinant (GST)
14-3-3 σ,stratifin,YWHAS |
Human | E. coli |
14-3-3 sigma Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 50.1 kDa and the accession number is P31947-1. | |||
TMPH-00576 |
Agmatinase Protein, E. coli, Recombinant (His & SUMO)
Agmatine ureohydrolase,AUH |
E. coli | E. coli |
Catalyzes the formation of putrescine from agmatine. Agmatinase Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.5 kDa and the accession number is B7LFJ6. |