Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T12893 | SGLT inhibitor-1
化合物 T12893
|
2247314-23-2 | 98% |
|
SGLT inhibitor-1 is a potentsodium glucose co-transporter proteins (SGLTs) dual inhibitor(hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively). | ||||
T12892 | SGL5213
化合物 T12892
|
1240305-17-2 | 98% |
|
SGL5213 is an oral active and low-absorbable inhibitor of sodium-dependent glucose cotransporter 1 (SGLT1)(hSGLT1 and hSGLT2 with IC50 values of 29 nM and 20 nM ... | ||||
T15752 | Licogliflozin
化合物Licogliflozin
|
1291094-73-9 | 98% |
|
Licogliflozin (LIK066) 是钠-葡萄糖协同转运蛋白 (SGLT1和SGLT2) 的有效抑制剂。 | ||||
TN4784 | Picraline
化合物 TN4784
|
2671-32-1 | 98% |
|
A series of a hydroxy substituted derivatives 21-28 at C-17 of the Picraline-type alkaloids have been derived as having potent SGLT inhibitory activity. | ||||
T15807 | LY2794193
化合物 T15807
|
2173037-97-1 | 98% |
|
LY2794193 is a highly effective and selective agonist of the mGlu3 receptor (hmGlu3 Ki=0.927 nM,EC50=0.47 nM; hmGlu2 Ki=412 nM,EC50=47.5 nM). | ||||
T11671 | IRAK inhibitor 4 trans
化合物 T11671
|
T11671 | 98% |
|
IRAK inhibitor 4 is a compound that functions as an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK4). It specifically targets and inhibits the act... | ||||
T15505 | HSK0935
化合物 T15505
|
1638851-44-1 | 98% |
|
HSK0935 is a highly selective and orally available SGLT2 inhibitor (IC50: 1.3 nM). It has antihyperglycemic activities. | ||||
TN4399 | Kushenol C
化合物 TN4399
|
99119-73-0 | 98% |
|
Kushenol C is a good 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenger, and it exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2).... | ||||
T17221 | Velagliflozin
化合物 T17221
|
946525-65-1 | 98% |
|
Velagliflozin is an orally available inhibitor of sodium-glucose cotransporter 2. | ||||
T2385 | Ipragliflozin
伊格列净
|
761423-87-4 | 99.97% |
|
Ipragliflozin (ASP1941) 是一种口服有效的,选择性的 SGLT2抑制剂,对人 SGLT2 和 SGLT1,大鼠 SGLT2 和 SGLT1,小鼠 SGLT2 和 SGLT1 的 IC50分别为 7.38 和 1876 nM,6.73 和 1166 nM,5.64 和 1380 nM。Ipraglif... | ||||
T1782L | Canagliflozin hemihydrate
卡格列净半水合物
|
928672-86-0 | 99.96% |
|
Canagliflozin hemihydrate (TA 7284) (JNJ28431754 hemihydrate) 是一种选择性的 SGLT2 抑制剂,作用于表达 mSGLT2,rSGLT2 和 hSGLT2 的 CHO 细胞,IC50 分别为 2 nM,3.7 nM 和 4.4 nM。 | ||||
T1766 | Empagliflozin
恩格列净
|
864070-44-0 | 99.89% |
|
Empagliflozin (BI 10773) 是一种 SGLT-2 抑制剂 (IC50=3.1 nM),具有有效的和选择性,对 SGLT-1/4/5/6 的选择性高 300 倍以上。Empagliflozin 可用于治疗二型糖尿病。 | ||||
TN1856 | Leachianone A
里查酮 A
|
97938-31-3 | 99.79% |
|
Leachianone A (Isokurarinone) 是从槐花中分离的一种天然产物,可诱导细胞凋亡,具有抗疟疾、抗炎和细胞毒性作用。 | ||||
T1782 | Canagliflozin
卡格列净
|
842133-18-0 | 99.76% |
|
Canagliflozin (JNJ 28431754AAA) 是SGLT2的选择性抑制剂,在表达 mSGLT2,rSGLT2 和 hSGLT2 的 CHO 细胞上,IC50分别为 2 nM,3.7 nM 和 4.4 nM。 | ||||
T2924 | Phloretin
根皮素
|
60-82-2 | 99.76% |
|
Phloretin (NSC-407292) 是从苹果树叶中提取的一种查耳酮,具有抗炎、抗氧化和抗癌活性。它是真核尿素转运蛋白抑制剂,可阻断 VacA 介导的尿素和离子转运,有潜力用于类风湿性关节炎和过敏性气道炎症的相关研究。 | ||||
T2389 | Dapagliflozin
达格列净
|
461432-26-8 | 99.74% |
|
Dapagliflozin (BMS-512148) 竞争性的葡萄糖协同转运蛋白2 (SGLT2) 抑制剂,可促进尿液中葡萄糖的排泄,在糖尿病 (DM) 研究中具有价值。Dapagliflozin 诱导 HIF1表达并减轻肾脏 IR 损伤。 | ||||
T2922 | Phlorizin
根皮苷
|
60-81-1 | 99.68% |
|
Phlorizin (Phloridzin) 是非选择性的SGLT 抑制剂,也是Na+/K+-ATPase 抑制剂,对于hSGLT1和hSGLT2的Ki 值分别为 300 和 39 nM。 | ||||
T9590 | T-1095
化合物T-1095
|
209746-59-8 | 99.56% |
|
T-1095 是一种口服有活性的Na+-葡萄糖协同转运蛋白选择性抑制剂,能够抑制 SGLT1 (IC50:22.8 µm) 及 SGLT2 (IC50:2.3 µm) 。它可用于研究糖尿病。 | ||||
T4460 | Dapagliflozin ((2S)-1,2-propanediol, hydrate)
达格列净 (2S)-1,2-丙二醇水合物
|
960404-48-2 | 99.39% |
|
Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) 是 Dapagliflozin 1,2-propanediol, hydrate 的 S 型异构体,是竞争性葡萄糖协同转运蛋白2 抑制剂,可促进... | ||||
T3547 | Sotagliflozin
化合物Sotagliflozin
|
1018899-04-1 | 99.37% |
|
Sotagliflozin (LP-802034) 是有效的SGLT1/2抑制剂,用作抗糖尿病剂。 |