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Cat. No. Product Name Target Signaling Pathways
T15109 DGAT1-IN-1

Transferase Metabolism
DGAT1-IN-1DGAT1的高效抑制剂,在 Hep3B 细胞过表达 DGAT1裂解物中,测得IC50低于10nM。
T4681 T863

DGAT-3,DGAT-1 inhibitor

Acyltransferase; Transferase Metabolism
T863 (DGAT-3) 是口服有效的二酰基甘油酰基转移酶1 选择性抑制剂。T863结合DGAT1的酰基辅酶A 结合位点,抑制三酰甘油在细胞内的合成。
T11827 Pradigastat

ANJ908,LCQ908-NXA,LCQ908A,LCQ-908

Transferase Metabolism
Pradigastat (LCQ-908) 是一种具有口服活性、有效性和选择性的二酰基甘油酰基转移酶 1 (DGAT1) 抑制剂,可用于治疗便秘,可用于研究肥胖和糖尿病。
T62220 DGAT1-IN-3

DGAT1-IN-3 是一种选择性的、有效的,口服具有活力的 DGAT-1 抑制剂,能够抑制人类 DGAT-1 (IC50: 38 nM) 和大鼠 DGAT-1 (IC50: 120 nM)。DGAT1-IN-3 能够用于肥胖、血脂异常和代谢综合征的研究。
T14382 AZD7687

Others Others
AZD7687 is a potent and selective DGAT1 inhibitor with an IC50 value of 80 nM (hDGAT1). IC50 value: 80 nM [1] Target: DGAT1 in vitro: Plasma AZD7687 exposure was measured repeatedly. AZD7687 markedly reduced postprandial TAG excursion with a steep concent
T71886 ALN29882

ALN29882 is a glycerolipid, that is located at the plasma membrane. It is made up of two fatty acid chains that are covalently attached to a single glycerol molecule with the help of an ester linkage. 18:1 DG has been used as a diacyl-glycerol source in diacylglycerol O-acyltransferase 1 (DGAT1) assay. It has also been used as substrate to assess compounds as potential inhibitors of DGAT-1 in DGAT-1 enzyme assay. It is suitable to use in lipid-protein overlay screen assay with the recombinant p...

化合物

DGAT1-IN-1
Cat.No: T15109
Synonym:
Target: Transferase
T863
Cat.No: T4681
Synonym: DGAT-3,DGAT-1 inhibitor
Target: Acyltransferase, Transferase
Pradigastat
Cat.No: T11827
Synonym: ANJ908,LCQ908-NXA,LCQ908A,LCQ-908
Target: Transferase
DGAT1-IN-3
Cat.No: T62220
Synonym:
Target:
AZD7687
Cat.No: T14382
Synonym:
Target: Others
ALN29882
Cat.No: T71886
Synonym:
Target:
TargetMol Loading
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