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搜索结果

Search Results for " claudin "
Targets Recommended: Others

5

抑制剂 & 化合物

26

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T73593 PDS-0330

Others Others
PDS-0330是一种 claudin-1小分子抑制剂抑制。PDS-0330抑制 claudin-1依赖性 CRC 进展，以微摩尔亲和力直接和特异性地与claudin-1结合。PDS-0330通过抑制与转移性癌基因Src 的关联，表现出具有良好药代动力学特性的抗肿瘤和化学增敏活性。PDS-0330干扰claudin-1 / Src 关联以抑制CRC 进展和转移。
T9901A-005 Zolbetuximab

IMAB362

 Others Others
Zolbetuximab(IMAB362) 是一种特异性靶向 Claudin-18.2 的单克隆抗体。Zolbetuximab 具有潜在的抗肿瘤活性，通过免疫效应机制介导对 Claudin-18.2 阳性细胞的杀伤作用。Zolbetuximab 可用于研究胃肠道腺癌和胰腺肿瘤。
T35337L Teduglutide acetate

Glucagon Receptor GPCR/G Protein
Teduglutide acetate 是一种 GLP-2 类似物，可使小肠黏膜肥大。它通过改变 claudin-10 的分布部分恢复小肠上皮功能，促进钠再循环以进行钠耦合葡萄糖转运和水吸收。
T81594 Osemitamab

TST001
Osemitamab是一种针对人类claudin-18.2的IgG1单克隆抗体。它由来自人鼠嵌合体TST001的γ-1链与κ链通过二硫键连接而成的二聚体(ACI)构成。该化合物与Capecitabine和Oxaliplatin联合应用，适用于胃(G)及胃食管结合部(GEJ)癌症的研究。
T78296 IMAB027

ASP1650
IMAB027 (ASP1650)是针对CLDN6 (Claudin 6)的特异性单克隆抗体，CLDN6作为一种紧密连接蛋白，其在多种人类癌症中异常高表达，尤其显著于卵巢癌。IMAB027展现出抗肿瘤特性，并能诱导表达CLDN6的卵巢癌和睾丸癌细胞走向凋亡。

化合物

PDS-0330
Cat.No: T73593
Synonym:
Target: Others
Zolbetuximab
Cat.No: T9901A-005
Synonym: IMAB362
Target: Others
Teduglutide acetate
Cat.No: T35337L
Synonym:
Target: Glucagon Receptor
Osemitamab
Cat.No: T81594
Synonym: TST001
Target:
IMAB027
Cat.No: T78296
Synonym: ASP1650
Target:
Species：
Human (22)
Cynomolgus (2)
Mouse (2)
Expression System：
HEK293 Cells (21)
E. coli (5)
Tag：
Tag Free (6)
C-10xHis (This tag can be tested only under denaturing conditions) (2)
N-6xHis (This tag can be tested only under denaturing conditions) (2)
N-8xHis (2)
C-His-Avi (1)
GFP, His (1)
His, Avi (1)
His, Flag (1)
N-10xHis (1)
N-6xHis, C-Avi (1)
Cat. No. Product Name Species Expression System
TMPY-06586 Claudin-6 Protein, Human, Recombinant

claudin 6

 Human HEK293 Cells
Claudin-6 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23.30 kDa and the accession number is NP_067018.2.
TMPY-06965 Claudin-6 Protein, Human, Recombinant (GFP & His)

claudin 6

 Human HEK293 Cells
Claudin-6 Protein, Human, Recombinant (GFP & His) is expressed in HEK293 mammalian cells with GFP and His tag. The predicted molecular weight is 23.3 kDa and the accession number is P56747-1.
TMPY-06805 Claudin-6 Protein, Human, Recombinant (His & FLAG)

claudin 6

 Human HEK293 Cells
Claudin-6 Protein, Human, Recombinant (His & FLAG) is expressed in HEK293 mammalian cells with His and Flag tag. The predicted molecular weight is 21.87 kDa and the accession number is P56747.
TMPY-06766 Claudin-6 Protein, Human, Recombinant, Fluorescent,VLP

claudin 6

 Human HEK293 Cells
Claudin-6 Protein, Human, Recombinant, Fluorescent,VLP is expressed in HEK293 mammalian cells. The predicted molecular weight is 50.31 kDa and the accession number is P56747.
TMPJ-01029 Claudin-18.2 Protein, Human, Recombinant (His)

Claudin-18,CLDN18

 Human E. coli
Claudin-18.2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-8xHis tag. The predicted molecular weight is 18 KDa and the accession number is P56856-2.
TMPJ-01027 Claudin-18.2 Protein, Human, Recombinant (His & Avi), Biotinylated

