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Cat. No.	Product Name	Target	Signaling Pathways
T0863	Idoxuridine IDU,碘苷,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid	Antifection; HSV	Microbiology/Virology
	Idoxuridine (Dendrid) 是一种抑制病毒 DNA 合成的脱氧尿苷类似物，用作抗病毒剂。
T38239	2'-Deoxy-2'-fluorouridine
	2'-Deoxy-2'-fluorouridine 是合成抗流感病毒试剂的中间体。
T5388	2,5-PYRIDINEDICARBOXYLIC ACID	Others	Others
	2,5-PYRIDINEDICARBOXYLIC ACID 用于制备新的衍生物作为抗病毒剂。
T1649	Tenofovir 替诺福韦,泰诺福韦,PMPA,TDF,GS 1278	HBV; HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Tenofovir (GS 1278) 是一种核苷酸逆转录酶抑制剂，可研究 HIV 和慢性乙型肝炎。
T50012	4-(3-chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one	Others	Others
	4-(3-chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one 已被用作合成多种生物活性化合物的起始材料，包括抗真菌剂、抗病毒剂和抗炎剂。
T3335	Darunavir Ethanolate 地瑞那韦乙醇盐,UIC 94017,Darunavir Ethanolate,TMC114,达芦那韦乙醇	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Darunavir Ethanolate (UIC 94017) 是一种HIV 蛋白酶抑制剂，可以用于 HIV/AIDS 的相关研究。对野生型 HIV-1 蛋白酶的Ki 值为1 nM。
T2324	Darunavir 地瑞那韦,达芦那韦,TMC114	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Darunavir (TMC114) 是一种 HIV 蛋白酶抑制剂，用于治疗艾滋病和 HIV 感染。由于单独使用时会出现抗病毒药物耐药性，因此与其他抗 HIV 药物联合使用。
T1786	Daclatasvir dihydrochloride BMS-790052 dihydrochloride,盐酸达拉他韦	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) 是有机阴离子转运多肽 1B(OATP1B) 和 OATP1B3抑制剂，IC50分别为 1.5 µM 和 3.27 µM。它也具有口服活性的 HCV NS5A 蛋白抑制剂，多种 HCV 复制子基因型的 EC50范围为 9-146 pM。
T50059	6-ethenylquinoline	Others	Others
	6-ethenylquinoline 是一种结构独特的芳香杂环化合物，是生产其他芳香族化合物的重要中间体，并被用作合成各种药物的起始材料，包括抗真菌剂、抗寄生虫剂和抗病毒剂。它已被证明是多种参与药物代谢的酶的抑制剂，包括细胞色素P450、醛氧化酶和黄嘌呤氧化酶等。
T40320	Antiviral agent 5
	Antiviral agent 5 is a crucial intermediate utilized in the development of antiviral agents that specifically target 3C and 3CL proteases, which includes the SARS-CoV-2 M pro enzyme.
T23585	5-Et-ddU ddEtUrd,D2EtU,5-Ethyl-2',3'-dideoxyuridine
	5-Et-ddU, Structure-activity relationships of pyrimidine nucleosides as antiviral agents for human immunodeficiency virus type 1 in peripheral blood mononuclear cells.
T38292	4-(N-Boc-amino)piperidine
	4-(N-Boc-amino)piperidine is an organic building block.1,2It has been used in the synthesis of aminopiperidine antiviral chemokine (C-C motif) receptor 5 (CCR5) antagonists and antibacterial agents. 1.Burrows, J.N., Cumming, J.G., Fillery, S.M., et al.Modulators of the human CCR5 receptor. Part 1: Discovery and initial SAR of 1-(3,3-diphenylpropyl)-piperidinyl amides and ureasBioorg. Med. Chem. Lett.15(1)25-28(2005) 2.Reck, F., Alm, R., Brassil, P., et al.Novel N-linked aminopiperidine inhibitor...
T40358	Ensitrelvir fumarate S-217622 fumarate
	Ensitrelvir (S-217622) fumarate is a novel orally active inhibitor, targeting the SARS-CoV-2 3CL protease (IC50 = 13 nM). It demonstrates non-covalent and non-peptidic characteristics. This compound represents a pioneering advancement in the development of effective antiviral agents against the SARS-CoV-2 virus.
T71275	CID16725315
	Thiocarbazate, also known as CID16725315, is an inhibitor of human cathepsin L. Inhibition of cathepsin L thus holds promise for therapeutic intervention for both SARS-CoV and Ebola virus infection. With respect to the development of antiviral agents, inhibitors of human cathepsin L are not subject to resistance because of rapid mutations of the viral genome. Cathepsin L is therefore an attractive target for drug development.
T35439	(E)-5-(2-Bromovinyl)uracil
	(E)-5-(2-Bromovinyl)uracil (BVU) is a pyrimidine base and an inactive metabolite of the antiviral agents sorivudine and (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) that may be regenerated to BVDU in vivo. BVU irreversibly inactivates dihydropyrimidine dehydrogenase (DPD) in an NADPH-dependent manner. It enhances the efficacy of the chemotherapeutic agent and DPD substrate 5-fluorouracil in a P388 murine leukemia model when administered at a dose of 200 μmol/kg, increasing survival time.
T74578	3'-DMTr-dG(iBu)
	3'-DMTr-dG(iBu)是一种应用于核酸合成的核苷，专用于合成用于研究乙型肝炎病毒(HBV)、丁型肝炎病毒(HDV)感染治疗的抗病毒剂，以及开发针对阿尔茨海默病和其他tau蛋白病治疗的寡核苷酸。
T70846	Deleobuvir sodium
	Deleobuvir sodium is the salt form of Deleobuvir, also known as BI207127, a non-nucleoside hepatitis C virus NS5B polymerase inhibitor for the treatment of hepatitis C. Deleobuvir was tested in combination regimens with pegylated interferon and ribavirin, and in interferon-free regimens with other direct-acting antiviral agents including faldaprevir. Deleobuvir showed that a triple combination of deleobuvir, faldaprevir, and ribavirin performed well in HCV genotype 1b patients. Efficacy fell b...
T36174	Methyl 3,4-Dihydroxyphenylacetate
	Methyl 3,4-dihydroxyphenylacetate is a polyphenol that has been found inI. aquifoliumseeds and has antioxidant and antiviral activities.1,2It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50= 0.0025 mg/ml).1Methyl 3,4-dihydroxyphenylacetate (0.01 μg/ml) inhibits enterovirus 71 replication in rhabdomyosarcoma cells.2 1.Nahar, L., Russell, W.R., Middleton, M., et al.Antioxidant phenylacetic acid derivatives from the seeds of Ilex aquifoliumActa Pharm.55(2)187-193(2005) 2...
T38297	Ribavirin-13C5 Ribavirin-13C5
	Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to an active triphosphate form that induces viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 μg/ml).3Ribavirin also reduces replication of severe acute respiratory syndrome coro...

