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3

抑制剂 & 化合物

2

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Cat. No. Product Name Target Signaling Pathways
T9028 STING-IN-2

C-170

STING Immunology/Inflammation
STING-IN-2 (C-170) 是一种 STING 共价抑制剂,可抑制小鼠 STING (mmSTING) 和人类 STING (hsSTING),可用于自身炎症性疾病的研究。
T24203 Jmv 170

Jmv-170,Jmv170

Jmv 170 is the C-terminal heptapeptide of cholecystokinin. It has partial agonist CCK activity on pancreatic amylase release.
T41003 KG5

Raf; FLT; PDGFR; c-Kit Angiogenesis; MAPK; Tyrosine Kinase/Adaptors
KG5 是 PDGFRβ 和 B-Raf 的双重变构抑制剂,对 PDGFRβ 和 PDGFRα 的 Kd 分别为 520 nM 和 300 nM。 KG5 抑制 FLT3、KIT 和 c-Raf,具有抗癌和抗血管生成活性。

化合物

STING-IN-2
Cat.No: T9028
Synonym: C-170
Target: STING
Jmv 170
Cat.No: T24203
Synonym: Jmv-170,Jmv170
Target:
KG5
Cat.No: T41003
Synonym:
Target: Raf, FLT, PDGFR, c-Kit
Cat. No. Product Name Target Signaling Pathways
TN3428 Aphadilactone C

Others Others
Aphadilactone C shows significant antimalarial activity with the IC50 value of 170 ± 10 nM. It shows potent and selective inhibition against the diacylglycerol O-acyltransferase-1 (DGAT-1) enzyme (IC50 = 0.46 ± 0.09 uM, selectivity index > 217).
T35779 Oosporein

Oosporein is a mycotoxin that has been found inBeauveriaand has diverse biological activities.1,2It is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of 4.23 and 10.43 μM, respectively.3Oosporin induces lethality in day-old cockerels (LD50= 6.12 mg/kg).4It inhibits Na+/K+-, Ca2+-, and Mg2+-ATPase activities by 27, 52, and 100%, respectively, in equine erythrocyte ghosts when used at a concentration of 200 μg/ml.2Oosporein inhibits herpes simplex 1 (HSV-1), ...

天然产物

Aphadilactone C
Cat.No: TN3428
Synonym:
Target: Others
Oosporein
Cat.No: T35779
Synonym:
Target:
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