Claudin-18,CLDN18

 Human E. coli
Claudin-18.2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-6xHis and C-Avi tag. The predicted molecular weight is 13 KDa and the accession number is P56856-2.
TMPY-06851 Claudin-6 Protein, Human, Recombinant (His & Avi), Biotinylated

claudin 6

 Human HEK293 Cells
Claudin-6 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 22.7 kDa and the accession number is P56747.
TMPJ-01028 Claudin-18.2 Protein, Human, Recombinant (Twin strep & Flag)

Claudin 18.2,CLDN18,Claudin-18,CLDN18.2,

Human HEK293 Cells
Claudin-18 (CLDN18) is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. CLDN18 has two isoform A1 and isoform A2. Human CLDN18.2 is highly expressed in a signifcant proportion of gastric and pancreat...
TMPY-03175 Claudin-11 Protein, Human, Recombinant (mFc)

claudin 11,OTM,OSP

 Human HEK293 Cells
Claudin-11, also known as CLDN11, belongs to the group of claudins. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands function as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions.Claudin-11 is a tight junction associated protein and is a major component of central ...
TMPY-06942 Claudin-18 Protein, Human, Recombinant (His & Strep)

SFTA5,claudin 18,SFTPJ

 Human HEK293 Cells
Claudin-18 Protein, Human, Recombinant (His & Strep) is expressed in HEK293 mammalian cells with His and Strep tag. The predicted molecular weight is 32.34 kDa and the accession number is P56856-2.
TMPY-06596 Claudin-18.2 Protein-VLP, Human, Recombinant

claudin 18,SFTPJ,SFTA5

 Human HEK293 Cells
Claudin-18.2 Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 27.72 kDa and the accession number is NP_001002026.1.
TMPY-06822 Claudin-18 Protein, Human, Recombinant (CLDN18.2), Fluorescent

SFTPJ,claudin 18,SFTA5

 Human HEK293 Cells
Claudin-18 Protein, Human, Recombinant (CLDN18.2), Fluorescent is expressed in HEK293 mammalian cells. The predicted molecular weight is 54.74 kDa and the accession number is P56856-2.
TMPK-00667 Claudin-6 Protein-VLP, Cynomolgus, Recombinant

Claudin6,Skullin,Claudin,Claudin-...

 Cynomolgus HEK293 Cells
Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively. Claudin-6 Protein-VLP, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.60 kDa and the accession number is G7Q0B0.
TMPJ-01026 Claudin-18.1 Protein, Human, Recombinant (His)

CLDN18,Claudin-18

 Human E. coli
Claudin-18.1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-8xHis tag. The predicted molecular weight is 18 KDa and the accession number is P56856.
TMPK-00904 Claudin-6 Protein-VLP, Human, Recombinant

Skullin 2,CLDN6,Claudin-6,Skullin,Claudin6

 Human HEK293 Cells
Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively. Claudin-6 Protein-VLP, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.5 kDa and the accession number is P56747.
TMPY-06828 Claudin-18 Protein, Human, Recombinant (CLDN18.1)

claudin 18,SFTA5,SFTPJ

 Human HEK293 Cells
Claudin-18 Protein, Human, Recombinant (CLDN18.1) is expressed in HEK293 mammalian cells. The predicted molecular weight is 27.86 kDa and the accession number is P56856-1.
TMPK-01249 Claudin-6 Protein-VLP, Mouse, Recombinant

Claudin6,Claudin-6,CLDN6,Skullin,Skullin 2

 Mouse HEK293 Cells
Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively. Claudin-6 Protein-VLP, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.60 kDa and the accession number is Q9Z262.
TMPH-02423 Claudin-18 Protein-VLP, Cynomolgus, Recombinant (His)

Claudin 18,CLDN18

 Cynomolgus HEK293 Cells
Claudin-18 Protein-VLP, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis (This tag can be tested only under denaturing conditions) tag. The predicted molecular weight is 28.7 kDa and the accession number is A0A2K5VV62.
TMPH-02586 Claudin-18 Protein-VLP, Mouse, Recombinant (His)

Claudin 18,CLDN18

 Mouse HEK293 Cells
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-18 Protein-VLP, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis (This tag can be tested only under denaturing conditions) tag. The predicted molecular weight is 29.1 kDa and the accession number is P56857.
TMPH-01104 Claudin-9 Protein-VLP, Human, Recombinant (His)

CLDN9,Claudin-9

 Human HEK293 Cells
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.; (Microbial infection) Acts as a receptor for hepatitis C virus (HCV) entry into hepatic cells. Claudin-9 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 24.2 kDa and the accession number is O95484.
TMPK-00710 Claudin-4 Protein-VLP, Human, Recombinant

Claudin4,CLDN4,Claudin-4,CPETR1,CPE-R,WBSC...

