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Cat. No. Product Name Target Signaling Pathways
T10828 CK2/PIM1-IN-1

Others Others
CK2/PIM1-IN-1 is an inhibitor of CK2 and PIM1 (IC50s: 3.787 μM and 4.327 μM). It is developed for the research of proliferative disorders such as cancer, as well as other kinase-associated conditions.
T10827 CK2/ERK8-IN-1

TMCB

Apoptosis; ERK; Casein Kinase; Pim; DYRK Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; JAK/STAT signaling; MAPK; Metabolism; Stem Cells; Tyrosine Kinase/Adaptors
CK2/ERK8-IN-1 (TMCB) 是一种酪蛋白激酶 2 (CK2) (Ki 为 0.25 µM) 和 ERK8 (MAPK15, ERK7) 的双重抑制剂,IC50 均为 0.50 μM。CK2/ERK8-IN-1 也与 PIM1,HIPK2 和 DYRK1A 结合,Ki 值分别为 8.65 µM,15.25 µM 和 11.9 µM。

化合物

CK2/PIM1-IN-1
Cat.No: T10828
Synonym:
Target: Others
CK2/ERK8-IN-1
Cat.No: T10827
Synonym: TMCB
Target: Apoptosis, ERK, Casein Kinase, Pim, DYRK
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