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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T3213 |
Hematoporphyrin dihydrochloride
血卟啉二盐酸盐,Hematoporphyrin IX dihydrochloride |
Apoptosis; Others; Endogenous Metabolite | Apoptosis; Metabolism; Others |
Hematoporphyrin dihydrochloride (Hematoporphyrin IX dihydrochloride) 是一种光敏剂,是血红素结合蛋白亲和色谱底物。它暴露在红光下时,可诱导 U87 胶质瘤细胞凋亡,并降低体内肿瘤的生长。 | |||
T76995 |
Sotatercept
|
||
Sotatercept (ACE-011) 是一种可溶性激活素受体 2A (ACVR2A) 型 IgGFc 融合蛋白。Sotatercept 结合了激活素和生长分化因子,试图恢复生长促进和生长抑制信号通路之间的平衡。Sotatercept 在肺动脉高压、贫血、骨质流失、红细胞生成、多发性骨髓瘤 (MM) 溶骨性病变中有潜在的应用。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN7052 |
Crocin III
西红花苷 III,Crocetin-mono-(β-D-gentiobiosyl)-ester |
Others | Others |
Crocin III (Crocetin-mono-(β-D-gentiobiosyl)-ester) 是一种来自于藏红花 (Crocus sutivusL)的藏红花素。Crocins 可用作香料和着色剂。Crocins 具有抗炎作用,能够抑制肿瘤细胞的细胞生长。 | |||
T10886 |
Crocetine dimethyl ester
Dimethylcrocetin |
Antioxidant | oxidation-reduction |
Crocetine dimethyl ester (Dimethylcrocetin) 是一种藏红花素衍生物,具有抗氧化活性,抑制 AChE 活性,抑制细胞生长分化。 | |||
T1331 |
Riboflavin phosphate sodium
Riboflavin 5'-phosphate sodium,核黄素磷酸钠(维生素B2),Vitamin B2 Phosphate Sodium Salt,Flavin mononucleotide,FMN,核黄素磷酸钠,FMN-Na,riboflavin-5'-phosphate |
Endogenous Metabolite | Metabolism |
Riboflavin phosphate sodium (FMN) 是 riboflavin 的磷酸钠盐形式,riboflavin 是一种水溶性和必需的微量营养素,是自然产生的维生素B复合物的主要生长促进因子。Riboflavin phosphate sodium 转化为2种辅酶,黄素单核苷酸(FMN)和黄素腺嘌呤二核苷酸(FAD),这两种辅酶通过帮助脂肪、碳水化合物和蛋白质的代谢来产生能量,并且是红细胞形成和呼吸、抗体产生以及调节人体生长和繁殖所必需的。 | |||
TN2496 |
1,4-Anthraquinone
|
Others | Others |
1,4-Anthraquinone 是一种抗癌药物,在体外与柔红霉素相同纳摩尔范围内阻断核苷转运、抑制大分子合成、诱导 DNA 片段化并降低 L1210 白血病细胞的生长和活力。它被提议为一种用于高效液相色谱 (HPLC) 测定药物制剂中 N-乙酰半胱氨酸 (NAC) 和卡托普利 (CAP) 的新型柱前试剂。 | |||
TN1567 |
Delphinidin chloride
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Estrogen Receptor/ERR; VEGFR | Angiogenesis; Endocrinology/Hormones; Tyrosine Kinase/Adaptors |
Delphinidin chloride 是一种花青素,是一种可从浆果和红酒中分离得到的天然植物色素,是某些花青素的前体。Delphinidin chloride 诱导血管内皮释放一氧化氮,引起血管松弛。在1 ~ 40 μM 剂量下,对上皮生长因子受体的信号传导和雌激素受体α的表达有抑制作用,与细胞凋亡和自噬有关。Delphinidin chloride 能调节 JAK/STAT3 和 MAPKinase 信号传导。Delphinidin 还能抑制 p300/CBP 的组蛋白乙酰转移酶活性(IC50 在约为30 μM) |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00443 |
EPO/Erythropoietin Protein, Mouse, Recombinant
红细胞生长素,erythropoietin |
Mouse | HEK293 Cells |
EPO/Erythropoietin Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.6 kDa and the accession number is P07321. | |||
TMPJ-00071 |
EPO/Erythropoietin Protein, Human, Recombinant (His)
Erythropoietin,EPO,红细胞生长素,Epoetin |
Human | HEK293 Cells |
Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoietin is a member of the EPO/TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. The differentiation of CFU-E (Colony Forming Unit-Erythroid) cells into erythrocytes can only be accomplished in the presence of EPO. Physiological levels of EP... | |||
TMPY-00639 |
EPO/Erythropoietin Protein, Human, Recombinant (hFc)
红细胞生长素,MVCD2,Erythropoietin,EP |
Human | HEK293 Cells |
EPO/Erythropoietin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.1 kDa and the accession number is G9JKG7. | |||
TMPY-02073 |
EPO/Erythropoietin Protein, Rat, Recombinant (His)
红细胞生长素,erythropoietin |
Rat | Baculovirus Insect Cells |
EPO/Erythropoietin Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 20 kDa and the accession number is P29676-1. | |||
TMPY-02986 |
EPO/Erythropoietin Protein, Mouse, Recombinant (His)
红细胞生长素,erythropoietin |
Mouse | HEK293 Cells |
EPO/Erythropoietin Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20 kDa and the accession number is P07321. | |||
TMPY-00462 |
EPO/Erythropoietin Protein, Cynomolgus, Recombinant (His)
红细胞生长素,erythropoietin |
Cynomolgus | HEK293 Cells |
EPO/Erythropoietin Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.7 kDa and the accession number is XP_005549312.1. | |||
TMPK-00077 |
EPO/Erythropoietin Protein, Human, Recombinant
EPO,MVCD2,红细胞生长素,Epoetin,Erythropoietin,EP |
Human | HEK293 Cells |
Erythropoietin (EPO) is a circulating hormone conventionally considered to be responsible for erythropoiesis. In addition to facilitating red blood cell production, EPO has pluripotent potential, such as for cognition improvement, neurogenesis, and anti-fibrotic, anti-apoptotic, anti-oxidative, and anti-inflammatory effects. |