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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8751 |
AZD8931 diFuMaric acid
4-[[4-[(3-氯-2-氟苯基)氨基]-7-甲氧基-6-喹唑啉基]氧基]-N-甲基-1-哌啶乙酰胺二富马酸盐 |
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
AZD8931 diFuMaric acid 是一种可逆的 ATP 竞争性 EGFR、ErbB2 和 ErbB3 抑制剂(IC50 分别为 4 nM、3 nM 和 4 nM)。 | |||
T5410 |
PD158780
|
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
PD158780是一种EGFR 家族抑制剂,对EGFR、ErbB2、ErbB3和ErbB4的IC50值分别为8 μM、49、52 和 52 nM。 | |||
T6092 |
Sapitinib
沙普替尼,AZD-8931 |
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Sapitinib (AZD-8931) 是可逆的 ATP 竞争型 EGFR 抑制剂,对 EGFR、ErbB2 和 ErbB3的IC50值分别为4、3 和 4 nM。 | |||
T76818 | Lumretuzumab | ||
Lumretuzumab (Anti-Human ERBB3 Recombinant Antibody)为人源化抗HER3 (ERBB3)单克隆抗体,应用于癌症研究。 | |||
T77044 | Istiratumab | ||
Istiratumab (M-6495) 是靶向IGF-1R 和ErbB3的双特异性单克隆抗体。Istiratumab 通过蛋白酶体途径诱导IGF-1R 和 ErbB3 受体降解。Istiratumab 可用于癌症研究。 | |||
T76918 | Barecetamab | ||
Barecetamab (ISU-104) 是一种人源话抗 ErbB3单克隆抗体。Barecetamab 可用于复发/转移性 (R/M) 头颈部鳞状细胞癌 (HNSCC) 的研究。 | |||
T80604 |
Duligotuzumab
RG 7597,MEHD-7945A |
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Duligotuzumab (MEHD-7945A; RG 7597)为一种人源化IgG-κ单克隆抗体,具有针对Her3 (ErbB3) 的特异性靶向能力。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00399 |
HER3/ERBB3 Protein, Human, Recombinant
LCCS2,c-erbB-3,HER3,p180-ErbB... |
Human | HEK293 Cells |
HER3/ERBB3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 69.3 kDa and the accession number is P21860-1. | |||
TMPY-01389 |
HER3/ERBB3 Protein, Human, Recombinant (His)
MDA-BF-1,EEBB3,erbB3-S,p45-sE... |
Human | HEK293 Cells |
HER3/ERBB3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.2 kDa and the accession number is P21860-1. | |||
TMPY-04956 |
HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated
MDA-BF-1,c-erbB-3,HER3,p85-sE... |
Human | HEK293 Cells |
HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.2 kDa and the accession number is P21860-1. | |||
TMPY-02365 |
HER3/ERBB3 Protein, Mouse, Recombinant (His)
Erbb-3r,Erbb3r,erb-b2 re... |
Mouse | HEK293 Cells |
HER3/ERBB3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70 kDa and the accession number is Q61526. | |||
TMPY-03761 |
HER3/ERBB3 Protein, Human, Recombinant (mFc)
c-erbB-3,c-erbB3,HER... |
Human | HEK293 Cells |
HER3/ERBB3 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 95 kDa and the accession number is P21860-1. | |||
TMPY-00795 |
HER3/ERBB3 Protein, Human, Recombinant (hFc)
HER3,c-erbB-3,p180-ErbB<... |
Human | HEK293 Cells |
HER3/ERBB3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.4 kDa and the accession number is P21860-1. | |||
TMPY-05753 |
HER3/ERBB3 Protein, Human, Recombinant (hFc), Biotinylated
HER3,p180-ErbB3,MDA-BF-1,erbB... |
Human | HEK293 Cells |
HER3/ERBB3 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.4 kDa and the accession number is P21860-1. | |||
TMPK-00453 |
HER3/ERBB3 Protein, Human, Recombinant (His & Avi)
p45-sErbB3,MDA-BF-1,ErbB-3 |
Human | HEK293 Cells |
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.6 kDa and the accession number is P21860-1. | |||
TMPY-06631 |
HER3/ERBB3 Protein, Human, Recombinant (His & Avi), Biotinylated
c-erbB3,MDA-BF-1,ErbB-3,... |
Human | HEK293 Cells |
HER3/ERBB3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 71.93 kDa and the accession number is NP_001973.2. | |||
TMPY-00246 |
HER3/ERBB3 Protein, Rhesus, Recombinant
erb-b2 receptor tyrosine kinase 3 |
Rhesus | HEK293 Cells |
HER3/ERBB3 Protein, Rhesus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 69.5 kDa and the accession number is XP_001113953.2. | |||
TMPK-01280 |
HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
p85-sErbB3,HER3,LCCS2,p180-Er... |
Cynomolgus,Rhesus | HEK293 Cells |
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Cynomolgus/Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.54 kDa and the accession number i... | |||
TMPK-00452 |
HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled
LCCS2,HER3c-erbB-3,p180-ErbB<... |
Human | HEK293 Cells |
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). HER3/ERBB3 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 71.6 kDa and the accession numbe... | |||
