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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T70399 TTC-352

TTC-352 is an orally bioavailable selective human estrogen receptor alpha (ERalpha; ESR1; ERa) partial agonist (ShERPA), with potential antineoplastic activity. Upon administration, TTC-352 mimics the naturally-occurring 17beta-estradiol (E2) and targets and binds to ERa located in the nucleus. This causes translocation of ERa to extranuclear sites. Nuclear export of ERa prevents normal ER-mediated signaling and inhibits proliferation of ER-positive tumor cells.

化合物

TTC-352
Cat.No: T70399
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T3378 Alpha-Estradiol

α-雌二醇,Alfatradiol,雌二醇,17α-Estradiol,Epiestrol,Epiestradiol

Estrogen/progestogen Receptor; Reductase; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Alpha-Estradiol (Epiestradiol) 是一种雌性激素,可抑制5α-reductase,在雄原性脱发的研究中有潜力。
T1424 Ethynyl estradiol

乙炔基雌二醇,17α-Ethynylestradiol,Ethinyl Estradiol,炔雌醇

Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Ethynyl estradio 是一种高效的生物活性雌激素。
T1571 Estriol

NSC-12169,Oestriol,雌三醇

Estrogen Receptor/ERR; Estrogen/progestogen Receptor; MRP; Endogenous Metabolite Endocrinology/Hormones; Immunology/Inflammation; Metabolism
Estriol (Oestriol) 是G 蛋白偶联雌激素受体拮抗剂,能够作用于雌激素受体阴性乳腺癌细胞。

天然产物

Alpha-Estradiol
Cat.No: T3378
Synonym: α-雌二醇,Alfatradiol,雌二醇,17α-Estradiol,Epiestrol,Epiestradiol
Target: Estrogen/progestogen Receptor, Reductase, Endogenous Metabolite
Ethynyl estradiol
Cat.No: T1424
Synonym: 乙炔基雌二醇,17α-Ethynylestradiol,Ethinyl Estradiol,炔雌醇
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite
Estriol
Cat.No: T1571
Synonym: NSC-12169,Oestriol,雌三醇
Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, MRP, Endogenous Metabolite
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