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Search Results for " 2' deoxycytidine "

25

抑制剂 & 化合物

7

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T7718	5-Fluoro-2'-deoxycytidine 5-氟脱氧胞苷,FdCyd,2'-DEOXY-5-FLUOROCYTIDINE	DNA Methyltransferase	Chromatin/Epigenetic
	5-Fluoro-2'-deoxycytidine (2'-DEOXY-5-FLUOROCYTIDINE) 是一种 DNA 甲基转移酶(DNMT) 抑制剂，是氟嘧啶核苷类似物。它是胸苷酸合酶抑制剂 5-fluoro-2′-dUMP 的肿瘤选择性前药。
T7518	Deoxycytidine triphosphate trisodium salt 2'-脱氧胞苷-5'-三磷酸三钠盐,2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI	Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis; Endogenous Metabolite; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) 是可用于 DNA 合成的核苷三磷酸，可用于实时荧光定量 PCR、cDNA 合成和 DNA 测序。
TNU1205	2’-Deoxy-N4-methylcytidine N(3)-Methyl-2'-deoxycytidine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2’-Deoxy-N4-methylcytidine (N(3)-Methyl-2'-deoxycytidine) 是一种嘌呤核苷类似物，具有潜在的抗肿瘤活性，可用于研究细胞凋亡。
T22494	2'-Deoxycytidine hydrochloride	Others	Others
	2'-Deoxycytidine hydrochloride 可以抑制溴脱氧尿苷 (Brdu) 的生物效应。2'-Deoxycytidine hydrochloride 可用于癌症研究。
T36972	5-O-TBDMS-N4-Benzoyl-2-deoxycytidine 5-O-TBDMS-N4-Benzoyl-2-deoxycytidine
	5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside utilized in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.
T10067	2',5-Difluoro-2'-deoxycytidine	HCV Protease	Microbiology/Virology; Proteases/Proteasome
	2',5-Difluoro-2'-deoxycytidine has potent anti-HCV activity and toxicity to rRNA.
T40783	N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine N4-苯甲酰基-5′-O-(4,4′-二甲氧基三苯基)-2′-脱氧胞苷,5'-O-DMT-N4-Bz-dC
	N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine, also known as 5'-O-DMT-N4-Bz-dC, is a chemical compound utilized in the synthesis of oligodeoxynucleotides that incorporate a 3'-S-phosphorothiolate (3'-PS) linkage. It is valuable in investigating enzyme-catalyzed cleavage mechanisms within DNA.
TNU0230	2’-Azido-2’-deoxycytidine
	Nucleoside Derivatives - Azido-nucleosides, 2’-Modified nucleosides; Drugs and Inhibitors; antiviral agent, DNA synthesis inhibitor; Ribonucleotide reductase inhibitor
TNU0231	2’-Amino-2’-deoxycytidine
	Nucleoside Derivatives - Amino-nucleosides, 2’-Modified nucleosides
TNU0074	2’-Chloro-2’-deoxycytidine
	Nucleoside Derivatives - Halo-nucleosides, 2’-Modified nucleosides
TNU1613	N4-Ethyl-2’-deoxycytidine
	N4-Ethyl-2'-deoxycytidine is a Nucleoside Derivative - N-Methylated alkylated nucleoside.
TNU1463	N4-Acetyl-2’-deoxycytidine
	Nucleoside Derivatives –Other modified nucleosides
T27154	Dexelvucitabine D-D-4FC,DPC-817,RVT,beta-D-D-4FC,DFC	Reverse Transcriptase	Microbiology/Virology
