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Search Results for " fpps "
Targets Recommended: Others

7

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T73450 TH-Z145

Others Others
TH-Z145 是一种有效的 FPPS 抑制剂,可用于研究骨髓瘤和肺癌。
T73506 TH-Z93

THZ93

Antibacterial Microbiology/Virology
TH-Z93 是一种有效的 FPPS 抑制剂 (IC50: 90 nM),也是一种亲脂性双膦酸盐。
T10586L BPH-1358

NSC50460

Others; Antibacterial Microbiology/Virology; Others
BPH-1358 (NSC-50460) 是一种人 FPPS 和 UPPS 抑制剂,IC50值分别为 1.8 μM 和 110 nM,对金黄色葡萄球菌的 MIC 值大约为 250 ng/mL。
T6373 Alendronate sodium hydrate

G-704650,Alendronate,MK 217,Alendronate sodium trihydrate,阿仑膦酸钠,G-704650 Adronat,Fosamax

Transferase Metabolism
Alendronate sodium hydrate (MK 217) 是 farnesyl diphosphate synthase 抑制剂(IC50:460 nM)。
T22559 Alendronate sodium

Others Others
The compound binds and blocks farnesyl diphosphate synthase in the HMG-CoA pathway (IC50 = 460 nM for recombinant human FPPS). It causes macrophage apoptosis and inhibits prenylation and sterol biosynthesis in purified osteoclasts.
T10586 BPH-1358 free base

NSC50460 free base

Others Others
BPH-1358 (NSC50460) free base is a potent human undecaprenyl diphosphate synthase (UPPS) and farnesyl diphosphate synthase (FPPS) inhibitor (IC50s: 110 nM and 1.8 μM) and is active against S. aureus in vitro (MIC ~250 ng/mL).
T72587 BPH-1358 mesylate

NSC50460 mesylate

BPH-1358 mesylate (NSC50460 mesylate) 是一种有效的人FPPS 和UPPS 抑制剂,IC50值分别为 1.8 μM 和 110 nM,在体外对金黄色葡萄球菌的 MIC 值大约为 250 ng/mL。

化合物

TH-Z145
Cat.No: T73450
Synonym:
Target: Others
TH-Z93
Cat.No: T73506
Synonym: THZ93
Target: Antibacterial
BPH-1358
Cat.No: T10586L
Synonym: NSC50460
Target: Others, Antibacterial
Alendronate sodium hydrate
Cat.No: T6373
Synonym: G-704650,Alendronate,MK 217,Alendronate sodium trihydrate,阿仑膦酸钠,G-704650 Adronat,Fosamax
Target: Transferase
Alendronate sodium
Cat.No: T22559
Synonym:
Target: Others
BPH-1358 free base
Cat.No: T10586
Synonym: NSC50460 free base
Target: Others
BPH-1358 mesylate
Cat.No: T72587
Synonym: NSC50460 mesylate
Target:
Cat. No. Product Name Species Expression System
TMPY-02654 FDPS Protein, Human, Recombinant (His)

FPS,FPPS,Farnesyl pyrophosphate synthase

Human E. coli
FDPS Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 42.4 kDa and the accession number is P14324-2.

重组蛋白

FDPS Protein, Human, Recombinant (His)
Cat.No: TMPY-02654
Species: Human
Expression System: E. coli
TargetMol Loading
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