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Search Results for " c3a "

Targets Recommended: Complement System

10

抑制剂 & 化合物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T38287	C3a Receptor Agonist C3a receptor agonist 1,C3a受体激动剂,Complement 3a Receptor Agonist	Complement System	Immunology/Inflammation
	C3a Receptor Agonist (C3a receptor agonist 1) 结合免疫系统补体途径中的G 蛋白偶联C3a 受体(C3aRs)。在肠缺血再灌注损伤模型中，C3aR 的激活可防止中性粒细胞动员。C3aRs 在成年小鼠的神经祖细胞和未成熟神经元上表达。C3a 在体外刺激神经祖细胞的分化。
T7497L1	C3a 70-77 acetate C3a 70-77 acetate (63555-63-5 Free base)	Others	Others
	C3a 70-77 acetate 是对应于 C3a 的 COOH 末端的八肽乙酸酯，具有 C3a 的特异性和 1% 至 2% 的生物活性。
T7497L	C3a 70-77 2TFA(63555-63-5(free base)) Complement 3a (70-77)	Complement System	Immunology/Inflammation
	C3a 70-77 2TFA(63555-63-5(free base)) (Complement 3a (70-77)) 是对应于 C3a 的 COOH 末端的八肽。
T7497	C3a (70-77) Complement 3a (70-77),C3a 70-77	Complement System	Immunology/Inflammation
	C3a (70-77) 是对应于 C3a 的 COOH 末端的八肽。
TP1193	C3a (70-77) TFA (63555-63-5 free base) C3a (70-77) TFA,Complement 3a (70-77) (TFA)
	C3a (70-77) TFA (Complement 3a (70-77) TFA) is a COOH-terminal fragment of the C3a anaphylatoxin peptide.
T75966	C3a (70-77) (TFA)
	C3a (70-77) TFA (Complement 3a (70-77) TFA) 为COOH末端对应C3a的八肽，具有C3a的特异性且生物活性约为1至2％。
T9316	JR14a 5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride	Complement System	Immunology/Inflammation
	JR14a (5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride) 是补体C3a 受体噻吩拮抗剂，可抑制 C3aR 介导的炎症，对人 C3a 受体的选择性高于 C5a 受体。
T12851	SB290157 trifluoroacetate	Complement System	Immunology/Inflammation
	SB290157 trifluoroacetate 是一种选择性 C3a 受体拮抗剂，IC50值为200 nM。
T37248	Pantothenate Kinase Inhibitor
	Pantothenate Kinase Inhibitor (PANKi) is a reversible inhibitor of pantothenate kinase (PanK; IC50s = 70, 92, and 25 nM for PanK1β, PanK2, and PanK3, respectively), the rate-limiting enzyme in the synthesis of coenzyme A .1It binds to the ATP-PanK3 complex with an apparent binding constant of 300 nM and exhibits mixed-type inhibition with respect to ATP and pantothenate. PANKi inhibits CoA biosynthesis in C3A cells (IC50= 0.9 μM) with no effect on cell viability when used at concentrations up to...
T72859	11β-HSD1-IN-10
	11β-HSD1-IN-10 (化合物 c3a) 是一种针对11β-HSD1的有效抑制剂，具有对人IC50值为1.8 µM。可应用于肥胖、高血糖和认知障碍研究。

化合物

C3a Receptor Agonist

Cat.No: T38287

Synonym: C3a receptor agonist 1,C3a受体激动剂,Complement 3a Receptor Agonist

Target: Complement System

C3a 70-77 acetate

Cat.No: T7497L1

Synonym: C3a 70-77 acetate (63555-63-5 Free base)

Target: Others

C3a 70-77 2TFA(63555-63-5(free base))

Cat.No: T7497L

Synonym: Complement 3a (70-77)

Target: Complement System

Cat.No: T7497

Synonym: Complement 3a (70-77),C3a 70-77

Target: Complement System

C3a (70-77) TFA (63555-63-5 free base)

