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Search Results for " ark "

Targets Recommended: Apoptosis Others AMPK

14

抑制剂 & 化合物

1

天然产物

1

化合物库

17

重组蛋白

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Cat. No.	Product Name
L9830	抗帕金森病化合物库		857 compounds
	857 种帕金森病相关的化合物集合，可用于高通量和高内涵筛选；

化合物库

抗帕金森病化合物库

Cat.No: L9830

Compounds: 857

Cat. No.	Product Name	Target	Signaling Pathways
T11947	MARK4 inhibitor 1	Apoptosis; Others; AMPK	Apoptosis; Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling
	MARK4 inhibitor 1 是一种MARK4的抑制剂，IC50值为1.54 μM。它抑制癌细胞增殖、转移，诱导凋亡。
T33884	Parkeol
	Parkeol is the triterpene precursor of saponins in sea cucmbers.
T33885	Parkeyl acetate
	Parkeyl acetate is a bioactive chemical.
T81860	MARK4 inhibitor 4
	MARK4 inhibitor 4，作为一种MARK4抑制剂，具有IC50为1.49 μM。该化合物主要用于癌症和牛头病变相关的研究领域。
T11946	MARK-IN-2	Others	Others
	MARK-IN-2 is a potent microtubule affinity regulating kinase (MARK) inhibitor,(IC50:5 nM).
TP1841	MARK Substrate
	MARK Substrate is a MARK substrate peptide.
T11945	MARK-IN-1	Others	Others
	MARK-IN-1 is a potent microtubule affinity regulating kinase (MARK) inhibitor, (IC50<0.25 nM).
T33408	MitoMark Green I
	MitoMark Green I is a green fluorescent mitochondrial stain [λmax ~ 490/516 nm].
T30474	Bismark Brown Y AI3 52758,AI352758,AI3-52758
	Bismark Brown Y is a brown dye.
T79232	MARK4 inhibitor 2	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	MARK4 inhibitor 2作为MARK4的高效抑制剂，展现出对微管亲和调节激酶 4 (MARK4) 的Km值为6.3×10^7，及IC50为0.82 μM的特异性。它能够抑制癌细胞生长，适用于癌症的科学研究。
T81861	MARK4 inhibitor 3
	MAPK4 inhibitor 3 (compound 23b)为一种抑制MAPK4的化合物，IC50值达1.01 μM。它能有效抑制癌细胞增殖，并可应用于癌症及神经退行性疾病的相关研究。
T32571	Larkspur alkaloid Bicoloridine
	Larkspur alkaloid is a bioactive chemical.
T62251	MARK-IN-4
	MARK-IN-4 是一种有效的微管亲和调节激酶 (MARK) 抑制剂 (IC50: 1 nM)。抑制 MARK 是一种潜在的、有吸引力的方法用于阻止阿尔茨海默病中神经纤维缠结病变。
T33409	MitoMark Red I
	MitoMark Red I is a far red fluorescent mitochondrial stain (λmax ~ 594/608 nm).

化合物

MARK4 inhibitor 1

Cat.No: T11947

Target: Apoptosis, Others, AMPK

Cat.No: T33884

Parkeyl acetate

Cat.No: T33885

MARK4 inhibitor 4

Cat.No: T81860

Cat.No: T11946

Target: Others

Cat.No: TP1841

Cat.No: T11945

Target: Others

MitoMark Green I

Cat.No: T33408

Bismark Brown Y

Cat.No: T30474

Synonym: AI3 52758,AI352758,AI3-52758

MARK4 inhibitor 2

Cat.No: T79232

Target: AMPK

MARK4 inhibitor 3

Cat.No: T81861

Larkspur alkaloid

Cat.No: T32571

Synonym: Bicoloridine

Cat.No: T62251

Cat.No: T33409

Cat. No.	Product Name	Target	Signaling Pathways
T81859	Markogenin
	Markogenin为一Yucca shidgera所源甾类化合物。

