Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00072 |
GITR/TNFRSF18 Protein, Human, Recombinant (His)
AITR,GITR-D,tumor necrosis factor receptor superfam... |
Human | HEK293 |
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases... | |||
TMPK-01260 |
GITR/TNFRSF18 Protein, Cynomolgus, Recombinant (aa 20-156, His)
TNFRSF18,GITR-D,AITR,CD357,GITR |
Cynomolgus | HEK293 |
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. | |||
TMPY-05253 |
GITR/TNFRSF18 Protein, Mouse, Recombinant (mFc)
AITR,tumor necrosis factor receptor superfamily, me... |
Mouse | HEK293 |
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases... | |||
TMPK-00132 |
GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His & Avi), Biotinylated
GITR-D,CD357,AITR,GITR,TNFRSF18 |
Human | HEK293 |
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. | |||
TMPK-01086 |
GITR/TNFRSF18 Protein, Mouse, Recombinant (aa 22-153, His)
TNFRSF18,AITR,GITR-D,CD357,GITR |
Mouse | HEK293 |
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. | |||
TMPK-00133 |
GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His)
GITR-D,AITR,GITR,CD357,TNFRSF18 |
Human | HEK293 |
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. | |||
TMPY-06017 |
GITR/TNFRSF18 Protein, Mouse, Recombinant (His)
Gitr,AITR,tumor necrosis factor receptor superfamil... |
Mouse | HEK293 |
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases... | |||
TMPY-05233 |
GITR/TNFRSF18 Protein, Human, Recombinant (His), Biotinylated
GITR-D,CD357,AITR,GITR,tumor necrosis factor recept... |
Human | HEK293 |
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases... | |||
TMPY-05602 |
GITR/TNFRSF18 Protein, Human, Recombinant (hFc & Avi), Biotinylated
AITR,GITR,tumor necrosis factor receptor superfamil... |
Human | HEK293 |
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases... | |||
TMPY-04265 |
GITR/TNFRSF18 Protein, Human, Recombinant (hFc)
GITR-D,tumor necrosis factor receptor superfamily, member 18... |
Human | HEK293 |
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases... | |||
TMPY-06411 |
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated
CD357,GITR-D,tumor necrosis factor receptor superfamily, mem... |
Human | HEK293 |
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases... | |||
TMPJ-00110 |
GITR/TNFRSF18 Protein, Mouse, Recombinant (hFc & His)
Tnfrsf18,GITR-D,CD357,AITR,Tumor necrosis factor re... |
Mouse | Human Cells |
Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The protein is the receptor for TNFSF18.It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It mediated NF-kappa-B activation via the TRAF2/NIK pathway.It binds to TRAF1, TRAF2, and... | |||
TMPY-05292 |
GITRL Protein, Human, Recombinant (His)
TL6,tumor necrosis factor (ligand) superfamily, member 18,hG... |
Human | Baculovirus-Insect Cells |
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Targ... | |||
TMPY-05163 |
GITRL Protein, Human, Recombinant (mFc)
TL6,GITRL,tumor necrosis factor (ligand) superfamily, member... |
Human | HEK293 |
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Targ... | |||
TMPJ-00432 |
GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)
GITRL,TNFSF18,Activation-inducible TNF-related ligand,AI... |
Cynomolgus | Human Cells |
TNFSF18 is a single-pass type II membrane protein. It is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 cytokine binds to TNFRSF18/AITR/GITR. It regulates T-cell responses, and functions as costimulator and lower the threshold for T-cell activation and T-cell proliferation. It is Important for interactions between activated T-lymphocytes and endothelial cells and Promotes leukocyte adhesion to endothelial cells. TNFSF18 mediates activation ... |