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Targets Recommended: PDE

6

抑制剂 & 化合物

8

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T36832 PDE4B-IN-2

A 33

PDE Metabolism
PDE4B-IN-2 (A 33) 是一种具有口服活性,选择性 PDE4B 抑制剂,IC50 为 15 nM。PDE4B-IN-2 抑制 PDE4D (IC50=1.7 µM)。PDE4B-IN-2 表现出有效的抗炎作用。
T40950 A3334

A3051, is a robust and orally active inhibitor of CXXC5-DVL with an IC 50 of 63.06 nM. Its applications include research into phenotypes associated with obesity, diabetes, and NASH that are induced by high fat diet (HFD) and methionine-choline deficient diet (MCD).
T68826 A33903

A33903 is a 1,4-benzodiazepine analog that is being studied as a potential inhibitor of respiratory syncytial virus. This molecule was moderately active and demonstrated good pharmacokinetic properties.
T83226 A3373

Phospholipase Metabolism
A3373 是新型 PLD1 和 PLD2 抑制剂,对 PLD1 的 IC50 为 325 nM ,对 PLD2 的 IC50 为 15.15 µM,能够有效抑制 LPS 诱导的免疫反应,并在自身免疫性关节炎、骨脱矿及破骨细胞生成等方面发挥关键作用。
T26480 A331440

A-331440,A331440 free base,A 331440

A331440 is an modulator of L-histidine and histamine H3 receptor.
T22935 LU AA33810

Others Others
LU AA33810 is a neuropeptide Y (NPY) Y5 receptor antagonist.

化合物

PDE4B-IN-2
Cat.No: T36832
Synonym: A 33
Target: PDE
A3334
Cat.No: T40950
Synonym:
Target:
A33903
Cat.No: T68826
Synonym:
Target:
A3373
Cat.No: T83226
Synonym:
Target: Phospholipase
A331440
Cat.No: T26480
Synonym: A-331440,A331440 free base,A 331440
Target:
LU AA33810
Cat.No: T22935
Synonym:
Target: Others
Cat. No. Product Name Species Expression System
TMPY-02012 A33 Protein, Human, Recombinant (His)

glycoprotein A33 (transmembrane),A33

Human HEK293 Cells
A33 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is Q99795-1.
TMPK-01147 GPA33/A33 Protein, Human, Recombinant (His & Avi)

A33,Glycoprotein A33,MGC129986,GPA33

Human HEK293 Cells
GPA33/A33 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.5 kDa and the accession number is Q99795-1.
TMPK-01148 GPA33/A33 Protein, Human, Recombinant (His & Avi), Biotinylated

A33,GPA33,MGC129986,MGC129987,Glycoprotein...

Human HEK293 Cells
GPA33/A33 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.5 kDa and the accession number is Q99795-1.
TMPY-01794 A33 Protein, Mouse, Recombinant (His)

BB116197,2210401D16Rik,2010310L10Rik,glycoprotein A33

Mouse HEK293 Cells
A33 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.4 kDa and the accession number is A0A0R4J209.
TMPY-06574 Vaccinia virus (VACV) (strain Copenhagen) A33R Protein (His)

VACV E. coli
Vaccinia virus (VACV) (strain Copenhagen) A33R Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 15.18 kDa and the accession number is P68616.
TMPH-03662 Vaccinia virus (strain Copenhagen) OPG161 Protein (A33R, E. coli, His)

VACV E. coli
Coordinates the incorporation of A36 into intracellular enveloped virion (IEV) membranes and, subsequently, the production of actin tails. Therefore plays an essential role in efficient cell-to-cell spread of viral particles. Vaccinia virus (strain Copenhagen) OPG161 Protein (A33R, E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 17.8 kDa and the accession number is P68616.
TMPH-03663 Vaccinia virus (strain Copenhagen) OPG161 Protein (A33R, His)

VACV Baculovirus Insect Cells
Coordinates the incorporation of A36 into intracellular enveloped virion (IEV) membranes and, subsequently, the production of actin tails. Therefore plays an essential role in efficient cell-to-cell spread of viral particles. Vaccinia virus (strain Copenhagen) OPG161 Protein (A33R, His) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 18.3 kDa and the accession number is P68616.
TMPY-06584 Monkeypox Virus (MPXV) A33R Protein (His & GST)

MPXV E. coli
Monkeypox Virus (MPXV) A33R Protein (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 44.07 kDa.

重组蛋白

A33 Protein, Human, Recombinant (His)
Cat.No: TMPY-02012
Species: Human
Expression System: HEK293 Cells
GPA33/A33 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-01147
Species: Human
Expression System: HEK293 Cells
GPA33/A33 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-01148
Species: Human
Expression System: HEK293 Cells
A33 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01794
Species: Mouse
Expression System: HEK293 Cells
Vaccinia virus (VACV) (strain Copenhagen) A33R Protein (His)
Cat.No: TMPY-06574
Species: VACV
Expression System: E. coli
Vaccinia virus (strain Copenhagen) OPG161 Protein (A33R, E. coli, His)
Cat.No: TMPH-03662
Species: VACV
Expression System: E. coli
Vaccinia virus (strain Copenhagen) OPG161 Protein (A33R, His)
Cat.No: TMPH-03663
Species: VACV
Expression System: Baculovirus Insect Cells
Monkeypox Virus (MPXV) A33R Protein (His & GST)
Cat.No: TMPY-06584
Species: MPXV
Expression System: E. coli
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