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Cat. No. | Product Name | Target | Signaling Pathways |
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T70399 |
TTC-352
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TTC-352 is an orally bioavailable selective human estrogen receptor alpha (ERalpha; ESR1; ERa) partial agonist (ShERPA), with potential antineoplastic activity. Upon administration, TTC-352 mimics the naturally-occurring 17beta-estradiol (E2) and targets and binds to ERa located in the nucleus. This causes translocation of ERa to extranuclear sites. Nuclear export of ERa prevents normal ER-mediated signaling and inhibits proliferation of ER-positive tumor cells. |
Cat. No. | Product Name | Target | Signaling Pathways |
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T3378 |
Alpha-Estradiol
α-雌二醇,Alfatradiol,雌二醇,17α-Estradiol,Epiestrol,Epiestradiol |
Estrogen/progestogen Receptor; Reductase; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Alpha-Estradiol (Epiestradiol) 是一种雌性激素,可抑制5α-reductase,在雄原性脱发的研究中有潜力。 | |||
T1424 |
Ethynyl estradiol
乙炔基雌二醇,17α-Ethynylestradiol,Ethinyl Estradiol,炔雌醇 |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Ethynyl estradio 是一种高效的生物活性雌激素。 | |||
T1571 |
Estriol
NSC-12169,Oestriol,雌三醇 |
Estrogen Receptor/ERR; Estrogen/progestogen Receptor; MRP; Endogenous Metabolite | Endocrinology/Hormones; Immunology/Inflammation; Metabolism |
Estriol (Oestriol) 是G 蛋白偶联雌激素受体拮抗剂,能够作用于雌激素受体阴性乳腺癌细胞。 |