天然产物

Cat.No: T81859

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01601	AXL Protein, Human, Recombinant (His) UFO,ARK,JTK11,AXL receptor tyrosine kinase,Tyro7	Human	HEK293 Cells
	AXL Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.5 kDa and the accession number is AAB20305.1.
TMPY-01021	AXL Protein, Mouse, Recombinant (His & hFc) AI323647,AXL receptor tyrosine kinase,Tyro7,Ufo,Ark	Mouse	HEK293 Cells
	AXL Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 74.5 kDa and the accession number is Q00993.
TMPY-06478	AXL Protein, Human, Recombinant (mFc) UFO,JTK11,ARK,Tyro7,AXL receptor tyrosine kinase	Human	HEK293 Cells
	AXL Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 72.11 kDa and the accession number is AAH32229.1.
TMPY-01364	AXL Protein, Mouse, Recombinant (His) Ark,AXL receptor tyrosine kinase,Ufo,Tyro7,AI323647	Mouse	HEK293 Cells
	AXL Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.8 kDa and the accession number is Q00993.
TMPK-00408	AXL Protein, Human, Recombinant (His & Avi), Biotinylated AXL oncogene,EC 2.7.10.1,AI323647,Axl,JTK11,ARK,EC ...	Human	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein, Human, Recombinant (His & Avi), Bio...
TMPK-00410	AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated ARK,EC 2.7.10.1,EC 2.7.10,Axl,JTK11,AXL oncogene,UF...	Human	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein (Primary Amine Labeling), Human, Rec...
TMPK-00407	AXL Protein, Human, Recombinant (His & Avi) AXL oncogene,Axl,EC 2.7.10.1,Tyro7,UFO,ARK,EC 2.7.1...	Human	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein, Human, Recombinant (His & Avi) is e...
TMPK-00472	AXL Protein, Cynomolgus, Recombinant (His) Tyro7,JTK11,AI323647,AXL oncogene,EC 2.7.10.1,EC 2.7.10,UFO,...	Cynomolgus	HEK293 Cells
	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein, Cynomolgus, Recombinant (His) is ex...
TMPH-02461	pylS Protein, Methanosarcina barkeri, Recombinant (His)	Methanosarcina barkeri	E. coli
	Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG. pylS Protein, Methanosarcina barkeri, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 51.8 kDa and the accession number is Q46E77.
TMPY-04771	CARKL Protein, Human, Recombinant (His & GST) SHK,CARKL,sedoheptulokinase	Human	Baculovirus Insect Cells
	CARKL, also known as SHPK, is a nonprotein kinase of glucose metabolism. CARKL has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. CARKL catalyzes an orphan reaction in the pentose phosphate pathway, refocusing cellular metabolism to a high-redox state upon physiological or artificial downregulation. CARKL-dependent metabolic reprogramming is required for proper M1- and ...
TMPY-05872	Influenza A H1N1 (A/swine/Denmark/12813-1/2004) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H1N1	HEK293 Cells
	Influenza A H1N1 (A/swine/Denmark/12813-1/2004) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is U5JC06.
TMPY-02043	PARK7/DJ-1 Protein, Human, Recombinant (His) DJ1,HEL-S-67p,DJ-1,parkinson protein 7	Human	E. coli
	Parkinson's disease locus DJ-1 (PARK7) is a differentially expressed transcript. DJ-1 plays a physiologic role in protection of erythroid cells from oxidant damage, a function unmasked in the context of oxidative stress. PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress...
TMPY-05928	Influenza A H1N1 (A/swine/Denmark/19216B/1993) Neuraminidase/NA Protein (His) NA Protein	H1N1	HEK293 Cells
	Influenza A H1N1 (A/swine/Denmark/19216B/1993) Neuraminidase/NA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.2 kDa and the accession number is A0A0K0NHY2.
TMPY-00485	Olfactory Marker Protein Protein, Human, Recombinant (His) OMP,olfactory marker protein	Human	E. coli
	OMP (Olfactory Marker Protein) is a Protein Coding gene. OMP is a protein expressed in the mature olfactory and vomeronasal neurons of many vertebrates, such as mammals, amphibians, and bony fishes. Its structure and protein sequence are highly conserved between the mouse, rat, and human. OMP is a ubiquitous, cytoplasmic protein found in mature olfactory receptor neurons of all vertebrates. It participates in the olfactory signal transduction pathway. OMP expression is a hallmark of mature verte...
TMPY-05894	Influenza A H3N2 (A/swine/Denmark/101501-1/2010) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H3N2	HEK293 Cells
	Influenza A H3N2 (A/swine/Denmark/101501-1/2010) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is A0A0C4UU26.
TMPH-00137	IBV (strain Arkansas 99) Nucleoprotein/NP Protein (His)	IBV	HEK293 Cells
	Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. IBV (strain Arkansas 99) Nucleoprotein/NP Protein (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 47.4 kDa and the accession...
TMPJ-01081	Dtk Protein, Human, Recombinant (His) RSE,SKY,DTK,Tyrosine-protein kinase DTK,Tyrosine-protein kin...	Human	HEK293 Cells
	Axl (Ufo, Ark), Dtk (Sky, Tyro3, Rse, Brt) and Mer (human and mouse homologues of chicken cEyk)constitute a new receptor tyrosine kinase subfamily. The extracellular domain of these proteins contain two Ig-like motifs and two fibronectin type III motifs. This characteristic topology is also found in neural cell adhesion molecules and in receptor tyrosine phosphatases. All three receptors bind the vitamin K-dependent protein growth-arrest specific gene 6 (Gas6) which is structurally related to th...

