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Search Results for " cbs "

Targets Recommended: Lipoxygenase

10

抑制剂 & 化合物

1

天然产物

5

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T68037L	CBS-1114 HCl N-Phenylbenzamidrazone hydrochloride,cbs-1114 HCl(46721-85-1 Free base)	Lipoxygenase	Metabolism
	CBS-1114 HCl (N-Phenylbenzamidrazone hydrochloride) 是一种5-脂氧合酶抑制剂，是一种良好眼睛渗透型号的抗炎化合物。CBS-1114 HCl 可以保持和改善心脏功能，减轻心功能障碍，以及减少患有心血管疾病的受试者的心外膜脂肪组织和/或心包脂肪组织。
T33584	Namirotene CBS 211A,Cbs 211 A	Others	Others
	Namirotene (CBS 211A) 是一种蛋白质生物合成抑制剂，是一种人工合成的维甲酸类似物，可用于研究角膜疾病、角膜溃疡和干眼综合征。
T14885	CBS9106 Felezonexor,SL-801	CRM1	Membrane transporter/Ion channel
	CBS9106 (SL-801) 是一种可逆的口服 CRM1 抑制剂，具有降解 CRM1 和抗肿瘤活性。CBS9106 可抑制 CRM1 依赖性核输出，降低 CRM1 蛋白水平。CBS9106 抑制肿瘤生长并延长携带肿瘤异种移植物的小鼠的存活时间。
T8793	CBS1117	Influenza Virus	Microbiology/Virology
	CBS1117 是一种病毒进入抑制剂，对甲型流感病毒 A/Puerto Rico/8/34 的 IC50为 70 nM。它干扰血凝素介导的融合过程。
T26964	CBS-3595 CBS3595
	CBS-3595 is a potent and dual Inhibitor of p38α MAPK/PDE-4 with a superior profile regarding its anti-inflammatory effects. CBS-3595 features moderate inhibition of p38α MAPK and PDE-4 in the higher nanomolar range in combination with excellent kinetic pr
T6130	Skepinone-L CBS3830	p38 MAPK; Autophagy	Autophagy; MAPK
	Skepinone-L (CBS3830) 是一种选择性 p38 丝裂原活化蛋白激酶抑制剂。
T68413	CBS1194
	CBS1194 is a novel antiviral agent against influenza A virus (IAV), and is more specifically, a group 2 IAV fusion inhibitor. CBS1194 prevents membrane fusion of the virus through the inhibition of the conformational change of hemagglutinin (HA). CBS1194 causes steric hinderance that prevents the rearrangement of the HA that would normally be induced by low-pH, by fitting into the pocket by the fusion peptide.
T68037	cbs-1114
	cbs-1114 在生命科学相关研究中具有广泛的应用。
T80233	p53 CBS p53 Consensus binding sequence
	p53 CBS（p53共有DNA结合位点）是一种具备生物活性的肽类化合物。
T10939	D,L-Cystathionine dihydrochloride	Others	Others
	D,L-Cystathionine dihydrochloride is an intermediate in the synthesis of cysteine, which acts from the isotype of cysteine-β-synthase (CBS) produced by leucine and serine. Derived from cysteine. DL-cysteine contains a cysteine (βC-S) carbon-sulfur bond.

化合物

Cat.No: T68037L

Synonym: N-Phenylbenzamidrazone hydrochloride,cbs-1114 HCl(46721-85-1 Free base)

Target: Lipoxygenase

Cat.No: T33584

Synonym: CBS 211A,Cbs 211 A

Target: Others

Cat.No: T14885

Synonym: Felezonexor,SL-801

Target: CRM1

Cat.No: T8793

Target: Influenza Virus

Cat.No: T26964

Synonym: CBS3595

Cat.No: T6130

Synonym: CBS3830

Target: p38 MAPK, Autophagy

Cat.No: T68413

Cat.No: T68037

Cat.No: T80233

Synonym: p53 Consensus binding sequence

D,L-Cystathionine dihydrochloride

Cat.No: T10939

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN1569	Deoxylapachol	Antifection; Antifungal	Microbiology/Virology
	Deoxylapachol 是新西兰褐藻Landsburgia quercifolia 的主要细胞毒性成分，有抗真菌和抗癌活性。

天然产物

Cat.No: TN1569

Target: Antifection, Antifungal

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02615	CBS Protein, Mouse, Recombinant (His) Cystathionine beta-synthase,Serine sulfhydrase,Beta-thionase...	Mouse	E. coli
	Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine. Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons.
TMPH-01175	CBS Protein, Human, Recombinant (His) Serine sulfhydrase,Cystathionine beta-synthase,Beta-thionase...	Human	P. pastoris (Yeast)
	CBS Protein, Human, Recombinant (His) is expressed in Yeast.
TMPH-01174	CBS Protein, Human, Recombinant (E. coli, His) Serine sulfhydrase,Beta-thionase,CBS,Cystathionine ...	Human	E. coli
	CBS Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.
TMPH-03013	HRP1 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc & SUMO)	Mycobacterium tuberculosis	E. coli
	Unlike some other CBS-domain containing proteins does not seem to bind AMP.
TMPH-02246	TGS1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.

重组蛋白

CBS Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02615

Species: Mouse

Expression System: E. coli

CBS Protein, Human, Recombinant (His)

Cat.No: TMPH-01175

Species: Human

Expression System: P. pastoris (Yeast)

CBS Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01174

Species: Human

Expression System: E. coli

HRP1 Protein, Mycobacterium tuberculosis, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-03013

Species: Mycobacterium tuberculosis

Expression System: E. coli

TGS1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02246

Species: Human

Expression System: E. coli

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