Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T77614 |
DpC
|
Others | Others |
DPC 是一种抗肿瘤化合物,对癌细胞增殖有抑制作用,IC50为 0.007-0.096 μM。DPC 可参与多种抗癌疗法,可用于研究癌症。 | |||
TP1906L1 |
DPC AJ1951 acetate
|
Thyroid hormone receptor(THR) | Endocrinology/Hormones |
DPC-AJ1951 acetate 是一种 14 个氨基酸的肽,可作为甲状旁腺激素 (PTH)/PTH 相关肽受体 (PPR) 的有效激动剂。在骨吸收的体外和体内测定中表征了它的活性。 | |||
T37409 |
DPC-AJ1951 (trifluoroacetate salt)
DPC-AJ1951 (trifluoroacetate salt) |
||
DPC-AJ1951 is a peptide agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR; EC50 = 0.15 nM in HEK293 cells expressing human PPR). It induces cAMP production in SAOS-2 and UMR106 cells that endogenously express human and rat PPR, respectively (EC50s = 2.2 and 1.1 nM, respectively). DPC-AJ1915 stimulates osteoclast-mediated bone resorption in fetal rat long-bone explant cultures and increases collagen synthesis and cell proliferation in neonatal mouse parietal bone explants... | |||
T27201 |
DPC-082
DPC 082 |
||
DPC-082 is a reverse transcriptase inhibitor. DPC-082 exhibits low-nanomolar potency toward wild-type virus, L100I and K103N single-mutation variants, and multiplies amino acid-substituted HIV type 1 mutants. | |||
T27202 |
DPC-423
DPC-423 Free |
||
DPC-423 is a factor Xa inhibitor potentially for the treatment of thrombosis. | |||
TP1906 |
DPC-AJ1951
DPC AJ1951 |
||
Potent 14 amino acid peptide agonist of the parathyroid hormone (PTH) receptor (EC50 = 26 nM). | |||
T27204 |
DPC-963
DMP 963,DMP963,DMP-963,DPC 963,DPC963 |
||
DPC-963 is a RNA-directed DNA polymerase inhibitor. | |||
T15163 |
DPC-681
DPH-153893 |
Others | Others |
DPC-681 is a potent and selective HIV protease inhibitor (IC90s: 4 to 40 nM for wild-type HIV-1). | |||
T27203 |
DPC-961
DMP 961,DMP-961,DMP961 |
||
DPC-961, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection. | |||
T27154 |
Dexelvucitabine
D-D-4FC,DPC-817,RVT,beta-D-D-4FC,DFC |
Reverse Transcriptase | Microbiology/Virology |
Dexelvucitabine (RVT) 是一种胞苷类似物,一种口服有活性的核苷逆转录酶抑制剂。它是一种 2'-脱氧胞苷抗逆转录病毒剂。它是一种有效的抗 HIV-1病毒剂,这些病毒聚合酶中含有胸苷类似物和/或 M184V 突变。 | |||
T19729 |
Dodecylphosphocholine
FOS-维生素B-12,DPC,n C12PC,Foscholine-12,DDPPC,nC12PC,n-C12PC |
Others | Others |
Dodecylphosphocholine (DPC) 是一种去污剂,普遍用于膜蛋白核磁共振的研究。 | |||
T26851 |
BMS-561390
DPC083,DPC 083,DPC-083 |
||
BMS-561390, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection. | |||
T12694 |
Razaxaban hydrochloride
BMS 561389 hydrochloride,DPC 906 hydrochloride |
Others | Others |
Razaxaban hydrochloride is a highly potent, selective and orally active inhibitor of factor Xa(Ki of 0.19 nM),has strongly antithrombotic activity. | |||
T30531 |
BMS-561392
DPC333,DPC 333,DPC-333,BMS561392,BMS 561392 |
TNF | Apoptosis |
BMS-561392 (DPC333)是一种肿瘤坏死因子-α(TNF-α)转化酶抑制剂。 | |||
T75942 |
DPC-AJ1951 TFA
|
||
DPC-AJ1951 TFA,是一种含有14个氨基酸的肽类化合物,有效充当甲状旁腺激素(PTH)/PTH相关肽受体(PPR)激动剂,在体外及体内骨吸收实验中展现活性。 | |||
T27289 |
Etacstil
GW 5638,GW-5638,GW5638,DPC974,DPC 974,DPC-974 |
||
GW5638 is a estrogen receptor ligand. GW5638 is a prodrug of its active metabolite GW7604. GW5638 appears to act as an antagonist in these in vitro systems, although in a manner distinct from other known ER modulators. GW5638 is also classified as a pseud | |||
T22744 |
DPCPX
PD 116948,1,3-二丙基-8-环戊基黄嘌呤 |
Adenosine Receptor | GPCR/G Protein; Neuroscience |
DPCPX (PD 116948) 是一种黄嘌呤衍生物,是一种选择性腺苷 A1 受体的拮抗剂,Ki 值为 0.46 nM。 | |||
T21653 |
1,4-DPCA
|
HIF/HIF Prolyl-Hydroxylase | Chromatin/Epigenetic; Metabolism |
1,4-DPCA 是一种脯氨酰羟化酶抑制剂,对人源包皮成纤维细胞中胶原羟基化的 IC50 为 2.4 μM,对因子抑制 HIF (FIH) 的 IC50 为 60 μM。 | |||
T36796 |
1,4-DPCA ethyl ester
|
||
1,4-DPCA ethyl ester, the ethyl ester derivative of 1,4-DPCA, acts as an inhibitor of the enzyme factor inhibiting HIF (FIH)[1]. | |||
T36745 |
cDPCP
|
||
cDPCP is a platinum-containing DNA-crosslinking agent.1Unlike cisplatin or oxaliplatin , cDPCP forms monofunctional DNA adducts. It is transported into cells by organic cation transporter 1 (OCT1) and OCT2, inhibiting proliferation of MDCK cells expressing the human transporters with IC50values of 8.1 and 1.5 μM, respectively. cDPCP inhibits RNA polymerase II-mediated transcription in a reporter assay using HeLa cells. It increases survival in murine S180 sarcoma and P388 leukemia models when ad... |