Cat. No. | Product Name | Target | Signaling Pathways |
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T39823 |
Apelin-12
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Apelin-12 is a highly potent C-terminal fragment of a polypeptide that exhibits a strong affinity towards the orphan receptor APJ. It plays a role in maintaining body fluid balance and regulating feeding control in the central nervous system. Additionally, Apelin-12 functions as an inhibitor of HIV-1 entry through the APJ receptor and demonstrates neuroprotective properties. | |||
T39823L |
Apelin-12 acetate
Apelin-12 acetate (229961-08-4 Free base) |
Apelin receptor; p38 MAPK; JNK | GPCR/G Protein; MAPK |
Apelin-12 acetate 对 APJ 受体具有高亲和力。 Apelin-12 acetate 抑制凋亡相关 MAPKs 家族的 JNK 和 p38 MAPK 信号通路,从而为神经元提供保护。 |