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Cat. No. | Product Name | Target | Signaling Pathways |
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T65070 |
Chenodeoxycholic Acid (sodium salt)
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Chenodeoxycholic Acid (sodium salt) 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65070,CAS号为 2646-38-0。 | |||
T81207 | SARS-CoV-2-IN-64 | SARS-CoV | Microbiology/Virology |
SARS-CoV-2-IN-64(compound 9)为鹅去氧胆酸衍生物,对SARS-CoV-2刺突糖蛋白具有显著抑制作用。 | |||
T37854 |
Cholic Acid 7-sulfate
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Cholic acid 7-sulfate is a metabolite of the primary bile acid cholic acid.[1],[2] It is produced by conjugation of a sulfate group with the hydroxy group at position 7 of cholic acid in the liver and gut. Fecal levels of cholic acid 7-sulfate are increased in male, but not female, mice fed a diet supplemented with cholic acid or chenodeoxycholic acid.[2] | |||
T83858 |
Tauro-Obeticholic Acid sodium
Tauro-6-Ethylchenodeoxycholic Acid,Tauro-6-Ethyl-CDCA,Obeticholic Acid Taurine Conjugate,Tauro-OCA,T-ECDCA |
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陶氏奥贝胆酸是奥贝胆酸的活性代谢物,属于法尼索德X受体(FXR)激动剂并且是熊脱氧胆酸的半合成衍生物。陶氏奥贝胆酸通过在肝脏中与牛磺酸结合形成,但可以通过肠道微生物被再次转换回奥贝胆酸。 |
Cat. No. | Product Name | Target | Signaling Pathways |
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T0847 |
Chenodeoxycholic acid
CDCA,鹅去氧胆酸,Chenodiol |
Potassium Channel; FXR; Endogenous Metabolite; Autophagy | Autophagy; Membrane transporter/Ion channel; Metabolism |
Chenodeoxycholic acid (CDCA) 是一种胆汁酸,通常与甘氨酸或牛磺酸结合。它作为清洁剂溶解脂肪以供肠道吸收,并被小肠重新吸收。它被用作利胆剂、利胆泻药,以及预防或溶解胆结石。 | |||
T36563 |
(E)-Guggulsterone
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Bile acids are essential for solubilization and transport of dietary lipids, are the major products of cholesterol catabolism, and are physiological ligands for farnesoid X receptor (FXR), a nuclear receptor that regulates genes involved in lipid metabolism.1They are also inherently cytotoxic, as physiological imbalance contributes to increased oxidative stress.2,3Bile acid-controlled signaling pathways are promising novel targets to treat such metabolic diseases as obesity, type II diabetes, hy... |