	Dexelvucitabine (RVT) 是一种胞苷类似物，一种口服有活性的核苷逆转录酶抑制剂。它是一种 2'-脱氧胞苷抗逆转录病毒剂。它是一种有效的抗 HIV-1病毒剂，这些病毒聚合酶中含有胸苷类似物和/或 M184V 突变。
TNU1102	5’-O-(4,4’-Dimethoxytrityl)-2’-deoxycytidine
	5'-O-(4,4'-Dimethoxytrityl)-2'-deoxycytidine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open.
T83828	Sp-2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium Sp-dCTP-α-S
	Sp-2'-Deoxycytidine-5'-O-(1-thiotriphosphate) (Sp-dCTP-α-S) 是含硫核苷酸衍生物 dCTP-α-S 的异构体。它抑制解氧核苷酸三磷酸三磷酸水解酶 SAMHD1（Ki = 6.3 µM）。
TNU1464	N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine
	Nucleoside Derivatives –Protectednucleosidesw/NH2/OH open
T67323	5'-O-(Tert-butyldimethylsilyl)-5-iodo-2'-deoxycytidine
	5'-O-(Tert-butyldimethylsilyl)-5-iodo-2'-deoxycytidine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67323，CAS号为 666848-11-9。
T75200	N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-5-methyl-2’-deoxycytidine
	N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-5-methyl-2’-deoxycytidine 是一种具有广泛抗肿瘤活性的嘌呤核苷类似物，主要针对惰性淋巴系统的恶性肿瘤。其抗癌机制涉及抑制DNA合成及诱导细胞凋亡(apoptosis)等作用。
TNU1605	N4-Bz-3’-O-DMTr-2’-deoxycytidine 5’-O-CE-phosphoramidite
	N4-Bz-3'-O-DMTr-2'-deoxycytidine 5'-O-CE-phosphoramidite is a Nucleoside Phosphoramidite.
TNU1299	5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite
	Nucleoside Derivatives - Fluoro-modified nucleosides; 2’-Modified nucleosides; Nucleoside Phosphoramidites
T19152	5-OHdU 5-羟基-2'-脱氧尿苷	Nucleoside Antimetabolite/Analog; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	5-OHdU (5-OHdU) 是 2'-Deoxycytidine 的主要氧化产物，可在体外掺入 DNA。
T50079	2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine	Others	Others
	2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine 可用于开发新的脱氧胞苷激酶（dCK）抑制剂。
T6501	Fludarabine Phosphate NSC 312887 Phosphate,fludara Phosphate,F-ara-A (NSC 312887) Phosphate,F-ara-AMP,磷酸氟达拉滨	Apoptosis; Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Fludarabine Phosphate (NSC 312887 Phosphate) 是一种腺苷和脱氧腺苷类似物，与 dATP 竞争，并入到 DNA，可以抑制 DNA 聚合酶 α、核糖核苷酸还原酶和 DNA 引发酶，从而中断 DNA 合成并抑制肿瘤细胞生长。
TNU1592	5-Aza-3’-deoxycytidine
	5-Aza-3’-deoxycytidine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TNU1592，CAS号为 455951-65-2。
T37983	GM 1489
	GM 1489 is a broad-spectrum inhibitor of matrix metalloproteinases (MMPs) with Ki values of 0.002, 0.1, 0.5, 0.2, and 20 μM for MMP-1, MMP-8, MMP-2, MMP-9, and MMP-3, respectively. It reduces 5-aza-2'-deoxycytidine-induced increases in MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, and MMP-14 expression as well as cell invasion in AsPC-1, BxPC-3, Hs766T, MiaPaCa2, and PANC-1 cancer cells. Topical administration of GM 1489 (100 μg) inhibits increases in ear thickness and epidermal hyperplasia induced by phor...