TMPY-03024 |
HER3/ERBB3 Protein, Rat, Recombinant (His)
erb-b2 receptor tyrosine kinase 3 |
Rat | HEK293 Cells |
HER3/ERBB3 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.9 kDa and the accession number is A6KSF8. | |||
TMPY-04541 |
HER3/ERBB3 Protein, Human, Recombinant (aa 730-1065, His & GST)
c-erbB3,ErbB-3,p45-s... |
Human | Baculovirus Insect Cells |
HER3/ERBB3 Protein, Human, Recombinant (aa 730-1065, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 65 kDa and the accession number is P21860-1. | |||
TMPY-06658 |
HER3/ERBB3 Protein, Mouse, Recombinant (hFc)
Erbb3,C76256,Erbb-3,erb-... |
Mouse | HEK293 Cells |
HER3/ERBB3 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.23 kDa and the accession number is Q61526. | |||
TMPY-02477 |
HER3/ERBB3 Protein, Rhesus, Recombinant (His)
erb-b2 receptor tyrosine kinase 3 |
Rhesus | HEK293 Cells |
HER3/ERBB3 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.1 kDa and the accession number is XP_005571238.1&XP_001113953.2. | |||
TMPY-06659 |
HER3/ERBB3 Protein, Mouse, Recombinant (His & Avi), Biotinylated
C76256,Her3,Erbb-3,Erbb<... |
Mouse | HEK293 Cells |
HER3/ERBB3 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 71.76 kDa and the accession number is Q61526. | |||
TMPJ-00899 |
HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc)
HER3,Proto-oncogene-like protein c-ErbB- |
Human | HEK293 Cells |
HER3/ERBB3 Protein, Human, Recombinant (aa 20-331, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 65 KDa and the accession number is P21860-3. | |||
TMPJ-00413 |
HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated
Proto-oncogene-like protein c-ErbB-3,HER |
Human | HEK293 Cells |
HER3/ERBB3 Protein, Human, Recombinant (aa 20-643, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 90-120 KDa and the accession number is P21860. | |||
TMPY-03023 |
HER3/ERBB3 Protein, Rat, Recombinant (hFc)
erb-b2 receptor tyrosine kinase 3 |
Rat | HEK293 Cells |
HER3/ERBB3 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.5 kDa and the accession number is A6KSF8. | |||
TMPY-02478 |
HER3/ERBB3 Protein, Rhesus, Recombinant (hFc)
erb-b2 receptor tyrosine kinase 3 |
Rhesus | HEK293 Cells |
HER3/ERBB3 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 95.7 kDa and the accession number is XP_001113953.2. | |||
TMPY-06660 |
HER3/ERBB3 Protein, Rhesus, Recombinant (His & Avi), Biotinylated
erb-b2 receptor tyrosine kinase 3 |
Rhesus | HEK293 Cells |
HER3/ERBB3 Protein, Rhesus, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 71.92 kDa and the accession number is XP_001113953.2. | |||
TMPY-02708 |
NRG4 Protein, Human, Recombinant
HRG4,neuregulin 4 |
Human | E. coli |
NRG4 (neuregulin 4) is a member of the neuregulin protein family. The neuregulins consist of four structurally-related proteins that are part of the EGF family of proteins. It has been shown that these proteins have diverse functions in the development of the nervous system and play multiple essential roles in vertebrate embryogenesis including cardiac development, Schwann cell, and oligodendrocyte differentiation, some aspects of neuronal development, as well as the formation of neuromuscular s... | |||
TMPJ-00448 |
NRG1 beta 1 Protein, Human, Recombinant (aa 2-246)
NRG1β,HGL,NDF,NRG1,HRGA,HRG1-beta 1,Pro-neuregulin-1,HRG1-β1... |
Human | E. coli |
Pro-neuregulin-1,Neuregulin-1 beta 1(NRG1) is a single-pass type I membrane protein and belongs to the neuregulin family .It contains 1 EGF-like domain and 1 Ig-like C2-type (immunoglobulin-like) domain. Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. The protein concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. The multiple isoforms perform diverse functions such as inducing growth and ... | |||
TMPY-02844 |
EBP1 Protein, Human, Recombinant (His)
proliferation-associated 2G4,EBP1,p38-2G4,HG4-1 |
Human | E. coli |
EBP1, also known as PA2G4, is an RNA-binding protein that belongs to the peptidase M24 family. It can be detected n several cell lines tested, including primary and transformed cell lines. EBP1 also present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein is a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its int... |