在血液系统恶性肿瘤中,CD19、BCMA 和 CD22 是最常研究的靶点蛋白。其中CD19是治疗 B 细胞血液癌症的首要靶点。BCMA 和 CD22 都是 B 细胞表面表达的抗原,靶向这两个靶点的细胞疗法可以用于治疗对靶向 CD19 的细胞疗法产生耐药性的 B 细胞血液癌症患者。其他正在研究的相关靶点还有GPRC5D、CLEC12A和 CD7等。
Cat. No. | Product Name / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-05201 | Siglec-2/CD22 Protein, Human, Recombinant
Siglec-2/CD22 Protein, Human, Recombinant
|
Human | HEK293 |
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface... | |||
TMPY-02409 | Siglec-3/CD33 Protein, Cynomolgus, Rhesus, Recombinant (His)
Siglec-3/CD33 Protein, Cynomolgus, Rhesus, Recombinant (His)
|
Cynomolgus,Rhesus | HEK293 |
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and... | |||
TMPY-04649 | ROR1 Protein, Human, Recombinant (His)
ROR1 Protein, Human, Recombinant (His)
|
Human | HEK293 |
ROR1 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 43.4 kDa. Accession number: Q01973 | |||
TMPY-01741 | CD19 Protein, Mouse, Recombinant (His)
CD19 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified... | |||
TMPY-05540 | CD19 Protein, Mouse, Recombinant (His), Biotinylated
CD19 Protein, Mouse, Recombinant (His), Biotinylated
|
Mouse | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified... | |||
TMPY-01949 | CD19 Protein, Human, Recombinant (His)
CD19 Protein, Human, Recombinant (His)
|
Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified... | |||
TMPY-03376 | NKG2D/CD314 Protein, Rhesus, Recombinant (aa 78-216, His)
NKG2D/CD314 Protein, Rhesus, Recombinant (aa 78-216, His)
|
Rhesus | Baculovirus-Insect Cells |
KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked typ... | |||
TMPY-01483 | SLAMF7 Protein, Human, Recombinant (His)
SLAMF7 Protein, Human, Recombinant (His)
|
Human | HEK293 |
SLAM family member 7 (SLAMF7), also known as CRACC, CD319, CD2-like receptor-activating cytotoxic cells, and CS1, is a single-pass type I membrane protein and a ... | |||
TMPY-05427 | CD19 Protein, Human, Recombinant (hFc)
CD19 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified... | |||
TMPY-05530 | CD19 Protein, Cynomolgus/Rhesus, Recombinant (His), Biotinylated
CD19 Protein, Cynomolgus/Rhesus, Recombinant (His), Biotinylated
|
Cynomolgus,Rhesus | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified... | |||
TMPY-05271 | CD20 Protein, Human, Recombinant (TrxA), Biotinylated
CD20 Protein, Human, Recombinant (TrxA), Biotinylated
|
Human | E. coli |
CD20 (membrane-spanning 4-domains, subfamily A, member 1), also known as MS4A1, is a member of the membrane-spanning 4A gene family. Members of this nascent prot... | |||
TMPJ-00147 | FOLR1 Protein, Human, Recombinant (hFc)
FOLR1 Protein, Human, Recombinant (hFc)
|
Human | Human Cells |
Folate receptor alpha(FOLR) belongs to the folate receptor family, and is primarily expressed in tissues of epithelial origin. It is also expressed in kidney, lu... | |||
TMPY-01803 | FOLR1 Protein, Mouse, Recombinant (His)
FOLR1 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transpo... | |||
TMPY-05414 | NKG2D/CD314 Protein, Mouse, Recombinant (hFc)
NKG2D/CD314 Protein, Mouse, Recombinant (hFc)
|
Mouse | Baculovirus-Insect Cells |
KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked typ... | |||
TMPY-05566 | Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)
Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)
|
Human | HEK293 |
CD22 is a member of the immunoglobulin superfamily, SIGLEC family of lectins. It is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface... | |||
TMPY-05568 | BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated
BCMA/TNFRSF17 Protein, Human (His & hFc), PE conjugated
|
Human | HEK293 |
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-recepto... | |||
TMPY-05573 | CD38 Protein, Human, Recombinant (His), PE conjugated
CD38 Protein, Human, Recombinant (His), PE conjugated
|
Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified... |