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Search Results for " bitter "

9

抑制剂 & 化合物

12

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T16949	Sucrose octaacetate	Others	Others
	Sucrose octaacetate 是蔗糖的乙酰化衍生物，具有强烈的苦味，可用作苦味替代品。它可用作食品添加剂，还可用作粘合剂和增塑剂。它也可用作软模板，以合成聚苯胺纳米纤维。它还用于许多农药，杀虫剂和其他有毒产品中，以防止意外中毒。
T40417	Ethylhydrocupreine hydrochloride Optochin hydrochloride,乙氢去甲奎宁盐酸盐；奥普托欣盐酸盐	Antibacterial; Parasite	Microbiology/Virology
	Ethylhydrocupreine hydrochloride (Optochin hydrochloride) 是奎宁的一种衍生物，具有抗菌作用，可抑制肺炎链球菌的活性。Ethylhydrocupreine hydrochloride 具有抗疟活性，对 Plasmodium falciparum 的IC50为 25.75 nM。Ethylhydrocupreine hydrochloride 是Gallus gallus2 受体 (ggTas2r1，ggTas2r2和ggTas2r7) 激动剂。
T77989	Nα,Nα-Bis(carboxymethyl)-L-lysine
	Nα,Nα-Bis(carboxymethyl)-L-lysine作为bitter taste receptor 4的一种竞争性抑制剂，其IC50值为59 nM，适用于苦受体相关领域的科学研究。
T82315	GIV3727
	GIV3727 是 hTAS2R 苦味受体的拮抗剂，能够抑制糖精与安赛蜜对 hTAS2R31 的活化作用，有效改善食品、饮料和药品的苦味特性。
T72009	N-Phenylthiourea
	N-Phenylthiourea is a tyrosinase inhibitor and building block. It increases the susceptibility of SK-MEL-188 melanoma cells in melanogenesis-inducing conditions to γ-radiation-induced cytotoxicity when used at a concentration of 0.01 μM. N-Phenylthiourea has been used as a precursor in the synthesis of compounds with antibacterial and antifungal activities. It has also been used as a genetic marker for taste because only some people detect it as a bitter taste.
T36889	Methyl alpha-eleostearate
	Methyl alpha-eleostearate (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. α-ESA is metabolized and converted to conjugated linoleic acid (9Z,11E-CLA) in rats. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, α-ESA induced apoptosis through up-regulation of GADD45, p53, and PPARγ. In DLD-1 cells supple...
T36698	9(Z),11(E),13(E)-Octadecatrienoic Acid
	9(Z),11(E),13(E)-Octadecatrienoic Acid (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. α-ESA is metabolized and converted to conjugated linoleic acid (9Z,11E-CLA) in rats. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, α-ESA induced apoptosis through up-regulation of GADD45, p53, and PPARγ. In DLD-1...
T37476	Cyclo(L-Phe-L-Val)
	Cyclo(L-Phe-L-Val) is a metabolite of the sponge bacterium Pseudoalteromonas sp. NJ6-3-1 that can autoinduce production of antibacterial substances active against S. aureus when co-cultured at a low cell density. It induces neurite outgrowth and branching of chick cortical neurons in vitro when used at concentrations of 16 and 32 μM. It increases phosphorylation of the PI3K substrate Akt, and neurite outgrowth induced by cyclo(L-Phe-L-Val) can be blocked by the PI3K inhibitor LY294002 . Cyclo(L-...
T36888	9(Z),11(E),13(E)-Octadecatrienoic Acid ethyl ester
	9(Z),11(E),13(E)-Octadecatrienoic Acid ethyl ester (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. α-ESA is metabolized and converted to conjugated linoleic acid (9Z,11E-CLA) in rats. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, α-ESA induced apoptosis through up-regulation of GADD45, p53, and PPA...

化合物

Sucrose octaacetate

Cat.No: T16949

Target: Others

Ethylhydrocupreine hydrochloride

Cat.No: T40417

Synonym: Optochin hydrochloride,乙氢去甲奎宁盐酸盐；奥普托欣盐酸盐

Target: Antibacterial, Parasite

Nα,Nα-Bis(carboxymethyl)-L-lysine

Cat.No: T77989

Cat.No: T82315

N-Phenylthiourea

Cat.No: T72009

Methyl alpha-eleostearate

Cat.No: T36889

9(Z),11(E),13(E)-Octadecatrienoic Acid

Cat.No: T36698

Cyclo(L-Phe-L-Val)

Cat.No: T37476

9(Z),11(E),13(E)-Octadecatrienoic Acid ethyl ester

Cat.No: T36888

Cat. No.	Product Name	Target	Signaling Pathways
TN3543	Bruceoside A
	Bruceoside A 是可从鸦胆子分离得到的苦木苷，具有抗癌和肿瘤活性，可用于研究白血病。
TN1740	Homoeriodictyol 高胜草酚,高圣草酚	5-HT Receptor; transporter; Sodium Channel; Drug Metabolite	GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Homoeriodictyol 是 Eriocitrin 的代谢物，属于黄酮类。Eriocitrin 是强效抗氧化剂。
TN1056	Mogroside IIe	IL Receptor	Immunology/Inflammation
	Mogroside IIe 是一种天然来源的三萜糖苷，作为非糖类甜味剂，Mogroside 比蔗糖更甜。Mogroside 具有抗氧化，抗糖尿病和抗癌活性。
TN1943	Momordicoside G	Others	Others
	Momordicosides K and L, the main bitter taste triterpene glycosides in Bitter melon; and bitter melon has been reported to have hypoglycemic, anti atherogenic and anti HIV activities.
TN5176	Trifloroside	Others	Others
	Trifloroside is a bitter iridoid glycoside.
TN3796	Dehydrobruceantinol	Others	Others
	Dehydrobruceantinol shows bitter taste and has antileukemic activity.
T32575	Lascivol
	Lascivol is a bitter substance derived from Tricholoma lascivum.
TN4135	Glaucin B	Others	Others
	Glaucin B is a new bitter limonoid.
T80696	β-Acids colupulone
	β-Acids colupulone为苦味化合物，可从啤酒花中提取分离。
TN4349	Jasminin	Others	Others
	Jasminin 是一种苦味天然化合物，属于黄酮类化合物，存在于各种植物中，包括茉莉花，并已被证明具有抗炎、抗氧化和抗肿瘤活性。
T38417	Kushenol O
	Kushenol O 是一种天然化合物，属于黄酮类。它可从苦参中分离得到。
TN4469	Lyoniresinol
	Lyoniresinol 是一种从 Tarenna attenuata 分离出来的木质素，具有清除自由基的活性（IC50为82.4μM）和 DPPH 的抗氧化活性，显示出抗黑色素生成活性。Lyoniresinol 有强烈的苦味，而其对映体(-)-Lyoniresinol 是无味的。

天然产物

Cat.No: TN3543

Homoeriodictyol

Cat.No: TN1740

Synonym: 高胜草酚,高圣草酚

Target: 5-HT Receptor, transporter, Sodium Channel, Drug Metabolite

Cat.No: TN1056

Target: IL Receptor

Momordicoside G

Cat.No: TN1943

Target: Others

Cat.No: TN5176

Target: Others

Dehydrobruceantinol

Cat.No: TN3796

Target: Others

Cat.No: T32575

Cat.No: TN4135

Target: Others

β-Acids colupulone

Cat.No: T80696

Cat.No: TN4349

Target: Others

Cat.No: T38417

Cat.No: TN4469

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