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9

抑制剂 & 化合物

3

天然产物

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Cat. No. Product Name Target Signaling Pathways
T4309 CIL56

CA3

Ferroptosis; ROS Apoptosis; Immunology/Inflammation
CIL56 (CA3) 是一种选择性铁死亡诱导剂,可通过产生铁依赖性活性氧来诱导细胞铁死亡。
T61077 UNC-CA359

UNC-CA359 is a highly potent inhibitor of the epidermal growth factor receptor (EGFR), demonstrating an IC50 value of 18 nM. With strong anti-tumor activity, UNC-CA359 holds significant potential for chordoma research [1].
TP1895L1 KYL acetate(676657-00-4 free base)

Ephrin Receptor Tyrosine Kinase/Adaptors
KYL acetate(676657-00-4 free base) 是EphA4受体酪氨酸激酶抑制剂(Kd = 0.8 μM);抑制 EphA4-EphrinA5 相互作用 (IC50 = 6.34 μM)。防止 AβO 诱导的突触损伤、树突棘丢失并防止海马 CA3-CA1 传输中 LTP 的阻断。在细胞培养基中表现出较长的半衰期(在 PC3 和 C2C12 培养基中分别为 8 和 12 小时)。它有神经保护作用。
T78062 Dendrotoxin K TFA

Potassium Channel Membrane transporter/Ion channel
Dendrotoxin K TFA是一种特异的Kv1.1通道阻滞剂,通过时间依赖性方式调控突触前尖峰波形成,影响到谷氨酸在CA3神经元的释放。
T76187 Dendrotoxin K

Dendrotoxin K,一种Kv1.1通道阻滞剂,通过时间依赖性地控制突触前尖峰波,从而将谷氨酸释放入CA3神经元中。
T27326 FK960

FK 59960,FK-960,FK-59960,FK59960

FK962 is an enhancer of somatostatin release, which exerts cognitive-enhancing actions in rats. FK960 increases synaptic density in the hippocampal CA3 region of aged rats.
T76358 Neuropeptide Y (1-24) (human)

Neuropeptide Y (1-24) (human) 是一种神经肽,它能够抑制大鼠输精管电刺激引发的抽搐反应,同时在体内刺激 N-methyl-D-aspartate (NMDA) 促使大鼠海马背侧 CA3 区神经元激活。
TP1895 KYL peptide

KYL

EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM); inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM). Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a lon
T71142 Tebuconazole-d9

Tebuconazole-d9 is intended for use as an internal standard for the quantification of tebuconazole by GC- or LC-MS. Tebuconazole is a triazole fungicide that is active against both seed and foliar fungi. It inhibits 14α-demethylase isolated from U. maydis and S. bicolor with IC50 values of 0.05 and 0.16 nM, respectively. It inhibits the androgenic effect of the androgen receptor agonist DHT (IC20 = 2.89 µM) and is cytotoxic (EC20 = 38.9 µM) in an MDA-kb2 assay. Tebuconazole (50 and 100 mg/kg per...

化合物

CIL56
Cat.No: T4309
Synonym: CA3
Target: Ferroptosis, ROS
UNC-CA359
Cat.No: T61077
Synonym:
Target:
KYL acetate(676657-00-4 free base)
Cat.No: TP1895L1
Synonym:
Target: Ephrin Receptor
Dendrotoxin K TFA
Cat.No: T78062
Synonym:
Target: Potassium Channel
Dendrotoxin K
Cat.No: T76187
Synonym:
Target:
FK960
Cat.No: T27326
Synonym: FK 59960,FK-960,FK-59960,FK59960
Target:
Neuropeptide Y (1-24) (human)
Cat.No: T76358
Synonym:
Target:
KYL peptide
Cat.No: TP1895
Synonym: KYL
Target:
Tebuconazole-d9
Cat.No: T71142
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T9143 D-Isoleucine

(2R,3R)-2-Amino-3-methylpentanoic acid,D-异亮氨酸,(R)-Isoleucine

Others Others
D-Isoleucine ((2R,3R)-2-Amino-3-methylpentanoic acid) 是一种异亮氨酸立体异构体,是 Asc-1 反转运蛋白的选择性激活剂。它能够释放内源性 D-丝氨酸,提高海马 CA1-CA3 的长期增效作用。
T14011 2-Arachidonoylglycerol

Cannabinoid Receptor; Endogenous Metabolite GPCR/G Protein; Metabolism
2-Arachidonoylglycerol 属于人内源性代谢物,是中枢神经系统中的一种内源性大麻素配体。
T20493 Palmitone

NSC-953,NSC953,NSC 953

In the CA3 hippocampal region, Palmitone against pentylenetetrazole-caused neuronal damage.

天然产物

D-Isoleucine
Cat.No: T9143
Synonym: (2R,3R)-2-Amino-3-methylpentanoic acid,D-异亮氨酸,(R)-Isoleucine
Target: Others
2-Arachidonoylglycerol
Cat.No: T14011
Synonym:
Target: Cannabinoid Receptor, Endogenous Metabolite
Palmitone
Cat.No: T20493
Synonym: NSC-953,NSC953,NSC 953
Target:
TargetMol Loading
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