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Placental Lactogen/CSH1 Protein, Human, Recombinant (His), Biotinylated

Placental Lactogen/CSH1 Protein, Human, Recombinant (His), Biotinylated

产品编号 TMPY-05546
别名: hCS-A, CS-1, CSA, hCS-1, PL, CSMT, chorionic somatomammotropin hormone 1 (placental lactogen)

Chorionic somatomammotropin hormone, also known as Choriomammotropin, Lactogen, Placental lactogen and CSH1, is a secreted protein which belongs to thesomatotropin / prolactin family. CSH1 is produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. The CSH1 gene is member of the GH gene cluster on 17q, which consists of two growth hormone genes and three CSH genes. Genomic alterations in the GH cluster are well known, causing different phenotypes depending on the size of the deletion and the genes involved. The increased prevalence of hemizygosity of CSH1 in population in comparison to controls indicates a role for CSH1 haploinsufficiency in the etiology of growth retardation. Investigation of CSH1 deletions in further SRS and growth retarded patients will enable us to establish under which circumstances haploinsufficiency of CSH1 is likely to result in clinical changes.

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Placental Lactogen/CSH1 Protein, Human, Recombinant (His), Biotinylated Chemical Structure
Placental Lactogen/CSH1 Protein, Human, Recombinant (His), Biotinylated, CAS N/A
规格 价格/CNY 货期 数量
20 μg ¥ 2,440 5日内发货
100 μg ¥ 5,810 5日内发货

Placental Lactogen/CSH1 Protein, Human, Recombinant (His), Biotinylated 的其他形式现货产品:

Coppersensor 1 SLAMF7 Protein, Human, Recombinant (His)
产品目录号及名称: Placental Lactogen/CSH1 Protein, Human, Recombinant (His), Biotinylated (TMPY-05546)
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存储 & 溶解度
参考文献
产品描述 Chorionic somatomammotropin hormone, also known as Choriomammotropin, Lactogen, Placental lactogen and CSH1, is a secreted protein which belongs to thesomatotropin / prolactin family. CSH1 is produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. The CSH1 gene is member of the GH gene cluster on 17q, which consists of two growth hormone genes and three CSH genes. Genomic alterations in the GH cluster are well known, causing different phenotypes depending on the size of the deletion and the genes involved. The increased prevalence of hemizygosity of CSH1 in population in comparison to controls indicates a role for CSH1 haploinsufficiency in the etiology of growth retardation. Investigation of CSH1 deletions in further SRS and growth retarded patients will enable us to establish under which circumstances haploinsufficiency of CSH1 is likely to result in clinical changes.
别名 hCS-A, CS-1, CSA, hCS-1, PL, CSMT, chorionic somatomammotropin hormone 1 (placental lactogen)
分子量 23.7 kDa (predicted)

存储

Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month

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TargetMol Library Books参考文献

1. Prager,S. et al., 2003,Genet Test. 7 (3):259-63. 2. Singleton, DR. et al., 2004, Microbiology. 150 (Pt 2): 285-92. 3. Chen,Y. et al., 2008, Cancer Res. 68 (23):9729-34.

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Keywords

Placental Lactogen/CSH1 Protein, Human, Recombinant (His), Biotinylated hCS-A CS 1 CS-1 CSA hCS-1 placental lactogen CS1 PL CSMT chorionic somatomammotropin hormone 1 chorionic somatomammotropin hormone 1 (placental lactogen) Inhibitor inhibitor inhibit

 

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