重组蛋白

AXL Protein, Human, Recombinant (His)

Cat.No: TMPY-01601

Species: Human

Expression System: HEK293 Cells

AXL Protein, Mouse, Recombinant (His & hFc)

Cat.No: TMPY-01021

Species: Mouse

Expression System: HEK293 Cells

AXL Protein, Human, Recombinant (mFc)

Cat.No: TMPY-06478

Species: Human

Expression System: HEK293 Cells

AXL Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01364

Species: Mouse

Expression System: HEK293 Cells

AXL Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00408

Species: Human

Expression System: HEK293 Cells

AXL Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated

Cat.No: TMPK-00410

Species: Human

Expression System: HEK293 Cells

AXL Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00407

Species: Human

Expression System: HEK293 Cells

AXL Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00472

Species: Cynomolgus

Expression System: HEK293 Cells

pylS Protein, Methanosarcina barkeri, Recombinant (His)

Cat.No: TMPH-02461

Species: Methanosarcina barkeri

Expression System: E. coli

CARKL Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04771

Species: Human

Expression System: Baculovirus Insect Cells

Influenza A H1N1 (A/swine/Denmark/12813-1/2004) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-05872

Species: H1N1

Expression System: HEK293 Cells

PARK7/DJ-1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02043

Species: Human

Expression System: E. coli

Influenza A H1N1 (A/swine/Denmark/19216B/1993) Neuraminidase/NA Protein (His)

Cat.No: TMPY-05928

Species: H1N1

Expression System: HEK293 Cells

Olfactory Marker Protein Protein, Human, Recombinant (His)

Cat.No: TMPY-00485

Species: Human

Expression System: E. coli

Influenza A H3N2 (A/swine/Denmark/101501-1/2010) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-05894

Species: H3N2

Expression System: HEK293 Cells

IBV (strain Arkansas 99) Nucleoprotein/NP Protein (His)

Cat.No: TMPH-00137

Species: IBV

Expression System: HEK293 Cells

Dtk Protein, Human, Recombinant (His)

Cat.No: TMPJ-01081

Species: Human

Expression System: HEK293 Cells

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