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Search Results for " d-isomer "

18

抑制剂 & 化合物

7

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T68002L	(R)-Naroparcil 4-[4-[(5-Thio-α-D-xylopyranosyl)thio]benzoyl]benzonitrile(Isomer-120819-70-7)	Others	Others
	(R)-Naroparcil 是 Naroparcil 的异构体。 Naroparcil 是一种4-甲基伞形酮基 β-D-木糖苷类似物，与血管平滑肌细胞增殖有关，在 Wessler 淤滞模型中抑制血栓的形成。
T19107	24, 25-Dihydroxy VD2 24,25-Dihydroxy vitamin D2	Vitamin	Metabolism
	24, 25-Dihydroxy VD2 (24,25-Dihydroxy vitamin D2) 是维生素 D2 的代谢产物，是维生素 D在体内存在25 羟维生素 D 的异构体。
TP1166	ZINC77292789 Fmoc-Thr[GalNAc(Ac)3-α-D]-OH,Fmoc-Thr(Ac₃AcNH-α-Gal)-OH	Others	Others
	ZINC77292789 (Fmoc-Thr[GalNAc(Ac)3-α-D]-OH) 是制备基于三聚体 MUC1 免疫显性基序抗原的候选抗癌疫苗的起始材料，可制备含有 βGalNAc-Thr 作为 Tn 抗原异构体的合成 MUC1 糖肽，可诱导针对肿瘤细胞的抗体产生。
T19611	(2R)-Octyl-α-hydroxyglutarate (2R)-Octyl-2-HG	Pim	Chromatin/Epigenetic; JAK/STAT signaling
	(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a D-isomer 2-Hydroxyglutarate modified form.
T24408	L-Glucose-1-14C L-(1-14C)Glucose
	L-Glucose-1-14C is the L-isomer of glucose. It also is the enantiomer of the more common D-glucose.
T71323	Npc 12626
	Npc 12626 is a N-methyl-D-aspartate receptor antagonist; NPC 17742, the (2R,4R,5S)-isomer, is the most potent isomer in the mixture NPC 12626.
T13197	trans-Doxercalciferol	Others	Others
	trans-Doxercalciferol is an isomer of Doxercalciferol. Doxercalciferol is an activator of the Vitamin D receptor and prevents renal disease.
T37899	UDP-β-D-Glucose (sodium salt)
	UDP-β-D-Glucose is the stereoisomer of UDP-α-D-glucose (sodium salt) . The activities of the UDP-β-D-glucose isomer are not known.
T36069	L-myo-Inositol-1,4,5-triphosphate (sodium salt)
	Ins(1,4,5)P3 is an isomer of the biologically important D-myo-inositol-1,4,5-triphosphate. Unlike its isomer, Ins(1,4,5)P3 does not evoke a rise in intracellular calcium when added to cells. It is not known if Ins(1,4,5)P3 can act as a competitive inhibitor of biologically-active inositol phosphates.
T17951	Fmoc-Gly-Gly-D-Phe-OtBu	Others	Others
	Fmoc-Gly-Gly-D-Phe-OtBu, an ADC cleavable linker, is utilized in the synthesis of antibody-drug conjugates. It is the R-isomer of Fmoc-Gly-Gly-Phe-OtBu [1].
T38489	D,L-erythro-PDMP
	D,L-erythro-PDMP, an erythro isomer of PDMP, exhibits growth inhibition on cultured rabbit skin fibroblasts. Additionally, this compound serves as an effective inhibitor of UDP-glucose: ceramide glucosyltransferase.
T37245	Palmitoyl-D-carnitine (chloride)
	Palmitoyl-D-carnitine is a long-chain acylcarnitine, an isomer of palmitoyl-L-carnitine , and the D enantiomer of palmitoyl-DL-carnitine . It inhibits carnitine palmitoyltransferase with a Ki value of 2.1 mM for 14C-palmitoylcarnitine synthesis by erythrocyte membranes.
T19264	D-Methionine sulfoxide hydrochloride D-Methionine sulfoxide hydrochloride (21056-56-4 free base)	Others	Others
	D-methionine sulfoxide hydrochloride is the D-isomer of methionine sulfoxide hydrochloride. Methionine sulfoxide is the oxidation product of methionine. Methionine is a restrictive amino acid in milk or legume proteins and is easily oxidized during storag
T72129	D,L-erythro-PDMP hydrochloride
	D,L-erythro-PDMP hydrochloride 是 PDMP 的赤型异构体。D,L-erythro-PDMP 诱导体外兔皮肤成纤维细胞的生长抑制。PDMP 是一种 UDP 葡萄糖神经酰胺葡萄糖基转移酶抑制剂。
T78508	Delmitide acetate RDP-58 acetate	IFNAR	Immunology/Inflammation
	Delmitide acetate (RDP58) 是一种 d-异构体十肽，具有抗炎活性和口服活性。该化合物能够抑制 TNF-α、IFN-γ 以及白细胞介素 (IL)-12 的生成，同时提高血红素加氧酶 1 的活性，可用于针对溃疡性结肠炎的研究。
T35436	(-)-L-threo-PDMP (hydrochloride)
	(-)-L-threo-PDMP is an enhancer of ganglioside biosynthesis. The (-)-L-threo-PDMP (1S,2S) isomer is the active stimulatory component of DL-threo-PDMP in contrast to (+)-D-threo-PDMP , which is an inhibitor of glucosylceramide synthetase. (-)-L-threo-PDMP upregulates GM3, GD3, and GQ1b synthase levels, which are glycosyltransferases involved in ganglioside biosynthesis, and increases ganglioside levels in cells. It increases neurite outgrowth and synapse formation in vitro and improves retention ...
T35781	Sphinganine (d20:0) Sphinganine (d20:0)
	Sphinganine (d20:0) is a natural isomer of dihydro-D-erythro-sphinganine (sphinganine (d18:0); that is a precursor of ceramide and sphingosine as well as a substrate for sphingosine kinases, which generate sphingosine-1-phosphate (d18:1) . In S. cerevisiae, the amount of sphinganine (d20:0) increases 10.8-fold in response to heat stress, indicating it is involved in heat stress adaptation. Sphinganine levels increase significantly in response to certain mycotoxins, including fumonisins as well ...
T80265	C5a Receptor agonist, mouse, human	Complement System	Immunology/Inflammation
	C5a Receptor agonist, mouse, human 是一种源自血浆蛋白C5a C末端的生物活性肽，充当C5a受体激动剂。此化合物在调控细胞炎症反应中起关键作用，包括促进趋化性、白细胞脱颗粒、增加血管通透性以及刺激细胞因子的产生。化合物的结构中，第5位环己基丙氨酸对激动剂功能至关重要，同时末端的Arg采用d-异构体形式。