化合物

Cat.No: T0863

Synonym: IDU,碘苷,SKF 14287,5-Iodo-2′-deoxyuridine,NSC 39661,5-IUdR,Dendrid

Target: Antifection, HSV

2'-Deoxy-2'-fluorouridine

Cat.No: T38239

2,5-PYRIDINEDICARBOXYLIC ACID

Cat.No: T5388

Target: Others

Cat.No: T1649

Synonym: 替诺福韦,泰诺福韦,PMPA,TDF,GS 1278

Target: HBV, HIV Protease, Reverse Transcriptase

4-(3-chlorophenyl)-2,3-dihydro-1,3-thiazol-2-one

Cat.No: T50012

Target: Others

Darunavir Ethanolate

Cat.No: T3335

Synonym: 地瑞那韦乙醇盐,UIC 94017,Darunavir Ethanolate,TMC114,达芦那韦乙醇

Target: HIV Protease

Cat.No: T2324

Synonym: 地瑞那韦,达芦那韦,TMC114

Target: HIV Protease

Daclatasvir dihydrochloride

Cat.No: T1786

Synonym: BMS-790052 dihydrochloride,盐酸达拉他韦

Target: HCV Protease

6-ethenylquinoline

Cat.No: T50059

Target: Others

Antiviral agent 5

Cat.No: T40320

Cat.No: T23585

Synonym: ddEtUrd,D2EtU,5-Ethyl-2',3'-dideoxyuridine

4-(N-Boc-amino)piperidine

Cat.No: T38292

Ensitrelvir fumarate

Cat.No: T40358

Synonym: S-217622 fumarate

Cat.No: T71275

(E)-5-(2-Bromovinyl)uracil

Cat.No: T35439

3'-DMTr-dG(iBu)

Cat.No: T74578

Deleobuvir sodium

Cat.No: T70846

Methyl 3,4-Dihydroxyphenylacetate

Cat.No: T36174

Cat.No: T38297

Synonym: Ribavirin-13C5

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