 Human HEK293 Cells
Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs in...
TMPH-01103 Claudin-3 Protein-VLP, Human, Recombinant (His)

Clostridium perfringens enterotoxin receptor 2,C7orf1,hRVP1,...

 Human HEK293 Cells
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-3 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 24.7 kDa and the accession number is O15551.
TMPH-01102 Claudin-3 Protein, Human, Recombinant (B2M & His)

Rat ventral prostate.1 protein homolog,hRVP1,CPE-receptor 2,...

 Human E. coli
Claudin-3 Protein, Human, Recombinant (B2M & His) is expressed in E. coli.
TMPH-01101 Claudin-3 Protein, Human, Recombinant (Cell-Free, His)

Clostridium perfringens enterotoxin receptor 2,CPE-receptor ...

 Human E. coli
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-3 Protein, Human, Recombinant (Cell-Free, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 26.1 kDa and the accession number is O15551.
TMPY-06902 Claudin-9 Protein, Human, Recombinant

Human HEK293 Cells
Claudin-9 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 22.9 kDa and the accession number is O95484.
TMPY-06798 Claudin-9 Protein, Human, Recombinant (His & Avi), Biotinylated

Human HEK293 Cells
Claudin-9 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 22.44 kDa and the accession number is O95484.

重组蛋白

Claudin-6 Protein, Human, Recombinant
Cat.No: TMPY-06586
Species: Human
Expression System: HEK293 Cells
Claudin-6 Protein, Human, Recombinant (GFP & His)
Cat.No: TMPY-06965
Species: Human
Expression System: HEK293 Cells
Claudin-6 Protein, Human, Recombinant (His & FLAG)
Cat.No: TMPY-06805
Species: Human
Expression System: HEK293 Cells
Claudin-6 Protein, Human, Recombinant, Fluorescent,VLP
Cat.No: TMPY-06766
Species: Human
Expression System: HEK293 Cells
Claudin-18.2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01029
Species: Human
Expression System: E. coli
Claudin-18.2 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-01027
Species: Human
Expression System: E. coli
Claudin-6 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06851
Species: Human
Expression System: HEK293 Cells
Claudin-18.2 Protein, Human, Recombinant (Twin strep & Flag)
Cat.No: TMPJ-01028
Species: Human
Expression System: HEK293 Cells
Claudin-11 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-03175
Species: Human
Expression System: HEK293 Cells
Claudin-18 Protein, Human, Recombinant (His & Strep)
Cat.No: TMPY-06942
Species: Human
Expression System: HEK293 Cells
Claudin-18.2 Protein-VLP, Human, Recombinant
Cat.No: TMPY-06596
Species: Human
Expression System: HEK293 Cells
Claudin-18 Protein, Human, Recombinant (CLDN18.2), Fluorescent
Cat.No: TMPY-06822
Species: Human
Expression System: HEK293 Cells
Claudin-6 Protein-VLP, Cynomolgus, Recombinant
Cat.No: TMPK-00667
Species: Cynomolgus
Expression System: HEK293 Cells
Claudin-18.1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01026
Species: Human
Expression System: E. coli
Claudin-6 Protein-VLP, Human, Recombinant
Cat.No: TMPK-00904
Species: Human
Expression System: HEK293 Cells
Claudin-18 Protein, Human, Recombinant (CLDN18.1)
Cat.No: TMPY-06828
Species: Human
Expression System: HEK293 Cells
Claudin-6 Protein-VLP, Mouse, Recombinant
Cat.No: TMPK-01249
Species: Mouse
Expression System: HEK293 Cells
Claudin-18 Protein-VLP, Cynomolgus, Recombinant (His)
Cat.No: TMPH-02423
Species: Cynomolgus
Expression System: HEK293 Cells
Claudin-18 Protein-VLP, Mouse, Recombinant (His)
Cat.No: TMPH-02586
Species: Mouse
Expression System: HEK293 Cells
Claudin-9 Protein-VLP, Human, Recombinant (His)
Cat.No: TMPH-01104
Species: Human
Expression System: HEK293 Cells
Claudin-4 Protein-VLP, Human, Recombinant
Cat.No: TMPK-00710
Species: Human
Expression System: HEK293 Cells
Claudin-3 Protein-VLP, Human, Recombinant (His)
Cat.No: TMPH-01103
Species: Human
Expression System: HEK293 Cells
Claudin-3 Protein, Human, Recombinant (B2M & His)
Cat.No: TMPH-01102
Species: Human
Expression System: E. coli
Claudin-3 Protein, Human, Recombinant (Cell-Free, His)
Cat.No: TMPH-01101
Species: Human
Expression System: E. coli
Claudin-9 Protein, Human, Recombinant
Cat.No: TMPY-06902
Species: Human
Expression System: HEK293 Cells
Claudin-9 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06798
Species: Human
Expression System: HEK293 Cells
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