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Search Results for " cd154 "

4

抑制剂 & 化合物

15

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T73865 (Rac)-BIO8898

(Rac)-BIO8898 是一种 CD40-CD154共刺激相互作用抑制剂。(Rac)-BIO8898 抑制 CD154CD40-Ig 结合,IC50为 25 μM。
T73866 BIO8898

BIO8898 是一种有效的 CD40-CD154抑制剂。BIO8898 抑制可溶性 CD40L 与 CD40-Ig 的结合,IC50值为 25 µM。BIO8898 抑制 CD40L 诱导的细胞凋亡(apoptosis)。
T30669 C.I. Mordant Brown 1

NSC-326197,NSC 326197,NSC326197

C.I. Mordant Brown 1 是一种偶氮染料,λmax 为 373 nm、487 nm (2nd)。C.I. Mordant Brown 1 也可以抑制CD40-CD154 共刺激蛋白-蛋白互作。
T76834 Toralizumab

Toralizumab (IDEC-131) 是一种针对 CD40L (CD154)的人源化单克隆抗体 (mAb),由人 γ1 重链和人 kappa 轻链组成。Toralizumab 特异性结合 T 细胞上的人 CD40L,从而阻止 CD40信号传导。Toralizumab 是一种免疫抑制剂,具有用于活跃的系统性红斑狼疮 (SLE) 研究的潜力。

化合物

(Rac)-BIO8898
Cat.No: T73865
Synonym:
Target:
BIO8898
Cat.No: T73866
Synonym:
Target:
C.I. Mordant Brown 1
Cat.No: T30669
Synonym: NSC-326197,NSC 326197,NSC326197
Target:
Toralizumab
Cat.No: T76834
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-02022 CD40 Ligand Protein, Human, Recombinant (hFc)

HIGM1,IGM,gp39,CD40L,T-BAM,CD40 ligand,

Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.8 kDa and the accession number is P29965.
TMPY-05646 CD40 Ligand Protein, Human, Recombinant (hFc & Avi), Biotinylated

CD154,TRAP,CD40 ligand,gp39,h...

Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 44.7 kDa and the accession number is P29965.
TMPY-01758 CD40 Ligand Protein, Human, Recombinant (His)

IMD3,hCD40L,CD40L,TRAP,TNFSF5,IGM,HIGM1,gp...

Human E. coli
CD40 Ligand Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 17.7 kDa and the accession number is P29965.
TMPK-00154 CD40 Ligand Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated

IMD3,TNFSF5IMD3,TRAP,CD40LIGM,CD40 Ligand,...

Human HEK293 Cells
CD40 ligand or CD40L, also called CD154,  is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells. CD40 Ligand Prote...
TMPH-02439 CD40L Protein, Rhesus macaque, Recombinant (His)

CD40L,TNFSF5,CD40LG,CD154

Rhesus E. coli
CD40L Protein, Rhesus macaque, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 28.5 kDa and the accession number is P63304.
TMPK-00860 CD40 Ligand Protein, Mouse, Recombinant (monomeric hFc)

IMD3,CD40LG,CD40L,IGM,TRAP,T-BAM,gp39,HIGM...

Mouse HEK293 Cells
CD40 ligand or CD40L, also called CD154,  is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells. CD40 Ligand Prote...
TMPY-02793 CD40 Ligand Protein, Mouse, Recombinant (hFc)

gp39,CD40 ligand,IGM,Cd40l,CD40-L...

Mouse HEK293 Cells
CD40 Ligand Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.4 kDa and the accession number is P27548.
TMPK-01398 CD40 Ligand Trimer Protein, Human, Recombinant (hFc)

CD40 Ligand,CD40LIGM,IGM,gp39,TNFSF5,TRAP,...

Human HEK293 Cells
CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.
TMPY-06687 CD40 Ligand Protein, Mouse, Recombinant (His)

IGM,IMD3,TRAP,Ly62,CD40-L,Tnfsf5,CD154...

Mouse HEK293 Cells
CD40 Ligand Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.37 kDa and the accession number is P27548.
TMPJ-00150 CD40 Ligand Protein, Human, Recombinant (Mammalian)

CD40LG,Tumor Necrosis Factor Ligand Superfamily Mem...

Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (Mammalian) is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-18 KDa and the accession number is P29965.
TMPJ-00151 CD40 Ligand Protein, Human, Recombinant

CD40LG,CD40 Ligand,TRAP,TNF-Related Activa...

Human E. coli
CD40 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 KDa and the accession number is P29965.
TMPJ-00152 CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated

CD40 Ligand,TNF-Related Activation Protein,CD

Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-6xHis-Avi tag. The predicted molecular weight is 23-28 KDa and the accession number is P29965.
TMPJ-00153 CD40 Ligand Protein, Human, Recombinant (His & Flag)

CD40LG,Tumor Necrosis Factor Ligand Superfamily Mem...

Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 19-24 KDa and the accession number is P29965.
TMPK-00170 CD40 Protein, Human, Recombinant (aa 21-193, His & Avi), Biotinylated

CD40 antigen,  TNFRSF5,CD40 molecule,C...

Human HEK293 Cells
CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.CD40 molecule is a potential target for cancer immunotherapy. There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells.
TMPJ-00920 CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)

TNFSF5,Tumor necrosis factor ligand superfamily member 5,

Mouse HEK293 Cells
CD40 Ligand, also known as TNFSF5, CD154, is a type II transmembrane glycoprotein member of the TNF superfamily. Mature mouse CD40 Ligand consists of a 22 amino acid (aa) cytoplasmic domain, a transmembrane segment, and a 214 aa extracellular region. CD40 Ligand is expressed as a homotrimer on platelets and activated T cells and B cells. It is up­regulated following stimulation of basophils, eosinophils, fibroblasts, mast cells, monocytes, natural killer cells, vascular endothelial cells, and sm...

重组蛋白

CD40 Ligand Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02022
Species: Human
Expression System: HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05646
Species: Human
Expression System: HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His)
Cat.No: TMPY-01758
Species: Human
Expression System: E. coli
CD40 Ligand Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
Cat.No: TMPK-00154
Species: Human
Expression System: HEK293 Cells
CD40L Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPH-02439
Species: Rhesus
Expression System: E. coli
CD40 Ligand Protein, Mouse, Recombinant (monomeric hFc)
Cat.No: TMPK-00860
Species: Mouse
Expression System: HEK293 Cells
CD40 Ligand Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02793
Species: Mouse
Expression System: HEK293 Cells
CD40 Ligand Trimer Protein, Human, Recombinant (hFc)
Cat.No: TMPK-01398
Species: Human
Expression System: HEK293 Cells
CD40 Ligand Protein, Mouse, Recombinant (His)
Cat.No: TMPY-06687
Species: Mouse
Expression System: HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (Mammalian)
Cat.No: TMPJ-00150
Species: Human
Expression System: HEK293 Cells
CD40 Ligand Protein, Human, Recombinant
Cat.No: TMPJ-00151
Species: Human
Expression System: E. coli
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00152
Species: Human
Expression System: HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His & Flag)
Cat.No: TMPJ-00153
Species: Human
Expression System: HEK293 Cells
CD40 Protein, Human, Recombinant (aa 21-193, His & Avi), Biotinylated
Cat.No: TMPK-00170
Species: Human
Expression System: HEK293 Cells
CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)
Cat.No: TMPJ-00920
Species: Mouse
Expression System: HEK293 Cells
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