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Targets Recommended: CaMK

2

抑制剂 & 化合物

3

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T3650 STO-609 acetate

CaMK Neuroscience
STO-609 acetate 是选择性的、细胞可渗透的 Ca2+-钙调蛋白依赖性蛋白激酶激酶抑制剂(Ki:80/15 ng/ml,对于 CaM-KKα/KKβ);竞争 ATP 结合位点。它比 CaMK1/2/4、PKC、MLCK、PKA 和 p42 MAPK 显示 > 80 倍的选择性。
T3546 STO-609

STO 609

CaMK; AMPK; Autophagy Autophagy; Chromatin/Epigenetic; Neuroscience; PI3K/Akt/mTOR signaling
STO-609 是一种特异性和细胞渗透性的 Ca2+/钙调蛋白依赖性蛋白激酶激酶抑制剂,用于重组 CaM-KKα 和 CaM-KKβ,Ki 值分别为 80 和 15 ng/mL。它抑制 Hela 细胞溶解物中的 AMP 活化蛋白激酶激酶活性,IC50值约为 0.02 g/ml。

化合物

STO-609 acetate
Cat.No: T3650
Synonym:
Target: CaMK
STO-609
Cat.No: T3546
Synonym: STO 609
Target: CaMK, AMPK, Autophagy
Cat. No. Product Name Species Expression System
TMPJ-00240 CAMK1 Protein, Human, Recombinant (His)

CaM Kinase I Alpha,CaMKI-α,CaM Kinase I,CAMK

Human HEK293 Cells
Calcium/Calmodulin-Dependent Protein Kinase Type 1 (CAMK1) belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family, and CaMK subfamily. CAMK1 contains one protein kinase domain and widely expressed. CAMK1 is phosphorylated by CaMKK1 and CaMKK2 on Thr-177. CAMK1 regulates transcription activators activity, cell cycle, hormone production, cell differentiation, actin filament organization, and neurite outgrowth. CAMK1 plays a role in K+ and ANG2-mediated regulation of the aldo...
TMPY-04423 CAMKI gamma/CAMK1G Protein, Human, Recombinant (His & GST)

VWS1,RP1-272L16.2,calcium/calmodu...

Human Baculovirus Insect Cells
Calmodulin-Dependent Protein Kinase (CaM Kinase) is a kind of protein phosphorylate multiple downstream targets. Concentration of cytosolic calcium functions as a second messenger that mediates a wide range of cellular responses. Calcium binds to calcium binding proteins (calmodulin/CaM) and stimulates the activity of a variety of enzymes, including CaM kinases referred to as CaM-kinases (CaMKs), such as CaMKI, CaMKII, CaMKIV and CaMKK. Calmodulin-dependent protein kinase CL3/CaMKIγ is a membera...
TMPY-04381 CAMK1D Protein, Human, Recombinant (GST)

calcium/calmodulin-dependent protein kinase ID,CaMK...

Human Baculovirus Insect Cells
CAMK1D Protein, Human, Recombinant (GST) is expressed in Baculovirus insect cells with GST tag. The predicted molecular weight is 69 kDa and the accession number is Q8IU85-1.

重组蛋白

CAMK1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00240
Species: Human
Expression System: HEK293 Cells
CAMKI gamma/CAMK1G Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04423
Species: Human
Expression System: Baculovirus Insect Cells
CAMK1D Protein, Human, Recombinant (GST)
Cat.No: TMPY-04381
Species: Human
Expression System: Baculovirus Insect Cells
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