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Cat. No.	Product Name	Target	Signaling Pathways
T10714	CCR5 antagonist 1	HIV Protease; CCR	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	CCR5 antagonist 1 is a CCR5 antagonist extracted from WO 2004054974 A2. It can inhibit HIV replication.
T6016	Maraviroc Celsentri,马拉维若,UK-427857,Selzentry	HIV Protease; CCR	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Maraviroc (Selzentry) 是一种 C-C 趋化因子受体 5 拮抗剂，具有抑制HIV 的活性。
TQ0297	Cenicriviroc TAK-652,TBR-652	HIV Protease; CCR	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Cenicriviroc (TAK-652) 是一种可口服的CCR2/CCR5拮抗剂，可抑制 HIV-1 和 HIV-2，具有抗炎、抗感染作用。
T71665	INCB-9471	HIV Protease; CCR	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	INCB-9471 是一种 CCR5 拮抗剂，具有抗HIV活性，抑制 HIV-1 gp120 之间的相互作用。
T7499	TAK-779 Takeda 779	HIV Protease; CXCR; CCR	Autophagy; GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	TAK-779 (Takeda 779) 是一种非肽类CCR5和CXCR3 拮抗剂，对CCR5的Ki 值为 1.1 nM，并选择性抑制R5 HIV-1。
T3435	Vicriviroc maleate 维立韦罗马来酸盐,SCH-D (maleate),SCH-417690 (maleate)	HIV Protease; CCR	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	Vicriviroc maleate (SCH-417690 (maleate)) 是一种可口服，可透过血脑屏障的 CCR5选择性拮抗剂，同时抑制外周血单核细胞中的 HIV-1 的活性。
T2375	BX471 BX 471,BX-471,ZK-811752	CCR	Immunology/Inflammation; Microbiology/Virology
	BX471 (BX 471) 是可口服的非多肽 CCR1选择性拮抗剂，Ki 值为 1 nM，对其选择性是对 CCR2、CCR5 和 CXCR4 的 250 倍。
T28171	Nifeviroc TD-0232,TD 0232,尼非韦罗,TD0232
	Nifeviroc, a CCR5 antagonist, is used potentially for treatment of inflammatory responses to HIV type-1 infection.
T23770	B07 hydrochloride B 07 HCl,B-07 HCl,B-07 hydrochloride,B07 HCl,B 07 hydrochloride
	B07 hydrochloride is a CCR5 antagonist-based inhibitor of HIV-1 entry.
T10756	Cenicriviroc Mesylate TBR-652 Mesylate,TAK-652 Mesylate	CCR	Immunology/Inflammation; Microbiology/Virology
	Cenicriviroc Mesylate is a dual CCR2/CCR5 antagonist, also inhibits both HIV-1 and HIV-2 with anti-inflammatory and antiinfective activity.
T28381	PF-232798 PF-00232798,PF 00232798,PF00232798
	PF-232798 is a second generation oral CCR5 antagonist with potent broad-spectrum anti-HIV-1 activity.
T76567	Met-RANTES (human)
	Met-RANTES (human) 为一部分CCR5拮抗剂，能够降低血液单核细胞向肝脏浸润的程度。
T69582	AMD-3451 free base
	AMD-3451 free base is a dual CCR5/CXCR4 antagonist which may be useful in the treatment of a wide variety of R5, R5/X4, and X4 strains of human immunodeficiency virus type 1 (HIV-1) and HIV-2. AMD3451 is the first low-molecular-weight anti-HIV agent with selective HIV coreceptor, CCR5 and CXCR4, interaction.
T14845	BX471 hydrochloride ZK-811752 hydrochloride	Others	Others
	BX471 hydrochloride (ZK-811752 hydrochloride) is a potent, selective non-peptide CCR1 antagonist (Ki: 1 nM for human CCR1). It shows 250-fold selectivity for CCR1 over CCR2, CCR5, and CXCR4.
T14208	AMD 3465 GENZ-644494	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM). However, it has no effect on CCR5-using (R5) viruses. AMD 3465 (GENZ-644494) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC

化合物

CCR5 antagonist 1

Cat.No: T10714

Target: HIV Protease, CCR

Cat.No: T6016

Synonym: Celsentri,马拉维若,UK-427857,Selzentry

Target: HIV Protease, CCR

Cat.No: TQ0297

Synonym: TAK-652,TBR-652

Target: HIV Protease, CCR

Cat.No: T71665

Target: HIV Protease, CCR

Cat.No: T7499

Synonym: Takeda 779

Target: HIV Protease, CXCR, CCR

Vicriviroc maleate

Cat.No: T3435

Synonym: 维立韦罗马来酸盐,SCH-D (maleate),SCH-417690 (maleate)

Target: HIV Protease, CCR

Cat.No: T2375

Synonym: BX 471,BX-471,ZK-811752

Target: CCR

Cat.No: T28171

Synonym: TD-0232,TD 0232,尼非韦罗,TD0232

B07 hydrochloride

Cat.No: T23770

Synonym: B 07 HCl,B-07 HCl,B-07 hydrochloride,B07 HCl,B 07 hydrochloride

Cenicriviroc Mesylate

Cat.No: T10756

Synonym: TBR-652 Mesylate,TAK-652 Mesylate

Target: CCR

Cat.No: T28381

Synonym: PF-00232798,PF 00232798,PF00232798

Met-RANTES (human)

Cat.No: T76567

AMD-3451 free base

Cat.No: T69582

BX471 hydrochloride

Cat.No: T14845

Synonym: ZK-811752 hydrochloride

Target: Others

Cat.No: T14208

Synonym: GENZ-644494

Target: HIV Protease

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