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Cat. No. Product Name Target Signaling Pathways
TN3219 7,8-Didehydrocimigenol

ERK; IκB/IKK; TNF; NF-κB; Akt; PPAR Apoptosis; Cytoskeletal Signaling; DNA Damage/DNA Repair; MAPK; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of TNF-α-activated EC which leads to selective inhibition of VCAM-1 expression.

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7,8-Didehydrocimigenol
Cat.No: TN3219
Synonym:
Target: ERK, IκB/IKK, TNF, NF-κB, Akt, PPAR
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