Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T60696 |
CXCR2 antagonist 8
|
||
CXCR2 antagonist 8 是可用于研究胰岛素抵抗的,CXCR2受体的选择性拮抗剂。 | |||
T1955 |
SB225002
|
CXCR | Autophagy; GPCR/G Protein; Immunology/Inflammation |
SB225002 是一种有效的选择性 CXCR2 拮抗剂,抑制白介素 IL-8 与 CXCR2 的结合,IC50为 22 nM。 | |||
T5193 |
Danirixin
GSK1325756 |
CXCR | Autophagy; GPCR/G Protein; Immunology/Inflammation |
Danirixin (GSK1325756) 是一种选择性可逆的CXCR2拮抗剂,抑制 CXCL8 的IC50值为 12.5 nM。 | |||
T11179 |
Elubrixin
SB-656933 |
IL Receptor; CXCR | Autophagy; GPCR/G Protein; Immunology/Inflammation |
Elubrixin (SB-656933) 是一种有效和特异性的 CXCR2 和 IL-8 受体拮抗剂。 Elubrixin 可用于炎症性疾病的研究,例如炎症性肠病和气道炎症。 | |||
T27255 |
Elubrixin HCl
SB656933,SB-656933AAF,SB-656933-AAF,SB 656933,SB-656933 AAF,SB-656933 |
||
Elubrixin is a interleukin 8 inhibitor and CXCR2 selective antagonist. | |||
T41121 |
Elubrixin tosylate
SB-656933 tosylate,Elubrixin tosylate |
||
Elubrixin tosylate (SB-656933 tosylate) is a high-potency, selective, competitive, and reversible CXCR2 antagonist, as well as an antagonist of the IL-8 receptor. It effectively inhibits upregulation of neutrophil CD11b (with an IC50 of 260.7 nM) and shape change (with an IC50 of 310.5 nM). This compound holds promise for the study of inflammatory diseases, including inflammatory bowel disease and airway inflammation. |