首页工具

登录

搜索结果

Search Results for " e-64 "

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T6037	E-64 Proteinase inhibitor E 64,E 64,E64	Cysteine Protease; Antibacterial; Autophagy	Autophagy; Microbiology/Virology; Proteases/Proteasome
	E-64 (Proteinase inhibitor E 64)是一种不可逆的半胱氨酸蛋白酶抑制剂，抑制papain 的IC50为 9 nM。
T6573	E 64c 阿洛司他丁酸,NSC 694279,EP 475,Loxistatin Acid	SARS-CoV; Cysteine Protease	Microbiology/Virology; Proteases/Proteasome
	E 64c (EP 475) 是一种不可逆且可透过膜的半胱氨酸蛋白酶抑制剂，是 E-64 的衍生物。它也是钙离子激活中性蛋白酶抑制剂和组织蛋白酶 C 弱不可逆抑制剂，可抑制 MERS-CoV。
T11888	LtaS-IN-1	Others; Antibacterial	Microbiology/Virology; Others
	LtaS-IN-1 是多药耐药粪肠球菌中脂磷壁酸合成的有效抑制剂，可改变细胞壁形态。 LtaS-IN-1 对抗肠球菌属 28 菌株，MIC 值从 0.5 μg/mL 到 64 μg/mL 不等。 LtaS-IN-1 抑制菌株 E1630 和 E1590，MIC 值为 0.5 μg/mL。
T82834	Bombinin-BO1
	Bombinin-BO1是一种蟾蜍皮肤分泌物中的抗菌肽，它对大肠杆菌(Escherichia coli)、金黄色葡萄球菌(Staphylococcus aureus)和白色念珠菌(Candida albicans)显示出抗生活性，其最小抑菌浓度(MIC)值分别为64 mg/L, 64 mg/L和128 mg/L。
T38259	Phenelfamycin E
	Phenelfamycin E is an antibiotic originally isolated from Streptomyces. It is active against β-hemolytic Streptoccus, S. pneumoniae, C. difficile, C. perfringens, and P. magnus128 μg/ml). Phenelfamycin E (4-64 mg/kg) increases survival in a mouse model of lethal S. pyogenes infection in a dose-dependent manner. Dietary administration of phenelfamycin E increases body weight in chickens.
T38917	Antibacterial agent 50
	Antibacterial agent 50 (example 47) is a compound that exhibits antibacterial activity. It shows minimum inhibitory concentration (MIC) values of 32, 64, and 128 mcg/mL against three strains of E. coli, namely NCTC 13351, M 50, and 7 MP, respectively (WO2013030733A1).
T78673	Antibacterial agent 135
	Antibacterialagent 135（示例7）是一种针对多种细菌具有抑制作用的有效抗菌剂，包括铜绿假单胞菌、鲍曼不动杆菌、大肠杆菌和肺炎克雷伯菌，其最小抑菌浓度（MIC）大于64 μg/mL。
T39790	LpxC-IN-5
	LpxC-IN-5 is a potent, non-hydroxamate inhibitor of LpxC, which is an enzyme known as UDP-3-O-acyl-N-acetylglucosamine deacetylase. It exhibits an IC50 value of 20 nM. Furthermore, LpxC-IN-5 displays antibacterial activity against various strains including E. coli ATCC25922, P. aeruginosa ATCC27853, K. pneumoniae ATCC13883, and P. aeruginosa 5567. The minimum inhibitory concentration (MIC) values for these strains are 16 μg/mL, 4 μg/mL, 64 μg/mL, and 4 μg/mL, respectively.
T37874	Feglymycin
	Feglymycin is a 13-amino acid peptide originally isolated from Streptomyces that has antibacterial and antiviral activities. It is active against Gram-positive bacteria (MICs = 32-64 μg/ml) and inhibits HIV viral replication in H9 cells (IC50 = ~5 μM). Feglymycin is also active against clinical isolates of HIV-1 from clades A-D, A/E, and G (EC50s = 0.5-6.7 μM). It interacts with gp120 and inhibits HIV-1 NL4.3 binding to human soluble CD4 (EC50 = 4.4 μM) and to CD4+ SupT1 T cells by 74.5% when us...
T36746	Leoidin
	Leoidin is a depsidone originally isolated from L. gangaleoides that has antibacterial and enzyme inhibitory activities.1,2,3 It is active against the bacteria E. faecalis, H. influenzae, M. catarrhalis, S. aureus, and S. pneumoniae (MICs = 8, 32, 1, 128, and 64 μg/ml, respectively).2 Leoidin inhibits phenylalanyl-tRNA synthetase (PheRS) isolated from P. aeruginosa (IC50 = 42 μM). It also inhibits organic anion-transporting polypeptide 1B1 (OATP1B1) and OATP1B3 with Ki values of 0.08 and 1.84 μM...
T83705	BING TFA Blocker of Inter-membrane Stress Responses of Gram-negative Bacteria