化合物

5-Fluoro-2'-deoxycytidine

Cat.No: T7718

Synonym: 5-氟脱氧胞苷,FdCyd,2'-DEOXY-5-FLUOROCYTIDINE

Target: DNA Methyltransferase

Deoxycytidine triphosphate trisodium salt

Cat.No: T7518

Synonym: 2'-脱氧胞苷-5'-三磷酸三钠盐,2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI

Target: Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Endogenous Metabolite, Antibiotic

2’-Deoxy-N4-methylcytidine

Cat.No: TNU1205

Synonym: N(3)-Methyl-2'-deoxycytidine

Target: Nucleoside Antimetabolite/Analog

2'-Deoxycytidine hydrochloride

Cat.No: T22494

Target: Others

5-O-TBDMS-N4-Benzoyl-2-deoxycytidine

Cat.No: T36972

Synonym: 5-O-TBDMS-N4-Benzoyl-2-deoxycytidine

2',5-Difluoro-2'-deoxycytidine

Cat.No: T10067

Target: HCV Protease

N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine

Cat.No: T40783

Synonym: N4-苯甲酰基-5′-O-(4,4′-二甲氧基三苯基)-2′-脱氧胞苷,5'-O-DMT-N4-Bz-dC

2’-Azido-2’-deoxycytidine

Cat.No: TNU0230

2’-Amino-2’-deoxycytidine

Cat.No: TNU0231

2’-Chloro-2’-deoxycytidine

Cat.No: TNU0074

N4-Ethyl-2’-deoxycytidine

Cat.No: TNU1613

N4-Acetyl-2’-deoxycytidine

Cat.No: TNU1463

Dexelvucitabine

Cat.No: T27154

Synonym: D-D-4FC,DPC-817,RVT,beta-D-D-4FC,DFC

Target: Reverse Transcriptase

5’-O-(4,4’-Dimethoxytrityl)-2’-deoxycytidine

Cat.No: TNU1102

Sp-2'-Deoxycytidine-5'-O-(1-thiotriphosphate) sodium

Cat.No: T83828

Synonym: Sp-dCTP-α-S

N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-2’-deoxycytidine

Cat.No: TNU1464

5'-O-(Tert-butyldimethylsilyl)-5-iodo-2'-deoxycytidine

Cat.No: T67323

N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-5-methyl-2’-deoxycytidine

Cat.No: T75200

N4-Bz-3’-O-DMTr-2’-deoxycytidine 5’-O-CE-phosphoramidite

Cat.No: TNU1605

5’-O-DMTr-2’,2’-difluoro-dC(Bz)-3’-CED-phosphoramidite

Cat.No: TNU1299

Cat.No: T19152

Synonym: 5-羟基-2'-脱氧尿苷

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

2-({[2-(4-ethoxy-3-methoxyphenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)pyrimidine-4,6-diamine

Cat.No: T50079

Target: Others

Fludarabine Phosphate

Cat.No: T6501

Synonym: NSC 312887 Phosphate,fludara Phosphate,F-ara-A (NSC 312887) Phosphate,F-ara-AMP,磷酸氟达拉滨

