Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T21151 |
AT-9283 L-lactate
AT-9283,AT 9283,AT9283 |
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AT-9283 L-lactate is an inhibitor of aurora kinase. | |||
T26675 |
AT-9283 HCl
AT-9283,AT-9283 hydrochloride,AT9283,AT 9283 |
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AT-9283, a multi-targeted kinase inhibitor, is used potentially for the treatment of multiple myeloma. | |||
T3068 |
AT9283
J-504568 |
Apoptosis; FLT; JAK; Bcr-Abl; Aurora Kinase; Autophagy | Angiogenesis; Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors |
AT9283 (J-504568) 是一种多靶点激酶抑制剂,抑制多种实体瘤在体内外的生长和存活,有效抑制Aurora A/B,JAK2/3,Abl (T315I),和Flt3,IC50值范围为 1-30 nM。 |