化合物

Cat.No: T68002L

Synonym: 4-[4-[(5-Thio-α-D-xylopyranosyl)thio]benzoyl]benzonitrile(Isomer-120819-70-7)

Target: Others

24, 25-Dihydroxy VD2

Cat.No: T19107

Synonym: 24,25-Dihydroxy vitamin D2

Target: Vitamin

Cat.No: TP1166

Synonym: Fmoc-Thr[GalNAc(Ac)3-α-D]-OH,Fmoc-Thr(Ac₃AcNH-α-Gal)-OH

Target: Others

(2R)-Octyl-α-hydroxyglutarate

Cat.No: T19611

Synonym: (2R)-Octyl-2-HG

Target: Pim

L-Glucose-1-14C

Cat.No: T24408

Synonym: L-(1-14C)Glucose

Cat.No: T71323

trans-Doxercalciferol

Cat.No: T13197

Target: Others

UDP-β-D-Glucose (sodium salt)

Cat.No: T37899

L-myo-Inositol-1,4,5-triphosphate (sodium salt)

Cat.No: T36069

Fmoc-Gly-Gly-D-Phe-OtBu

Cat.No: T17951

Target: Others

D,L-erythro-PDMP

Cat.No: T38489

Palmitoyl-D-carnitine (chloride)

Cat.No: T37245

D-Methionine sulfoxide hydrochloride

Cat.No: T19264

Synonym: D-Methionine sulfoxide hydrochloride (21056-56-4 free base)

Target: Others

D,L-erythro-PDMP hydrochloride

Cat.No: T72129

Delmitide acetate

Cat.No: T78508

Synonym: RDP-58 acetate

Target: IFNAR

(-)-L-threo-PDMP (hydrochloride)

