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Search Results for " adam-8 "
Targets Recommended: Apoptosis Phosphatase Gamma-secretase Immunology/Inflammation related

1

抑制剂 & 化合物

12

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T13410 ZLDI-8

Apoptosis; Phosphatase; Gamma-secretase; Immunology/Inflammation related Apoptosis; Immunology/Inflammation; Metabolism; Neuroscience; Proteases/Proteasome; Stem Cells
ZLDI-8 是 Notch 激活/裂解酶 ADAM-17 的抑制剂，可抑制 Notch 蛋白裂解，并降低促存活/抗凋亡和上皮-间质转化相关蛋白的表达。它还是竞争性不可逆酪氨酸磷酸酶抑制剂，以IC50为 5.32 μM 抑制 MHCC97-H 细胞的生长。

化合物

ZLDI-8
Cat.No: T13410
Synonym:
Target: Apoptosis, Phosphatase, Gamma-secretase, Immunology/Inflammation related
Species：
Human (10)
Mouse (1)
Rhesus (1)
Expression System：
HEK293 Cells (10)
E. coli (2)
Tag：
C-His (6)
C-6xHis (1)
C-hFc (1)
His, hFc (1)
N-6xHis (1)
N-8xHis-Flag (1)
Tag Free (1)
Cat. No. Product Name Species Expression System
TMPY-03877 ADAM8/CD156a Protein, Rhesus, Recombinant (His)

ADAM metallopeptidase domain 8

 Rhesus HEK293 Cells
ADAM8/CD156a Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 53.6 kDa and the accession number is XP_002805919.1.
TMPK-00918 ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His)

CD156a,ADAM 8,MGC134985,Adam<...

 Human HEK293 Cells
A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. ADAM8/...
TMPK-00933 ADAM8/CD156a Protein, Mouse, Recombinant (His)

CD156a,MGC134985,ADAM 8,Ms2,A...

 Mouse HEK293 Cells
A Disintegrin And Metalloproteinase (ADAM) proteases constitute a family of multifunctional, membrane-bound proteins with traditional sheddase functions. Their protumorigenic potential has been attributed to both, essential (ADAM10 and ADAM17) and 'dispensable' ADAM proteases (ADAM8, 9, 12, 15, and 19). Of specific interest in this review is the ADAM proteinase ADAM8 that has been identified as a significant player in aggressive malignancies including breast, pancreatic, and brain cancer. ADAM8/...
TMPY-05532 ADAM8/CD156a Protein, Human, Recombinant (His)

CD156,MS2,CD156a,ADAM metallopeptidase domain 8...

 Human HEK293 Cells
ADAM8/CD156a Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71 kDa and the accession number is Q14C66.
TMPY-04123 CEACAM1 Protein, Human, Recombinant (His & hFc)

CEACAM‑1,carcinoembryonic antigen-related cell adhesion mole...

 Human HEK293 Cells
CEACAM1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 71.4 kDa and the accession number is P13688-8.
TMPJ-00808 CD45RA Protein, Human, Recombinant (His)

PTPRC,CD45R,CD45,LCA,protein tyrosine phosphatase, receptor ...

 Human HEK293 Cells
CD45RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-135 KDa and the accession number is P08575-8.
TMPH-01705 Mucin-1/MUC1 Protein, Human, Recombinant (His)

Human E. coli
Mucin-1/MUC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.2 kDa and the accession number is P15941-8.
TMPJ-00828 Tau-F Protein, Human, Recombinant

Neurofibrillary tangle protein,Paired helical filament-tau,M...

 Human E. coli
Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. The tau proteins are the product of alternative splicing from a single gene that in humans is designated MAPT. When tau proteins are def...
TMPY-00717 CEACAM1 Protein, Human, Recombinant (His)

CEACAM‑1,BGP1,BGP,carcinoembryonic antigen-related cell adhe...

 Human HEK293 Cells
CEACAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.8 kDa and the accession number is P13688-8.
TMPY-06707 Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His)

ADMCKD,PEMT,KL-6,ADMCKD1,H23AG,mucin 1, cell surface associa...

 Human HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.49 kDa and the accession number is P15941-8.
TMPJ-01330 CD299 Protein, Human, Recombinant (His & Flag)

DC-SIGNR,L-SIGN,CD299,CD209L,LSIGN,C-type lectin domain fami...

 Human HEK293 Cells
CD299 is also known as DC-SIGNR and CLEC4M, is a type II integral membrane protein. DC-SIGNR exists as a homotetramer, and the tandem repeat domain, also called neck domain, mediates oligermerization. Multiple human DC-SIGN/CD209 splice forms exist, generating both membrane-bound and soluble forms. DC-SIGNR is ragarded as a pathogen-recognition receptor involved in peripheral immune surveillance in liver, and probably mediate the endocytosis of pathogens which are subsequently degraded in lysoso...
TMPY-00668 APP/Protease nexin-II Protein, Human, Recombinant (hFc)

CTFγ,amyloid beta (A4) precursor protein,AAA,ABPP,CVAP,APPI,...

 Human HEK293 Cells
APP/Protease nexin-II Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101 kDa and the accession number is P05067-8.

重组蛋白

ADAM8/CD156a Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-03877
Species: Rhesus
Expression System: HEK293 Cells
ADAM8/CD156a Protein, Human, Recombinant (aa 17-655, His)
Cat.No: TMPK-00918
Species: Human
Expression System: HEK293 Cells
ADAM8/CD156a Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00933
Species: Mouse
Expression System: HEK293 Cells
ADAM8/CD156a Protein, Human, Recombinant (His)
Cat.No: TMPY-05532
Species: Human
Expression System: HEK293 Cells
CEACAM1 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-04123
Species: Human
Expression System: HEK293 Cells
CD45RA Protein, Human, Recombinant (His)
Cat.No: TMPJ-00808
Species: Human
Expression System: HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01705
Species: Human
Expression System: E. coli
Tau-F Protein, Human, Recombinant
Cat.No: TMPJ-00828
Species: Human
Expression System: E. coli
CEACAM1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00717
Species: Human
Expression System: HEK293 Cells
Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-173, His)
Cat.No: TMPY-06707
Species: Human
Expression System: HEK293 Cells
CD299 Protein, Human, Recombinant (His & Flag)
Cat.No: TMPJ-01330
Species: Human
Expression System: HEK293 Cells
APP/Protease nexin-II Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00668
Species: Human
Expression System: HEK293 Cells
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