Cat.No: TP1193

Synonym: C3a (70-77) TFA,Complement 3a (70-77) (TFA)

C3a (70-77) (TFA)

Cat.No: T75966

Cat.No: T9316

Synonym: 5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride

Target: Complement System

SB290157 trifluoroacetate

Cat.No: T12851

Target: Complement System

Pantothenate Kinase Inhibitor

Cat.No: T37248

11β-HSD1-IN-10

Cat.No: T72859

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00416	Complement C3a Protein, Mouse, Recombinant C3a,Complement Component C3a,Anaphylatoxin	Mouse	E. coli
	Complement C3a Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9 KDa and the accession number is P01027.
TMPJ-00417	Complement C3a Protein, Human, Recombinant Anaphylatoxin,C3a,Complement Component C3a	Human	E. coli
	Complement C3a Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13 KDa and the accession number is P01024.
TMPY-05731	Complement C3 Protein, Human, Recombinant (His) HEL-S-62p,CPAMD1,ARMD9,C3b,ASP,C3a,AHUS5,complement...	Human	HEK293 Cells
	Complement C3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 186.43 kDa and the accession number is P01024.
TMPY-02893	NT5C3A/NT5C3 Protein, Human, Recombinant P5N1,P5N-1,hUMP1,NT5C3,cN-III,PSN1,UMPH1,UMPH,POMP,5'-nucleo...	Human	E. coli
	NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. NT5C3A expression required both an intronic IFN-stimulated response element and the IFN-stimulated transcription factor IRF1. Overexpression of NT5C3A, but...
TMPY-05250	CLEC3A Protein, Mouse, Recombinant (His) C-type lectin domain family 3, member A,Gm796,1110019O10Rik,...	Mouse	Baculovirus Insect Cells
	C-type lectin domain family 3 member A (CLEC3A) is a poorly characterized protein belonging to the superfamily of C-type lectins. Elevated CLEC3A expression may correlate with breast IDC metastatic potential and indicated a poor prognosis in breast IDC. CLEC3A knockdown inhibited BC cell growth and metastasis might be through suppressing PI3K/AKT signaling activity. That CLEC3A is a promising therapeutic target for BC in the future. Matrilysin (MMP-7) plays important roles in tumor progression. ...
TMPH-01235	APOBEC3A Protein, Human, Recombinant (His & SUMO) A3A,APOBEC3A,DNA dC->dU-editing enzyme APOBEC-3A,Ph...	Human	E. coli
	DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a rol...
TMPY-03340	MAP1LC3A Protein, Human, Recombinant (His) LC3,ATG8E,microtubule-associated protein 1 light chain 3 alp...	Human	E. coli
	LC3A, also known as MAP1LC3A, is one of the light chain subunits that function together with both MAP1A and/or MAP1B. MAP1A and MAP1B are microtubule-associated proteins that mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. As a light chain subunit, MAP1LC3A has an important part in neuronal development and in maintaining the balance between neuronal plasticity and r...

重组蛋白

Complement C3a Protein, Mouse, Recombinant

Cat.No: TMPJ-00416

Species: Mouse

Expression System: E. coli

Complement C3a Protein, Human, Recombinant

Cat.No: TMPJ-00417

Species: Human

Expression System: E. coli

Complement C3 Protein, Human, Recombinant (His)

Cat.No: TMPY-05731

Species: Human

Expression System: HEK293 Cells

NT5C3A/NT5C3 Protein, Human, Recombinant

Cat.No: TMPY-02893

Species: Human

Expression System: E. coli

CLEC3A Protein, Mouse, Recombinant (His)

Cat.No: TMPY-05250

Species: Mouse

Expression System: Baculovirus Insect Cells

APOBEC3A Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01235

Species: Human

Expression System: E. coli

MAP1LC3A Protein, Human, Recombinant (His)

Cat.No: TMPY-03340

Species: Human

Expression System: E. coli

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