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis

5-Aza-3’-deoxycytidine

Cat.No: TNU1592

Cat.No: T37983

Cat. No.	Product Name	Target	Signaling Pathways
T4758	2'-Deoxycytidine Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物	Endogenous Metabolite	Metabolism
	2'-Deoxycytidine (Deoxyribose cytidine) 是由胞嘧啶和脱氧核糖组成的DNA的主要核苷之一。核苷仅由与嘌呤或嘧啶碱相连的戊糖组成，没有磷酸基团。当N1与脱氧核糖的C1连接时，由胞嘧啶和脱氧核糖形成脱氧核苷和核苷酸；脱氧胞苷单磷酸(dCMP)，脱氧胞苷二磷酸(dCDP)，脱氧胞苷三磷酸(dCTP)。CTP是RNA(核糖核酸)中胞苷的来源，脱氧胞苷三磷酸(dCTP)是DNA(脱氧核糖核酸)中脱氧胞苷的来源。
T7961	N4-Benzoyl-2′-deoxycytidine N-苯甲酰-2'-脱氧胞苷	Others	Others
	N4-Benzoyl-2′-deoxycytidine 是天然核苷脱氧胞苷（dC）的合成核苷类似物，是一种DNA 聚合酶的竞争性抑制剂。体外研究表明，它可以抑制病毒、细菌和真核细胞的复制。在动物模型中，它也被证明可以抑制肿瘤细胞的生长。
T40834	5-Hydroxymethyl-2'-deoxycytidine 5hmdC,2'-脱氧-5-(羟甲基)胞啶	PARP	Chromatin/Epigenetic; DNA Damage/DNA Repair
	5-Hydroxymethyl-2'-deoxycytidine 是 DNA 中 5-methyl-2'-deoxycytidine (5-mdC) 的氧化衍生物，引起DNA损伤反应，染色体畸变，复制叉损伤和细胞活力丧失。5-Hydroxymethyl-2’-deoxycytidine 复制叉不稳定性与染色质上聚（ADP-核糖）聚合酶1（PARP1）的存在有关。
T4731	2'-Deoxycytidine-5'-monophosphoric acid dCMP,2'-脱氧胞苷 5'-单磷酸,2'-Deoxycytidine 5'-monophosphate	Others; Endogenous Metabolite	Metabolism; Others
	2'-Deoxycytidine-5'-monophosphoric acid (2'-Deoxycytidine 5'-monophosphate) 被用作尿苷单磷酸(UMP)或胞苷单磷酸(CMP)激酶的底物，形成 dCDP，在磷酸化成 dCTP 后支持 DNA 的生物合成。
T4972	2'-Deoxycytidine-5'-diphosphate trisodium dCDP,2'-脱氧胞苷-5'-二磷酸三钠盐	Endogenous Metabolite	Metabolism
	2'-Deoxycytidine-5'-diphosphate trisodium (dCDP) 是内源性代谢产物的一种。
T7457	5-Methyl-2'-deoxycytidine 5-Methyldeoxycytidine,5-甲基-2'-脱氧胞苷,5MedCyd	DNA Methyltransferase; Endogenous Metabolite	Chromatin/Epigenetic; Metabolism
	5-Methyl-2'-deoxycytidine (5MedCyd) 是嘧啶核苷，当掺入到单链 DNA 中时，可以顺式作用以从头发出信号。
T1508	Decitabine Dacogen,NSC 127716,地西他滨,Deoxycytidine,5-Aza-2'-deoxycytidine	Apoptosis; Nucleoside Antimetabolite/Analog; DNA Methyltransferase	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Decitabine (Deoxycytidine) 是脱氧胞苷类似物，一种 DNA 甲基转移酶抑制剂，具有口服活性。Decitabine 具有抗肿瘤活性和抗代谢活性。Decitabine 诱导细胞周期阻滞和凋亡。

天然产物

2'-Deoxycytidine

Cat.No: T4758

Synonym: Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物

Target: Endogenous Metabolite

N4-Benzoyl-2′-deoxycytidine

Cat.No: T7961

Synonym: N-苯甲酰-2'-脱氧胞苷

Target: Others

5-Hydroxymethyl-2'-deoxycytidine

Cat.No: T40834

Synonym: 5hmdC,2'-脱氧-5-(羟甲基)胞啶

Target: PARP

2'-Deoxycytidine-5'-monophosphoric acid

Cat.No: T4731

Synonym: dCMP,2'-脱氧胞苷 5'-单磷酸,2'-Deoxycytidine 5'-monophosphate

Target: Others, Endogenous Metabolite

2'-Deoxycytidine-5'-diphosphate trisodium

Cat.No: T4972

Synonym: dCDP,2'-脱氧胞苷-5'-二磷酸三钠盐

Target: Endogenous Metabolite

5-Methyl-2'-deoxycytidine

Cat.No: T7457

Synonym: 5-Methyldeoxycytidine,5-甲基-2'-脱氧胞苷,5MedCyd

Target: DNA Methyltransferase, Endogenous Metabolite

Cat.No: T1508

Synonym: Dacogen,NSC 127716,地西他滨,Deoxycytidine,5-Aza-2'-deoxycytidine

Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA Methyltransferase

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