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Search Results for " gdf-15 "

Targets Recommended: PD-1/PD-L1

1

抑制剂 & 化合物

19

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T80863	Visugromab CTL-002	PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
	Visugromab，作为针对GDF-15的中和IgG4单抗，展现出针对PD-1/PD-L1复发/难治性转移性实体瘤的显著疗效。

化合物

Cat.No: T80863

Synonym: CTL-002

Target: PD-1/PD-L1

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04727	GDF-15 Protein, Human, Recombinant (His) PLAB,PTGFB,NAG-1,MIC1,GDF-15,PDF,MIC-1,gro...	Human	P. pastoris (Yeast)
	GDF-15 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 13.7 kDa and the accession number is Q99988.
TMPY-01073	GDF-15 Protein, Human, Recombinant (hFc) PTGFB,PLAB,MIC-1,MIC1,PDF,NAG-1,growth differentiation facto...	Human	HEK293 Cells
	GDF-15 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.6 kDa and the accession number is Q99988.
TMPK-01243	GDF-15 Protein, Rat, Recombinant (His) GDF-15,PDF,PTGF-beta,MIC-1,MIC1,GDF	Rat	E. coli
	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.68 kDa and the accession number is Q9Z0J6.
TMPK-01246	GDF-15 Protein, Mouse, Recombinant (His) MIC1,Placental TGF-beta,Placental TGF-β,PTGF-beta,PTGFBPTGF-...	Mouse	E. coli
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec...
TMPJ-01414	GDF-15 Protein, Mouse, Recombinant (His & Flag) Growth Differentiation Factor 15, Macrophage inhibi...	Mouse	HEK293 Cells
	Growth Differentiation Factor 15 (GDF-15), also called Macrophage Inhibitory Cytokine 1 (MIC-1), is a divergent member of the TGF-beta superfamily. GDF15 can be secreted by a wide variety of cell types in response to a broad range of stressors. GDF-15 expression is dramatically upregulated during acute brain injury, cancer, cardiovascular disease, and inflammation, suggesting its potential value as a disease biomarker. GDF15 was shown to inhibit proliferation of primitive hematopoietic progenito...
TMPK-01244	GDF-15 Protein, Mouse, Recombinant (hFc) PTGFBPTGF-beta,PTGFB,PLAB,NAG-1,Placental TGF-β,RG-1,GDF...	Mouse	HEK293 Cells
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec...
TMPK-00569	GDF-15 Protein, Canine, Recombinant (His) GDF15,MIC1,MIC-1,PLAB,GDF-15<...	Canine	E. coli
	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Canine, Recombinant (His) is expressed in E. coli expression system with N-His tag. The predicted molecular weight is 13.12 kDa and the accession number is A0A8C0TNP6.
TMPK-00665	GDF-15 Protein, Cynomolgus, Recombinant (His) PTGFBPTGF-beta,PTGFBPTGF-β,MIC-1,NAG-1,MIC1,PTGF-beta,PTGF-β...	Cynomolgus	E. coli
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Cynomolgus...
TMPK-00663	GDF-15 Protein, Cynomolgus, Recombinant (hFc) PTGF-β,GDF-15,NAG-1,PTGF-beta,PDF,PTGFBPTG...	Cynomolgus	HEK293 Cells
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Cynomolgus...
TMPK-00196	GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated NAG-1,Placental TGF-beta,PTGFBPTGF-β,PDF,Placental TGF-β,PTG...	Human	E. coli
	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15. GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 15.19 kDa and the accession nu...
TMPK-01245	GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated RG-1,GDF15,Placental TGF-beta,GDF...	Mouse	HEK293 Cells
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am...
TMPK-00197	GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated Placental TGF-β,GDF15,RG-1,MIC-1,PTGFB,PTG...	Human	HEK293 Cells
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am...
TMPK-00198	GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated MIC-1,PTGFBPTGF-β,GDF15,PTGF-β,GDF	Human	HEK293 Cells
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am...
TMPK-00664	GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated Placental TGF-beta,PTGFBPTGF-β,PLAB,MIC-1,GDF15...	Cynomolgus	HEK293 Cells
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am...
TMPH-01013	BMP-15 Protein, Human, Recombinant (His & Myc) BMP15,GDF-9B,BMP-15,Bone morphoge...	Human	E. coli
	May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth. BMP-15 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.4 kDa and the accession number is O95972.
TMPY-00803	Fibronectin Protein, Human, Recombinant (aa 607-1265, His) GFND,LETS,ED-B,fibronectin 1,CIG,GFND2,FNZ,FINC,FN,MSF	Human	HEK293 Cells
	Fibronectin Protein, Human, Recombinant (aa 607-1265, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.2 kDa and the accession number is P02751-15.
TMPY-05562	Fibronectin Protein, Human, Recombinant (aa 1722-1811, His) fibronectin 1,ED-B,CIG,FNZ,MSF,FN,FINC,GFND,LETS,GFND2	Human	HEK293 Cells
	Fibronectin Protein, Human, Recombinant (aa 1722-1811, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 11.3 kDa and the accession number is P02751-15.
TMPK-01416	HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated MHC,SARS-CoV-2 epitope	Human	HEK293 Cells
	HLA-B15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.
TMPK-01412	HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi) SARS-CoV-2 epitope,MHC	Human	HEK293 Cells
	HLA-B15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.

重组蛋白

GDF-15 Protein, Human, Recombinant (His)

Cat.No: TMPY-04727

Species: Human

Expression System: P. pastoris (Yeast)

GDF-15 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01073

Species: Human

Expression System: HEK293 Cells

GDF-15 Protein, Rat, Recombinant (His)

Cat.No: TMPK-01243

Species: Rat

Expression System: E. coli

GDF-15 Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01246

Species: Mouse

Expression System: E. coli

GDF-15 Protein, Mouse, Recombinant (His & Flag)

Cat.No: TMPJ-01414

Species: Mouse

Expression System: HEK293 Cells

GDF-15 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-01244

Species: Mouse

Expression System: HEK293 Cells

GDF-15 Protein, Canine, Recombinant (His)

Cat.No: TMPK-00569

Species: Canine

Expression System: E. coli

GDF-15 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00665

Species: Cynomolgus

Expression System: E. coli

GDF-15 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPK-00663

Species: Cynomolgus

Expression System: HEK293 Cells

GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00196

Species: Human

Expression System: E. coli

GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated

Cat.No: TMPK-01245

Species: Mouse

Expression System: HEK293 Cells

GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated

Cat.No: TMPK-00197

Species: Human

Expression System: HEK293 Cells

GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated

Cat.No: TMPK-00198

Species: Human

Expression System: HEK293 Cells

GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated

Cat.No: TMPK-00664

Species: Cynomolgus

Expression System: HEK293 Cells

BMP-15 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01013

Species: Human

Expression System: E. coli

Fibronectin Protein, Human, Recombinant (aa 607-1265, His)

Cat.No: TMPY-00803

Species: Human

Expression System: HEK293 Cells

Fibronectin Protein, Human, Recombinant (aa 1722-1811, His)

Cat.No: TMPY-05562

Species: Human

Expression System: HEK293 Cells

HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated

Cat.No: TMPK-01416

Species: Human

Expression System: HEK293 Cells

HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)

Cat.No: TMPK-01412

Species: Human

Expression System: HEK293 Cells

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