PROTAC Selection

Cat. No.	Product Name	CAS No.	Purity
T16667	PROTAC Sirt2 Degrader-1 化合物 T16667	2098487-75-1	98%
T16667	PROTAC Sirt2 Degrader-1 is a SirReal-based PROTAC, acts as a Sirt2 degrader, composed of a highly potent and isotype-selective Sirt2 inhibitor, a linker, and a b...
T17249	VZ185 化合物 T17249	2306193-61-1	98%
T17249	VZ185 is an effective and selective dual BRD7/9 PROTAC degrader (DC50s: 4.5 and 1.8 nM, respectively).
T11292	FKBP12 PROTAC dTAG-7 化合物 T11292	2064175-32-0	98%
T11292	FKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional compound that selectively degrades the BET bromodomain transcriptional co-activator BRD4 by connecting BET ...
T5438	PROTAC CDK9 Degrader-1 化合物PROTAC CDK9 Degrader-1	2118356-96-8	98%
T5438	PROTAC CDK9 Degrader-1 是一种选择性 CDK9 降解剂，是由Cereblon 配体和CDK 配体相连的PROTAC。
T13839	PROTAC ER Degrader-4 化合物 T13839	2361114-15-8	98%
T13839	PROTAC ER Degrader-4 is a PROATC degrader of estrogen receptor (ER)(IC50 of 0.8 nM).
T11664	INY-03-041 化合物 T11664	T11664	98%
T11664	INY-03-041, a potent and highly selective PROTAC-based pan-AKT degrader, inhibits AKT1, AKT2, and AKT3 with IC50s of 2.0 nM, 6.8 nM, and 3.5 nM, respectively. Th...
T12556	PROTAC B-Raf degrader 1 化合物 T12556	2364367-27-9	98%
T12556	PROTAC B-Raf degrader 1 is a proteolysis targeting chimera (PROTAC) for the degradation of B-Raf,PROTAC B-Raf degrader 1 With anti-cancer activity.
T13846	PROTAC RIPK degrader-2 化合物 T13846	1801547-16-9	98%
T13846	PROTAC RIPK degrader-2 is a nonpeptidic PROTAC ,and potently targets serine-threonine kinase RIPK2 and has highly selective for RIPK2 degradation.
T13849	PROTAC BET Degrader-1 化合物 T13849	2093386-22-0	98%
T13849	PROTAC BET Degrader-1 is a potent degrader of BET based on PROTAC.
T18631	PROTAC MDM2 Degrader-1 化合物 T18631	2249944-98-5	98%
T18631	PROTAC MDM2 Degrader-1 is a chemical compound that utilizes PROTAC technology to degrade MDM2. This compound is comprised of a highly effective MDM2 inhibitor, a...
T18633	PROTAC MDM2 Degrader-3 化合物 T18633	2249750-23-8	98%
T18633	PROTAC MDM2 Degrader-3 is a compound that leverages PROTAC technology to degrade MDM2. It consists of a highly effective MDM2 inhibitor, a linker, and the MDM2 l...
T18607	PROTAC ER Degrader-3 化合物 T18607	2158322-29-1	98%
T18607	PROTAC ER Degrader-3, an intermediate for the synthesis of PAC, specifically compound LP2. PAC serves as the linker for ADCs and PROTACs that are conjugated to a...
T17910	(S,R,S)-AHPC-PEG2-C4-Cl 化合物 T17910	1835705-57-1	98%
T17910	(S,R,S)-AHPC-PEG2-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-PEG2-C4-Cl is capa...
T17911	(S,R,S)-AHPC-C6-PEG3-C4-Cl 化合物 T17911	1835705-55-9	98%
T17911	(S,R,S)-AHPC-C6-PEG3-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 3-unit PEG linker. (S,R,S)-AHPC-C6-PEG3-C4-Cl i...
T13842	PROTAC IRAK4 degrader-1 化合物 T13842	2360533-90-8	98%
T13842	PROTAC IRAK4 degrader-1 is a degrader of PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4).
T13835	PROTAC BRD4 Degrader-3 化合物 T13835	2313234-00-1	98%
T13835	PROTAC BRD4 Degrader-3 is an efficacious degrader of PROTAC BRD4.
T13785	MZP-54 化合物 T13785	2010159-47-2	98%
T13785	MZP-54 is a selective degrader of BRD3/4 based on PROTAC technology(Kd of 4 nM for Brd4BD2)
T14549	BETd-246 化合物 T14549	2140289-17-2	98%
T14549	BETd-246 is an inhibitor of second-generation and PROTAC-based BET bromodomain (BRD), show antitumor activity.
T12560	PROTAC BRD9 Degrader-1 化合物 T12560	2097971-01-0	98%
T12560	PROTAC BRD9 Degrader-1 is a lead PROTAC BRD9 chemical degrader with IC50 of 13.5 nM.
T16701	QCA570 化合物 T16701	2207569-08-0	98%
T16701	QCA570 is an effective BET degrader based on PROTAC (IC50: 10 nM for BRD4 BD1 Protein).