	BING是一种来源于日本稻田鱼(O. laptipes)的抗菌肽，由液泡蛋白质分选相关蛋白13D样(Vps13D)衍生而来。对包括耐甲氧西林的金黄色葡萄球菌(MRSA; MICs = 4-64 µg/ml)在内的各种革兰氏阴性和革兰氏阳性细菌都有活性。与氨苄西林、阿莫西林和新霉素共同使用时，对抗铜绿假单胞菌(P. aeruginosa)表现出协同效应，并能抑制大肠杆菌(E. coli)对卡那霉素和氨苄西林的抗药性发展。在体内，BING提高了被鳗弧菌(E. tarda)感染的O. laptipes的生存率。
T38382	8Br-HA
	8Br-HA is an inhibitor of fragile histidine triad diadenosine triphosphatase (FHIT; IC50= 0.12 μM).1It inhibits the growth of HCC827 and H460 lung cancer cells (GI50s = 0.87 and 5.9 μM, respectively). 1.Kawaguchi, M., Sekimoto, E., Ohta, Y., et al.Synthesis of fluorescent probes targeting tumor-suppressor protein FHIT and Identification of apoptosis-inducing FHIT inhibitorsJ. Med. Chem.64(13)9567-9576(2021)
T36110	L-Pyrohomoglutamic Acid
	L-Pyrohomoglutamic acid is an amino acid building block.1,2It has been used in the synthesis of ligands for FK506-binding proteins (FKBPs) and histone deacetylase (HDAC) inhibitors. 1.Pomplun, S., Wang, Y., Kirschner, A., et al.Rational design and asymmetric synthesis of potent and neurotrophic ligands for FK506-binding proteins (FKBPs)Angew. Chem. Int. Ed.54(1)345-348(2015) 2.Taddei, M., Cini, E., Giannotti, L., et al.Lactam based 7-amino suberoylamide hydroxamic acids as potent HDAC inhibitors...
T36649	AN3661
	AN3661, a potent antimalarial lead compound, targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue subunit 3 (PfCPSF3). AN3661 inhibits Plasmodium falciparum laboratory-adapted strains, Ugandan field isolates, and murine P. berghei and P. falciparum infections[1]. AN3661 is active at nanomolar (IC50=20-56 nM) concentrations against P. falciparum laboratory strains known to be sensitive (3D7) or resistant (W2, Dd2, K1, HB3, FCR3 and TM90C2B), and AN3661 is simi...
T35683	2-deoxy-D-Glucose-13C6 2-deoxy-D-Glucose-13C6
	2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits hexokinase, the enzyme that converts glucose to glucose-6-phosphate, as well as phosphoglucose isomerase, the enzyme that converts glucose-6-phosphate to fructose-6-phosphate.32-deoxy-D-Glucose (16 mM) induces apoptosis in SK-BR-3 cells, as well as inhibits the growth of 143B oste...
T35881	Resolvin E2
	Resolvin E2 (RvE2) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.1It is produced from eicosapentaenoic acidviaan 18-HEPE intermediate, which is formed by aspirin-acetylated COX-2-mediated oxidation of EPA, by 5-lipoxygenase (5-LO) in human polymorphonuclear (PMN) neutrophils.2,3RvE2 (20 ng/animal) inhibits increases in inflammatory exudate neutrophil infiltration in a mouse model of peritonitis induced by zymosan A .3Hepatic RvE2 levels are increased in m...

化合物

Cat.No: T6037

Synonym: Proteinase inhibitor E 64,E 64,E64

Target: Cysteine Protease, Antibacterial, Autophagy

Cat.No: T6573

Synonym: 阿洛司他丁酸,NSC 694279,EP 475,Loxistatin Acid

Target: SARS-CoV, Cysteine Protease

Cat.No: T11888

Target: Others, Antibacterial

Cat.No: T82834

Phenelfamycin E

Cat.No: T38259

Antibacterial agent 50

Cat.No: T38917

Antibacterial agent 135

Cat.No: T78673

Cat.No: T39790

Cat.No: T37874

Cat.No: T36746

Cat.No: T83705

Synonym: Blocker of Inter-membrane Stress Responses of Gram-negative Bacteria

Cat.No: T38382

L-Pyrohomoglutamic Acid

Cat.No: T36110

Cat.No: T36649

2-deoxy-D-Glucose-13C6

Cat.No: T35683

Synonym: 2-deoxy-D-Glucose-13C6

Cat.No: T35881

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