Cat. No. | Product Name | Target | Signaling Pathways |
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T1158L |
Phenoxybenzamine
NSC-37448,A688,NSC 37448,NSC37448,A-688 |
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Phenoxybenzamine is an α-1 adrenergic receptor antagonist. Phenoxybenzamine may exert a neuroprotective effect by reducing neuroinflammation after traumatic brain injury. | |||
T17252 |
SIM-688
SIM688 |
Estrogen/progestogen Receptor; NF-κB | Endocrinology/Hormones; NF-κB |
SIM-688 是一种选择性和口服活性的雌激素受体抑制剂,抑制 NF-κB 转录活性(在 HAECT-1 细胞中 IC50 = 122 nM)。 | |||
T25737 |
Linetastine
TMK 688,TMK-688,TMK688 |
Lipoxygenase; LTR; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience |
Linetastine (TMK-688) 是一种 5-脂氧合酶抑制剂(5-LOX),能抑制白三烯的产生,并能拮抗组胺的作用。Linetastine可用于研究哮喘、动脉粥样硬化和消化性溃疡。 | |||
T65213 |
2-(2-Aminoacetamido)-4-methylpentanoic acid
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2-(2-Aminoacetamido)-4-methylpentanoic acid 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T65213,CAS号为 688-14-2。 | |||
T69649 |
NITD-688
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NITD-688 是一种具有口服活性的登革病毒 (dengue virus)NS4B 蛋白的泛血清型抑制剂。 NITD-688 可用于登革热病毒 (DENV) 的研究。 | |||
T37419 | Zetomipzomib | ||
KZR-616, a first-in-class inhibitor of the immunoproteasome, selectively targets the LMP7 (IC50: 39/57 nM=hLMP7/mLMP7) and LMP2 (IC50: 131/179 nM=hLMP7/mLMP7) subunits of the immunoproteasome. KZR-616 has the potential for the research of multiple autoimmune diseases[1][2]. KZR-616 also inhibits MECL-1 subunit (IC50=623 nM) and constitutive proteasome β5 subunit (IC50=688 nM). KZR-616 maintains LMP7 and LMP2 selective inhibition in MOLT-4 cells. KZR-616 (250 nM) shows a comparable cytokine inhib... |