Cat.No: T35436

Sphinganine (d20:0)

Cat.No: T35781

Synonym: Sphinganine (d20:0)

C5a Receptor agonist, mouse, human

Cat.No: T80265

Target: Complement System

Cat. No.	Product Name	Target	Signaling Pathways
T10933	D-Cysteine	Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology
	D-Cysteine 是一种大肠杆菌生长的有力抑制剂，是半胱氨酸的 D 型异构体。它由 D-氨基酸氧化酶介导产生 H2S，是一种对抗小脑共济失调的神经保护剂。 D-半胱氨酸可以抑制由变形链球菌和链球菌血红蛋白形成的两种生物膜的生长和致龋性。
T6608	NMDA N-甲基-D-天冬氨酸,N-Methyl-D-aspartic acid	Endogenous Metabolite; NMDAR; iGluR	Membrane transporter/Ion channel; Metabolism; Neuroscience
	NMDA (N-Methyl-D-aspartic acid) 是一种氨基酸，作为 D-异构体，是谷氨酸受体的 NMDA 受体亚型的定义激动剂。
T0592	D-Mannopyranose Mannose,D-甘露糖	Others	Others
	D-Mannopyranose (Mannose) 是一种己糖或可发酵单糖，是甘露糖、水曲柳和相关植物的葡萄糖异构体。
TN1545	D-Tyrosine	Tyrosinase	Proteases/Proteasome
	D-Tyrosine，是酪氨酸的D异构体，通过抑制酪氨酸酶活性，作为黑色素合成的负向调节剂。此外，D-Tyrosine还能抑制生物膜的形成，并诱导生物膜的自我分散，同时不影响细菌的生长。
T5220	D-(-)-Lactic acid sodium Sodium D-lactate,D-乳酸钠	Others; Endogenous Metabolite	Metabolism; Others
	D-(-)-Lactic acid sodium (Sodium D-lactate) 是一种有机酸。它是一种手性分子，由 L-乳酸和 D-乳酸两种光学异构体组成，其中 L-异构体在生物体中最常见。D-(-)-Lactic acid sodium 也是一种微生物代谢产物。
T5302	(R)-pyrrolidine-2-carboxylic acid D-脯氨酸,D-Proline	Others; Endogenous Metabolite	Metabolism; Others
	(R)-pyrrolidine-2-carboxylic acid (D-Proline) 是天然氨基酸 L -脯氨酸的异构体。D -氨基酸在人类血浆和唾液中含量相对较高。这些氨基酸可能是细菌来源，但也有证据表明它们是通过氨基酸消旋酶活性内源性产生的。
T4723	D-Tagatose 塔格糖,D-(-)-Tagatose,D-塔格糖,d-tagatos	Others; Endogenous Metabolite	Metabolism; Others
	D-Tagatose (D-(-)-Tagatose) 是自然界中发现的一种罕见的单糖，具有益生元特性。它是研究II 型糖尿病的潜在抗糖尿病药物，也是帮助提升结肠有益细菌、预防结肠癌和抑制胆固醇的益生元。它是蔗糖的替代品，也是口香糖、果汁和饮料等食品中的低热量甜味剂。

天然产物

Cat.No: T10933

Target: Endogenous Metabolite, Antibacterial

Cat.No: T6608

Synonym: N-甲基-D-天冬氨酸,N-Methyl-D-aspartic acid

Target: Endogenous Metabolite, NMDAR, iGluR

D-Mannopyranose

Cat.No: T0592

Synonym: Mannose,D-甘露糖

Target: Others

Cat.No: TN1545

Target: Tyrosinase

D-(-)-Lactic acid sodium

Cat.No: T5220

Synonym: Sodium D-lactate,D-乳酸钠

Target: Others, Endogenous Metabolite

(R)-pyrrolidine-2-carboxylic acid

Cat.No: T5302

Synonym: D-脯氨酸,D-Proline

Target: Others, Endogenous Metabolite

Cat.No: T4723

Synonym: 塔格糖,D-(-)-Tagatose,D-塔格糖,d-tagatos

Target: Others, Endogenous Metabolite

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