首页 工具
登录
购物车
SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated

SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated

产品编号 TMPJ-00221   CAS TMPJ-00221
别名: Membrane Protein FOAP-12, Novel Ly9, CRACC, SLAMF7, SLAM Family Member 7, CD2-Like Receptor-Activating Cytotoxic Cells, CD2 Subset 1, CD319, CS1, Protein 19A

SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-cell lines, or T-cell lines. Although the cytoplasmic domain of CS1 contains immunoreceptor tyrosine-based switch motifs (ITSM), which enables to recruite signaling lymphocyte activation molecule (SLAM)-associated protein (SAP/SH2D1A), it activates NK cells in the absence of a functional SAP. SLAMF7 positively regulated natural killer cell functions by a mechanism dependent on the adaptor EAT-2 but not the related adaptor SAP. However, in the absence of EAT-2, CRACC potently inhibited natural killer cell function. It was also inhibitory in T cells, which are typically devoid of EAT-2. Thus, SLAMF7 can exert activating or inhibitory influences on cells of the immune system depending on cellular context and the availability of effector proteins.

TargetMol的所有产品和服务仅用于科学研究,不能被用于人体,我们也不向个人提供产品和服务。
SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated Chemical Structure
SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated, CAS TMPJ-00221
规格 价格/CNY 货期 数量
20 μg ¥ 2,260 5日内发货
100 μg ¥ 6,130 5日内发货

SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated 的其他形式现货产品:

Coppersensor 1 SLAMF7 Protein, Human, Recombinant (His)
产品目录号及名称: SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated (TMPJ-00221)
点击图片重新获取验证码
TargetMol batch loading
更多批次查询请联系客服
生物活性
化学信息
存储 & 溶解度
产品描述 SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-cell lines, or T-cell lines. Although the cytoplasmic domain of CS1 contains immunoreceptor tyrosine-based switch motifs (ITSM), which enables to recruite signaling lymphocyte activation molecule (SLAM)-associated protein (SAP/SH2D1A), it activates NK cells in the absence of a functional SAP. SLAMF7 positively regulated natural killer cell functions by a mechanism dependent on the adaptor EAT-2 but not the related adaptor SAP. However, in the absence of EAT-2, CRACC potently inhibited natural killer cell function. It was also inhibitory in T cells, which are typically devoid of EAT-2. Thus, SLAMF7 can exert activating or inhibitory influences on cells of the immune system depending on cellular context and the availability of effector proteins.
别名 Membrane Protein FOAP-12, Novel Ly9, CRACC, SLAMF7, SLAM Family Member 7, CD2-Like Receptor-Activating Cytotoxic Cells, CD2 Subset 1, CD319, CS1, Protein 19A
分子量 35-55 KDa, reducing conditions
CAS No. TMPJ-00221

存储

Lyophilized powder: -20~-80°C for 1 year

TargetMol Calculator计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器
=
X
X
X
=
X
=
/
g/mol

输入分子式,点击计算,可计算出产品的分子量。

TargetMol Calculator剂量换算

对于不同动物的给药剂量换算,您也可以参考 更多...

TargetMol Calculator 体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。

母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。

体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。

第一步:请输入动物实验的基本信息
剂量
mg/kg
每只动物体重
g
给药体积
μL
动物数量
第二步:请输入动物体内配方组成,不同的产品配方组成不同,如有配方需求,可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% ddH2O
计算 重置

技术支持

您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。

Keywords

SLAMF7 Protein, Human, Recombinant (His & Avi), Biotinylated TMPJ-00221 Membrane Protein FOAP-12 Novel Ly9 CD 319 CRACC CD-319 SLAMF7 SLAM Family Member 7 CS 1 CD2-Like Receptor-Activating Cytotoxic Cells CD2 Subset 1 CD319 CS1 SLAMF 7 Protein 19A CS-1 SLAMF-7 Inhibitor inhibitor inhibit

 

TargetMol Loading
陶术
生物
TargetMol®中国区唯一合作伙伴
点击进入陶术生物官网陶术生物
联系我们
400-820-0310

上海市静安区江场三路238号8楼