Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10729 |
Cdc7-IN-7
|
CDK | Cell Cycle/Checkpoint |
Cdc7-IN-7 (compound I-E) 是一种有效的 Cdc7 激酶抑制剂。 | |||
T10727 |
Cdc7-IN-5
|
CDK | Cell Cycle/Checkpoint |
Cdc7-IN-5 是一种有效的 Cdc7 激酶抑制剂。Cdc7 是一种丝氨酸苏氨酸蛋白激酶酶,在细胞周期中对 DNA 复制的启动至关重要。 | |||
T23867 |
Cdc7-IN-7c
Cdc7 inhibitor-7c,Cdc7 inhibitor 7c,Cdc7 IN 7c |
CDK | Cell Cycle/Checkpoint |
Cdc7-IN-7c (Cdc7 inhibitor-7c) 具有抗肿瘤活性,对肝癌,肺癌,肾癌,脑癌,宫颈癌有抑制作用。 | |||
T10724 |
Cdc7-IN-1
|
CDK | Cell Cycle/Checkpoint |
Cdc7-IN-1 is a highly selective and ATP competitive inhibitor of Cdc7 kinase (IC50: 0.6 nM at 1 mM ATP). It potently inhibits Cdc7 activity in cancer cells and effectively induces cell death. | |||
T10726 |
Cdc7-IN-4
|
Others | Others |
Cdc7-IN-4 is a potent inhibitor of Cdc7 kinase. | |||
T10725 |
Cdc7-IN-3
|
Others | Others |
Cdc7-IN-3 is a potent inhibitor of Cdc7 kinase. | |||
T3352 |
XL413
|
cholecystokinin; Casein Kinase; Pim; CDK | Cell Cycle/Checkpoint; Chromatin/Epigenetic; GPCR/G Protein; JAK/STAT signaling; Metabolism; Stem Cells |
XL413 是一种口服生物可利用的细胞分裂周期 7 同源物 (CDC7) 激酶抑制剂,具有潜在的抗肿瘤活性,IC50值为 3.4 nM。它对 pMCM 的 EC50值为 118 nM,对 CK2 和 PIM1 的 IC50值分别为 215 和 42 nM。 |